An Oxidation‐Enhanced Magnetic Resonance Imaging Probe for Visual and Specific Detection of Singlet Oxygen Generated in Photodynamic Cancer Therapy In Vivo

2020 ◽  
Vol 9 (16) ◽  
pp. 2000533
Author(s):  
Kai Deng ◽  
Bo Wu ◽  
Cai‐Xia Wang ◽  
Qian Wang ◽  
Hui Yu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Resonance Imaging ◽  
Specific Detection ◽  
Imaging Probe ◽  
Photodynamic Cancer Therapy

Multifunctional nanoplatform for enhanced photodynamic cancer therapy and magnetic resonance imaging

2017 ◽  
Vol 151 ◽  
pp. 384-393 ◽  
Author(s):  
Yongwei Hao ◽  
Bingxiang Zhang ◽  
Cuixia Zheng ◽  
Mengya Niu ◽  
Haochen Guo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cancer Therapy ◽  
Resonance Imaging ◽  
Photodynamic Cancer Therapy

Design of Chemical Shift-Switching19F Magnetic Resonance Imaging Probe for Specific Detection of Human Monoamine Oxidase A

2011 ◽  
Vol 133 (36) ◽  
pp. 14208-14211 ◽  
Author(s):  
Koya Yamaguchi ◽  
Ryosuke Ueki ◽  
Hiroshi Nonaka ◽  
Fuminori Sugihara ◽  
Tetsuya Matsuda ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Chemical Shift ◽  
Monoamine Oxidase ◽  
Monoamine Oxidase A ◽  
Resonance Imaging ◽  
Specific Detection ◽  
Imaging Probe

Monitoring stem cell migration in the nervous system by in vivo magnetic resonance imaging

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S692-S692
Author(s):  
Mathias Hoehn ◽  
Uwe Himmelreich ◽  
Ralph Weber ◽  
Pedro Ramos-Cabrer ◽  
Susanne Wegener ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Nervous System ◽  
Stem Cell ◽  
Cell Migration ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Stem Cell Migration

Supramolecular Enhancement of Aminoxyl ORCA Contrast Agents

2019 ◽  
Author(s):  
Hamilton Lee ◽  
Jenica Lumata ◽  
Michael A. Luzuriaga ◽  
Candace Benjamin ◽  
Olivia Brohlin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Side Effects ◽  
Magnetic Resonance ◽  
Tobacco Mosaic Virus ◽  
Contrast Agents ◽  
Single Molecule ◽  
Organic Radical ◽  
Resonance Imaging ◽  
Physiological Conditions

<div><div><div><p>Many contrast agents for magnetic resonance imaging are based on gadolinium, however side effects limit their use in some patients. Organic radical contrast agents (ORCAs) are potential alternatives, but are reduced rapidly in physiological conditions and have low relaxivities as single molecule contrast agents. Herein, we use a supramolecular strategy where cucurbit[8]uril binds with nanomolar affinities to ORCAs and protects them against biological reductants to create a stable radical in vivo. We further over came the weak contrast by conjugating this complex on the surface of a self-assembled biomacromolecule derived from the tobacco mosaic virus.</p></div></div></div>

Sign in / Sign up

Export Citation Format

Share Document