scholarly journals Genetic causes of intellectual disability in a birth cohort: A population‐based study

2015 ◽  
Vol 167 (6) ◽  
pp. 1204-1214 ◽  
Author(s):  
Simone M. Karam ◽  
Mariluce Riegel ◽  
Sandra L. Segal ◽  
Têmis M. Félix ◽  
Aluísio J. D. Barros ◽  
...  
Keyword(s):  
Intellectual Disability ◽  
Birth Cohort ◽  
Population Based ◽  
Population Based Study ◽  
Genetic Causes

scholarly journals Maternal vitamin D deficiency and the risk of autism spectrum disorders: population-based study

BJPsych Open ◽  
2016 ◽  
Vol 2 (2) ◽  
pp. 170-172 ◽  
Author(s):  
Cecilia Magnusson ◽  
Kyriaki Kosidou ◽  
Christina Dalman ◽  
Michael Lundberg ◽  
Brian K. Lee ◽  
...  
Keyword(s):  
Vitamin D ◽  
Intellectual Disability ◽  
Vitamin D Deficiency ◽  
Population Based ◽  
Autism Spectrum ◽  
Population Based Study ◽  
Maternal Vitamin ◽  
Increase Risk ◽  
Spectrum Disorders ◽  
The Relationship

BackgroundMaternal vitamin D deficiency may increase risk of autism spectrum disorder (ASD), but direct evidence is lacking.AimsTo clarify the relationship between maternal vitamin D deficiency and offspring risk of ASD with and without intellectual disability.MethodUsing a register-based total population study (N=509 639), we calculated adjusted odds ratios (aORs) and 95% confidence intervals (CIS) of ASD with and without intellectual disability in relation to lifetime diagnoses of maternal vitamin D deficiency. Although rare, such deficiency was associated with offspring risk of ASD with, but not without, intellectual disability (aORs 2.51, 95% CI 1.22–5.16 and 1.28, 0.68–2.42). Relationships were stronger in non-immigrant children.ConclusionsIf reflecting associations for prenatal hypovitaminosis, these findings imply gestational vitamin D substitution as a means of ASD prevention.

scholarly journals Birth Cohort Effects on Incidence of Lung Cancers: A Population-based Study in Nagasaki, Japan

2000 ◽  
Vol 91 (10) ◽  
pp. 960-965 ◽  
Author(s):  
Hiroshi Soda ◽  
Mikio Oka ◽  
Midori Soda ◽  
Katsumi Nakatomi ◽  
Shigeru Kawabata ◽  
...  
Keyword(s):  
Birth Cohort ◽  
Population Based ◽  
Cohort Effects ◽  
Population Based Study ◽  
Lung Cancers

Array-CGH in children with mild intellectual disability: a population-based study

2014 ◽  
Vol 174 (1) ◽  
pp. 75-83 ◽  
Author(s):  
Charles Coutton ◽  
Klaus Dieterich ◽  
Véronique Satre ◽  
Gaëlle Vieville ◽  
Florence Amblard ◽  
...  
Keyword(s):  
Intellectual Disability ◽  
Array Cgh ◽  
Population Based ◽  
Mild Intellectual Disability ◽  
Population Based Study

scholarly journals Methodological aspects of the 1993 Pelotas (Brazil) birth cohort study

2006 ◽  
Vol 40 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Cesar Gomes Victora ◽  
Cora Luiza Pavin Araújo ◽  
Ana Maria Batista Menezes ◽  
Pedro Curi Hallal ◽  
Maria de Fátima Vieira ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Population Based ◽  
Birth Cohort Study ◽  
Southern Brazil ◽  
Population Based Study ◽  
Middle Income ◽  
Adult Disease ◽  
Middle Income Countries ◽  
Methodological Aspects

This paper describes the main methodological aspects of a cohort study, with emphasis on its recent phases, which may be relevant to investigators planning to carry out similar studies. In 1993, a population based study was launched in Pelotas, Southern Brazil. All 5,249 newborns delivered in the city's hospitals were enrolled, and sub-samples were visited at the ages of one, three and six months and of one and four years. In 2004-5 it was possible to trace 87.5% of the cohort at the age of 10-12 years. Sub-studies are addressing issues related to oral health, psychological development and mental health, body composition, and ethnography. Birth cohort studies are essential for investigating the early determinants of adult disease and nutritional status, yet few such studies are available from low and middle-income countries where these determinants may differ from those documented in more developed settings.

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