A Hierarchical‐Structured Mineralized Nanofiber Scaffold with Osteoimmunomodulatory and Osteoinductive Functions for Enhanced Alveolar Bone Regeneration

2021 ◽  
pp. 2102236
Author(s):  
Yang He ◽  
Mi Tian ◽  
Xilin Li ◽  
Jianwen Hou ◽  
Song Chen ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Alveolar Bone ◽  
Nanofiber Scaffold

Optimization and fabrication of alginate scaffold for alveolar bone regeneration with sufficient drug release

2021 ◽  
Author(s):  
Maryam Soleimani ◽  
Ariyan Asgharzadeh Salmasi ◽  
Samaneh Asghari ◽  
Hamed Joneidi Yekta ◽  
Bahareh Kamyab Moghadas ◽  
...  
Keyword(s):  
Drug Release ◽  
Bone Regeneration ◽  
Alveolar Bone ◽  
Alginate Scaffold

scholarly journals Leucocyte- and Platelet-Rich Fibrin Block: Its Use for the Treatment of a Large Cyst with Implant-Based Rehabilitation

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 180 ◽  
Author(s):  
Rodolfo Mauceri ◽  
Denise Murgia ◽  
Orazio Cicero ◽  
Luigi Paternò ◽  
Luca Fiorillo ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bone Defect ◽  
Bone Healing ◽  
Bone Substitute ◽  
Alveolar Bone ◽  
Critical Size ◽  
Large Bone ◽  
Alveolar Bone Defect ◽  
Positive Results ◽  
Autologous Platelet

The management of critical-size bone defects is still demanding. Recently, autologous platelet concentrates in combination with bone substitute have been applied and reported in a few studies. Our aim is to report the healing of a critical-size alveolar bone defect treated with a new bone regeneration technique by means of L-PRF and L-PRF blocks. A 45-year-old woman presented a large cystic lesion; the extraction of three teeth, a cyst removal procedure, and bone regeneration procedures with L-PRF and L-PRF blocks were planned. The L-PRF block was prepared by mixing a bone substitute with a piece of L-PRF membrane and liquid fibrinogen. Additionally, after bone healing an implant-based rehabilitation was optimally performed. On the basis of the positive results, in terms of bone healing and tissue regeneration in a large bone defect, the application of L-PRF and L-PRF blocks, in agreement with the scarce literature, is suggested as a feasible procedure in selected cases.

scholarly journals Delivery Systems and Role of Growth Factors for Alveolar Bone Regeneration in Dentistry

10.5772/55580 ◽  
2013 ◽  
Author(s):  
Stefano Sivolella ◽  
Marleen De ◽  
Giulia Brunello ◽  
Sara Ricci ◽  
Drazen Tadic ◽  
...  
Keyword(s):  
Growth Factors ◽  
Bone Regeneration ◽  
Alveolar Bone ◽  
Delivery Systems

Selective piezocision-assisted orthodontic treatment combined with minimally invasive alveolar bone regeneration: A proof-of-concept

2018 ◽  
Vol 16 (4) ◽  
pp. 652-664 ◽  
Author(s):  
Carole Charavet ◽  
Geoffrey Lecloux ◽  
Annick Bruwier ◽  
Bart Vandenberghe ◽  
Michel Le Gall ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Bone Regeneration ◽  
Orthodontic Treatment ◽  
Alveolar Bone ◽  
Proof Of Concept

scholarly journals PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review

2019 ◽  
Vol 13 (3) ◽  
pp. 258-265
Author(s):  
Marcelo Parra ◽  
María Paz Moya ◽  
Carolina Rebolledo ◽  
Ziyad S Haidar ◽  
Juan Pablo Alister ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Regeneration ◽  
Alveolar Bone

scholarly journals Composite Sponges for in Situ Alveolar Bone Regeneration Following Tooth Extraction

2017 ◽  
Vol 131 (3) ◽  
pp. 580-584 ◽  
Author(s):  
Z.A. Guclu ◽  
A.P. Hurt ◽  
L. Ohia ◽  
N.J. Coleman
Keyword(s):  
Bone Regeneration ◽  
Tooth Extraction ◽  
Alveolar Bone

Micro-Computed Tomography Analysis on Administration of Mesenchymal Stem Cells - Bovine Teeth Scaffold Composites for Alveolar Bone Tissue Engineering

2021 ◽  
Vol 52 ◽  
pp. 86-96
Author(s):  
Desi Sandra Sari ◽  
Fourier Dzar Eljabbar Latief ◽  
Ferdiansyah ◽  
Ketut Sudiana ◽  
Fedik Abdul Rantam
Keyword(s):  
Computed Tomography ◽  
Tissue Engineering ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Regeneration ◽  
Bone Growth ◽  
Alveolar Bone ◽  
Micro Computed Tomography ◽  
Freeze Dried ◽  
Significant Difference

The tissue engineering approach for periodontal tissue regeneration using a combination of stem cells and scaffold has been vastly developed. Mesenchymal Stem Cells (MSCs) seeded with Bovine Teeth Scaffold (BTSc) can repair alveolar bone damage in periodontitis cases. The alveolar bone regeneration process was analyzed by micro-computed tomography (µ-CT) to observe the structure of bone growth and to visualize the scaffold in 3-Dimensional (3D). The purpose of this study is to analyze alveolar bone regeneration by µ-CT following the combination of MSCs and bovine teeth scaffold (MSCs-BTSc) implantation in the Wistar rat periodontitis model. Methods. MSCs were cultured from adipose-derived mesenchymal stem cells of rats. BTSc was taken from bovine teeth and freeze-dried with a particle size of 150-355 µm. MSCs were seeded on BTSc for 24 hours and transplanted in a rat model of periodontitis. Thirty-five Wistar rats were made as periodontitis models with LPS induction from P. gingivalis injected to the buccal section of interproximal gingiva between the first and the second mandibular right-molar teeth for six weeks. There were seven groups (control group, BTSc group on day 7, BTSc group on day 14, BTSc group on day 28, MSCs-BTSc group on day 7, MSCs-BTSc group on day 14, MSCs-BTSc group on day 28). The mandibular alveolar bone was analyzed and visualized in 3D with µ-CT to observe any new bone growth. Statistical Analysis. Group data were subjected to the Kruskal Wallis test followed by the Mann-Whitney (p <0.05). The µ-CT qualitative analysis shows a fibrous structure, which indicates the existence of new bone regeneration. Quantitative analysis of the periodontitis model showed a significant difference between the control model and the model with the alveolar bone resorption (p <0.05). The bone volume and density measurements revealed that the MSCs-BTSc group on day 28 formed new bone compared to other groups (p <0.05). Administration of MSCs-BTSc combination has the potential to form new alveolar bone.

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