scholarly journals Late‐life social activity moderates the association between temporal lobe atrophy and episodic memory decline

2021 ◽  
Vol 17 (S10) ◽  
Author(s):  
Jihyeon Jo ◽  
Hairin Kim ◽  
Yoosik Youm ◽  
Jeanyung Chey
2017 ◽  
Vol 13 (7) ◽  
pp. P1466-P1467
Author(s):  
Anne Maass ◽  
Samuel N. Lockhart ◽  
Taylor J. Mellinger ◽  
Rachel K. Bell ◽  
Suzanne L. Baker ◽  
...  

1999 ◽  
Vol 56 (8) ◽  
pp. 961 ◽  
Author(s):  
Robert Barber ◽  
Anil Gholkar ◽  
Philip Scheltens ◽  
Clive Ballard ◽  
Ian G. McKeith ◽  
...  

2021 ◽  
pp. jech-2020-215567
Author(s):  
Yaoyue Hu ◽  
Milagros Ruiz ◽  
Martin Bobak ◽  
Pekka Martikainen

BackgroundThere is mixed evidence on the association between living arrangements and mid-late life cognition, which may be due to distinct familial arrangements and preferences between populations. To address such heterogeneity, we assessed these associations in China and England.MethodsFour-year trajectories of episodic memory scores (0–20, word recall test) by living arrangements (living with partner only, living with partner and children/grandchildren, living with no partner but with children/grandchildren, and living alone) were estimated using latent growth curve modelling for men and women aged 50+ from China (n=12 801) and England (n=10 964).ResultsAfter adjusting for baseline socioeconomic, health behaviours and health covariates, worse baseline memory was found in Chinese adults living with no partner but with children/grandchildren and in Chinese women living with partner and children/grandchildren, compared with those living with partner only. Better baseline memory was associated with living alone in English women. A faster memory decline was found in Chinese men living with no partner but with children/grandchildren (−0.122 word/year, 95% CI −0.213 to –0.031), as well as in English women living with children/grandchildren with (−0.114, 95% CI −0.180 to –0.049) or without (−0.118, 95% CI −0.209 to –0.026) a partner, and those living alone (−0.075, 95% CI −0.127 to –0.024). No differences at baseline nor over follow-up were found between English men in different living arrangements.ConclusionOverall, our findings did not confirm the protective effects of co-residence with children/grandchildren, nor the detrimental effects of living alone on mid-late life cognition in China and England.


2017 ◽  
Vol 13 (7S_Part_2) ◽  
pp. P94-P95
Author(s):  
Anne Maass ◽  
Samuel N. Lockhart ◽  
Taylor J. Mellinger ◽  
Rachel K. Bell ◽  
Suzanne L. Baker ◽  
...  

2020 ◽  
Vol 34 (6) ◽  
pp. 654-666 ◽  
Author(s):  
Erika J. Laukka ◽  
Ylva Köhncke ◽  
Goran Papenberg ◽  
Laura Fratiglioni ◽  
Lars Bäckman

2009 ◽  
Vol 29 (2) ◽  
pp. 268-276 ◽  
Author(s):  
Masaki Kondo ◽  
Satoshi Mochizuki ◽  
Mutsutaka Kobayakawa ◽  
Natsuko Tsuruya ◽  
Mitsuru Kawamura

2020 ◽  
Author(s):  
Susan L. Benear ◽  
Elizabeth A. Horwath ◽  
Emily Cowan ◽  
M. Catalina Camacho ◽  
Chi Ngo ◽  
...  

The medial temporal lobe (MTL) undergoes critical developmental change throughout childhood, which aligns with developmental changes in episodic memory. We used representational similarity analysis to compare neural pattern similarity for children and adults in hippocampus and parahippocampal cortex during naturalistic viewing of clips from the same movie or different movies. Some movies were more familiar to participants than others. Neural pattern similarity was generally lower for clips from the same movie, indicating that related content taxes pattern separation-like processes. However, children showed this effect only for movies with which they were familiar, whereas adults showed the effect consistently. These data suggest that children need more exposures to stimuli in order to show mature pattern separation processes.


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