Précis de Diagnostic chirurgical. Published under the direction of Professor Ch. Lenormant, Paris. In four volumes, 7¾ × 5¼ in. Vol. I. General, by Ch. Lenormant and J. Sénèque. Head and Neck, by P. Wilmoth. Pp. 764, with 196 illustrations. Fr. 80; bound, Fr. 105. Vol. II. Thorax, Breast, Abdominal Wall, External Genital Organs, by J. Patel. Pp. 490, with 138 illustrations. Fr. 50; bound, Fr. 70. Vol. III. Abdomen and Pelvis, by G. Ménégaux. Pp. 964, with 212 illustrations. Fr. 100; bound, Fr. 125. Vol. IV. Extremities, by J. Sénèque. Pp. 630, with 168 illustrations. Fr. 70; bound, Fr. 90. 1937. Paris : Masson et Cie

1938 ◽  
Vol 25 (100) ◽  
pp. 922-922
Keyword(s):  
Head And Neck ◽  
Abdominal Wall ◽  
External Genital Organs

scholarly journals Malignant peripheral nerve sheath tumor of anterior abdominal wall- A rare presentation

2021 ◽  
Vol 3 (3) ◽  
pp. 81-83
Author(s):  
Benny P B ◽  
T A Vasu ◽  
Illakia Selvan ◽  
Anjali Rajan
Keyword(s):  
Early Diagnosis ◽  
Peripheral Nerve ◽  
Head And Neck ◽  
Abdominal Wall ◽  
Malignant Tumors ◽  
Anterior Abdominal Wall ◽  
Nerve Sheath Tumor ◽  
Rare Presentation ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Malignant peripheral nerve sheath tumor is highly malignant tumors that occur most commonly in head and neck as well as extremities. Very rarely it seen in the retroperitoneum. When associated with neurofibromatosis, they are having a poor outcome. We present a case malignant peripheral nerve sheath tumor of anterior abdominal wall. The location and rapid increase in size of the swelling permitted early diagnosis and treatment.

scholarly journals TWO RARE CASES OF ABDOMINAL WALL METASTASES FROM HEAD AND NECK CANCER

2001 ◽  
Vol 27 (1) ◽  
pp. 265-268
Author(s):  
Tetsuo KOIWA ◽  
Jyunkichi YOKOYAMA ◽  
Sho HASHIMOTO ◽  
Kiyoto SHIGA ◽  
Sigeru SAIJO
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Abdominal Wall ◽  
Neck Cancer

Unusual Metastases to Soft Tissue of Chest and Abdominal Wall from Head and Neck Squamous Cell Carcinoma

2009 ◽  
Vol 102 (4) ◽  
pp. 444-445
Author(s):  
Yung-Sung Yeh ◽  
Chih-Fung Wu ◽  
Ming-Chen Paul Shih ◽  
Sheau-Fang Yang ◽  
Jaw-Yuan Wang
Keyword(s):  
Squamous Cell Carcinoma ◽  
Soft Tissue ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Abdominal Wall ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Unusual Metastases

Copper-dependent ATP7B up-regulation drives the resistance of TMEM16A-overexpressing head-and-neck cancer models to platinum toxicity

2019 ◽  
Vol 476 (24) ◽  
pp. 3705-3719 ◽  
Author(s):  
Avani Vyas ◽  
Umamaheswar Duvvuri ◽  
Kirill Kiselyov
Keyword(s):  
Oxidative Stress ◽  
Head And Neck ◽  
Transcriptional Activation ◽  
Platinum Resistance ◽  
Mrna Levels ◽  
Strong Positive Correlation ◽  
Platinum Compounds ◽  
Copper Chelation ◽  
Novel Approach ◽  
Cancer Models

Platinum-containing drugs such as cisplatin and carboplatin are routinely used for the treatment of many solid tumors including squamous cell carcinoma of the head and neck (SCCHN). However, SCCHN resistance to platinum compounds is well documented. The resistance to platinum has been linked to the activity of divalent transporter ATP7B, which pumps platinum from the cytoplasm into lysosomes, decreasing its concentration in the cytoplasm. Several cancer models show increased expression of ATP7B; however, the reason for such an increase is not known. Here we show a strong positive correlation between mRNA levels of TMEM16A and ATP7B in human SCCHN tumors. TMEM16A overexpression and depletion in SCCHN cell lines caused parallel changes in the ATP7B mRNA levels. The ATP7B increase in TMEM16A-overexpressing cells was reversed by suppression of NADPH oxidase 2 (NOX2), by the antioxidant N-Acetyl-Cysteine (NAC) and by copper chelation using cuprizone and bathocuproine sulphonate (BCS). Pretreatment with either chelator significantly increased cisplatin's sensitivity, particularly in the context of TMEM16A overexpression. We propose that increased oxidative stress in TMEM16A-overexpressing cells liberates the chelated copper in the cytoplasm, leading to the transcriptional activation of ATP7B expression. This, in turn, decreases the efficacy of platinum compounds by promoting their vesicular sequestration. We think that such a new explanation of the mechanism of SCCHN tumors’ platinum resistance identifies novel approach to treating these tumors.

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