Volume infusion in experimental refractory shock

1979 ◽  
Vol 66 (2) ◽  
pp. 80-83 ◽  
Author(s):  
J. A. R. Smith ◽  
J. N. Norman
Keyword(s):  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ryoung-Eun Ko ◽  
Chi Ryang Chung ◽  
Jeong Hoon Yang ◽  
Kyeongman Jeon ◽  
Gee Young Suh ◽  
...  

AbstractAlthough extracorporeal membrane oxygenation (ECMO) is increasingly utilized, only a limited level of experience has been reported in postpartum cardiopulmonary failure. Ten critically ill postpartum patients who received ECMO were included between January 2010 and December 2018 in this retrospective observational study. The main indication for ECMO support was peripartum cardiomyopathy (n = 5), followed by postpartum hemorrhage (n = 2). Nine patients initially received veno-arterial ECMO, and one patient received veno-venous ECMO. Major bleeding occurred in six patients. The median number of units of red blood cells (RBC) transfused during ECMO was 14.5 units (interquartile range 6.8–37.8 units), and most RBC transfusions occurred on the first day of ECMO. The survival-to-discharge rate was 80%. Compared to the survival outcomes in female patients of similar age who received ECMO, the survival outcomes were significantly better in the study population (56% versus 80%, P = 0.0004). Despite the high risk of major bleeding, ECMO for patients with postpartum cardiac or respiratory failure showed excellent survival outcomes. ECMO is feasible in these patients and can be carried out with good outcomes in an experienced centre.


2014 ◽  
Vol 11 (9) ◽  
pp. 1497-1499
Author(s):  
Christopher DeCotiis ◽  
Mauricio Danckers ◽  
Robert O. Roswell ◽  
Kenneth I. Berger

2018 ◽  
Vol 10 (4) ◽  
pp. 246-247 ◽  
Author(s):  
Shailesh Kumar ◽  
Devyani Thakur ◽  
Ritesh Kumar Gupta ◽  
Alka Sharma

Amlodipine is a dihydropyridine calcium channel blocker which is widely used as an anti-hypertensive drug. Amlodipine overdose has been infrequently reported with the occurrence of serious complications and even death in a few cases. We report an interesting case of a young lady who presented with refractory shock with acute kidney injury, which did not respond to therapy despite optimal fluid replacement and vasopressor support. The etiology of shock could not be ascertained and the patient was questioned again to elucidate the missing clue in the history. It was finally revealed that the patient had consumed 900 mg of amlodipine in a suicide bid, for her poor performance in academics. The targeted therapy in the form of IV calcium and hyperinsulinemia-euglycemia therapy (HIET) was started and the patient dramatically improved with shock reversal and improvement in renal function.


2017 ◽  
Vol 01 (01) ◽  
Author(s):  
El Rasheid Zakaria ◽  
Bellal Joseph ◽  
Faisal S Jehan ◽  
Muhammad Khan ◽  
Abdelrahman Algamal ◽  
...  

2016 ◽  
Vol 44 (8) ◽  
pp. 1632-1633
Author(s):  
Ian C. Gilchrist
Keyword(s):  

2008 ◽  
Vol 97 (4) ◽  
pp. 500-501 ◽  
Author(s):  
Luca Filippi ◽  
Chiara Poggi ◽  
Lisa Serafini ◽  
Patrizio Fiorini

2021 ◽  
Vol 9 ◽  
Author(s):  
Gabriella Bottari ◽  
Valerio Confalone ◽  
Nicola Cotugno ◽  
Isabella Guzzo ◽  
Salvatore Perdichizzi ◽  
...  

Background: Multisystem inflammatory syndrome in children (MIS-C) has emerged during the COVID-19 pandemic as a new SARS-CoV-2-related entity, potentially responsible for a life-threatening clinical condition associated with myocardial dysfunction and refractory shock.Case: We describe for the first time in a 14-year-old girl with severe MIS-C the potential benefit of an adjuvant therapy based on CytoSorb hemoperfusion and continuous renal replacement therapy with immunomodulatory drugs.Conclusions: We show in our case that, from the start of extracorporeal blood purification, there was a rapid and progressive restoration in cardiac function and hemodynamic parameters in association with a reduction in the most important inflammatory biomarkers (interleukin 6, interleukin 10, C-reactive protein, ferritin, and D-dimers). Additionally, for the first time, we were able to show with analysis of the sublingual microcirculation a delayed improvement in most of the important microcirculation parameters in this clinical case of MIS-C.


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