Ampoule‐Like Microvolume Containers with Transparent Code for Easy‐to‐Use and Space‐Saving Storage of Small‐Volume Biospecimens

2021 ◽  
pp. 2101266
Author(s):  
Hyeli Kim ◽  
Yeongjae Choi ◽  
Amos C. Lee ◽  
Junghyun Bae ◽  
Jinsik Yoon ◽  
...  
Keyword(s):  
Author(s):  
Jyrki Kimmel

AbstractModern optical multi-camera systems require integrating many camera modules in a small volume. A new space-saving concept for such imaging systems is presented, based on intersecting optical paths that utilize one or more common elements for the respective optical paths. The principles for the optimization for such systems is examined, providing the theory for geometric optimization constraints. These principles can become useful in designing e. g. spatially challenging 360-degree imaging systems for surveillance and consumer applications.


Author(s):  
D.P. Bazett-Jones ◽  
F.P. Ottensmeyer

Dark field electron microscopy has been used for the study of the structure of individual macromolecules with a resolution to at least the 5Å level. The use of this technique has been extended to the investigation of structure of interacting molecules, particularly the interaction between DNA and fish protamine, a class of basic nuclear proteins of molecular weight 4,000 daltons.Protamine, which is synthesized during spermatogenesis, binds to chromatin, displaces the somatic histones and wraps up the DNA to fit into the small volume of the sperm head. It has been proposed that protamine, existing as an extended polypeptide, winds around the minor groove of the DNA double helix, with protamine's positively-charged arginines lining up with the negatively-charged phosphates of DNA. However, viewing protamine as an extended protein is inconsistent with the results obtained in our laboratory.


Author(s):  
E. Zeitler ◽  
M. G. R. Thomson

In the formation of an image each small volume element of the object is correlated to an areal element in the image. The structure or detail of the object is represented by changes in intensity from element to element, and this variation of intensity (contrast) is determined by the interaction of the electrons with the specimen, and by the optical processing of the information-carrying electrons. Both conventional and scanning transmission electron microscopes form images which may be considered in this way, but the mechanism of image construction is very different in the two cases. Although the electron-object interaction is the same, the optical treatment differs.


Author(s):  
Ng Sea Chooi ◽  
Chor Theam Hock ◽  
Ma Choo Thye ◽  
Khoo Poh Tshin ◽  
Dan Bockelman

Abstract Trends in the packaging of semiconductors are towards miniaturization and high functionality. The package-on-package(PoP) with increasing demands is beneficial in cost and space saving. The main failure mechanisms associated with PoP technology, including open joints and warpage, have created a lot of challenges for Assembly and Failure Analysis (FA). This paper outlines the sample preparation process steps to overcome the challenges to enable successful failure analysis and optical probing.


2020 ◽  
Vol 81 (4) ◽  
pp. 198-203
Author(s):  
Lisa M. Duizer ◽  
Heather H. Keller

Prevalence of micronutrient malnutrition is high in individuals living in long-term care (LTC) homes with many individuals consuming low levels of vitamins B6, D, and E; folate; calcium; magnesium; and zinc. The focus of this research was to identify strategies and challenges encountered during development of micronutrient-dense menus for use in Ontario LTC homes and to examine costs associated with development of a menu with acceptable micronutrients. Semi-structured open-ended interviews were conducted with 13 menu planners (7 dietitians, 6 nutrition managers) in diverse LTC homes in Ontario. Data were thematically analyzed. A 7-day hypothetical menu meeting all nutrient requirements was developed and costed. Analysis of the interview data showed that menus are planned according to the Canada’s Food Guide (2007) and focus placed on Dietary Reference Intakes of protein, fibre, calcium, and sodium. Little focus is placed on micronutrients. Flexibility in foods offered was important to accommodate the small volume of food consumed. Resident preferences were balanced against nutritional requirements. Challenges included planning for diverse populations, managing portion sizes, and balancing the budget. A hypothetical menu planned to contain adequate levels of all micronutrients is 49% higher in food costs than the amount currently provided to Ontario LTC homes.


Author(s):  
М. В. Дзисюк

Definitions of concept and sphere of the concept are widely used in different aspects of modern linguistics. There is no single understanding of these notions and universal methodology of research has not been invented by linguists yet. This predetermines topicality of the article. The aim of our research is analysis, generalization, and systematization of different approaches to the interpretation of the notion ‘concept’ that exist in modern linguistics. It results in the following tasks: analysis of existing definitions of concept and its division into certain ranges and defining classification features. Modern linguists raise the questions of the conceptual and linguistic image of the world, the role of a human factor in its formation and interaction as in a linguistic process more frequently and it is defined as a fact in today’s linguistic scientific literature. The problem of individual language formation, poetic one in particular gains important meaning in this context. Ukrainian linguists use the notion of ‘concept’ for a long time now although they adhere to different views on its definition. Researches of the question define two major approaches in the analysis of the notion ‘concept’ that is linguistic-cognitive and linguistic-cultural. We can claim that words-concepts are agents between material reality and the ideal world that is synthesized in poetry, carriers of sense since with their help the versatility of the real world correlates with eternal spiritual values. Therefore, main features of the notion ‘concept’ in which objectively-cognitive and subjectively-creative features are combines are as follow sensual authenticity, time-spatial features, mediation between material and spiritual, semantic filling, ability to polysemy. A word with a generally symbolic meaning that is implemented in a language process through literary techniques typical for poet’s idiotype is the main core of the concept. The concept in poetic language formation by modern Uman poets is semantically integral, fulfilled, able to penetrate into other concepts and absorb semantically narrower images saving unity and semantic independence, varying numerous interpretations that project it in a certain semantic space, saving potential of real reflection.


2020 ◽  
Author(s):  
Chaoming Fang ◽  
Yixuan Wang ◽  
Shuo Gao

In order to quantify the manipulation process of acupuncture, in this article, a piezoelectric glove based wearable stress sensing system is presented. Served as the sensitive element with small volume and high tensile resistance, PVDF greatly meet the need of quantitative analysis. Through piezoelectric force sensing glove, the system is capable of detecting both perpendicular stress as well as shear stress. Besides, key parameters including peak stress at needle are detected and extracted, potentially allowing for a higher learning efficiency hence advancing the development of acupuncture.


1983 ◽  
Vol 18 (1) ◽  
pp. 129-150 ◽  
Author(s):  
Mark K. Watson ◽  
R.R. Hudgins ◽  
P.L. Silveston

Abstract Internal wave motion was studied in a laboratory rectangular, primary clarifier. A photo-extinction device was used as a turbidimeter to measure concentration fluctuations in a small volume within the clarifier as a function of time. The signal from this device was fed to a HP21MX minicomputer and the power spectrum plotted from data records lasting approximately 30 min. Results show large changes of wave amplitude as frequency increases. Two distinct regions occur: one with high amplitudes at frequencies below 0.03 Hz, the second with very small amplitudes appears for frequencies greater than 0.1 Hz. The former is associated with internal waves, the latter with flow-generated turbulence. Depth, velocity in the clarifier and inlet suspended solids influence wave amplitudes and the spectra. A variation with position or orientation of the probe was not detected. Contradictory results were found for the influence of flow contraction baffles on internal wave amplitude.


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