Total saponins from stems and leaves of Panax quinquefolius L. ameliorate podophyllotoxin‐induced myelosuppression and gastrointestinal toxicity

2021 ◽  
Author(s):  
Qian‐Qian Zhang ◽  
Xue‐Mei Li ◽  
Xiao‐Xin Gao ◽  
Chun‐Ran Cao ◽  
Yu‐Chi Hu ◽  
...  
Keyword(s):  
Gastrointestinal Toxicity ◽  
Panax Quinquefolius ◽  
Stems And Leaves

TISSUE DISTRIBUTION OF TRANSCRIPTS INVOLVED IN BIOSYNTHESIS OF BENZYLISOQUINOLINE ALKALOID IN MATURE PLANTS OF Argemone mexicana L. (Papaveraceae)

2018 ◽  
Vol 41 (1) ◽  
pp. 13-21 ◽  
Author(s):  
Felipe Vázquez-Flota ◽  
Jorge Rubio-Piña ◽  
Jorge Xool-Tamayo ◽  
Mariela Vergara-Olivares ◽  
Yahaira Tamayo-Ordoñez ◽  
...  
Keyword(s):  
Tissue Distribution ◽  
Transport Mechanism ◽  
Gene Products ◽  
Argemone Mexicana ◽  
Benzylisoquinoline Alkaloid ◽  
Stems And Leaves ◽  
Specific Reactions

The distribution of berberine and sanguinarine was analyzed in roots, stems and leaves of mature Argemone mexicana plants, along with that of transcripts corresponding to selected genes involved in both early biosynthetic reactions, which are common to both alkaloids, and in the late specific reactions conducting to the formation of each of them. Roots were the main sites of alkaloid accumulation, though they showed the lowest accumulation of the analyzed transcripts. Results are discussed in terms of the operation of a possible transport mechanism of alkaloids between the aerial tissues and the roots, or the occurrence of different biosynthetic alternative reactions in both parts, aerial and underground tissues, involving different gene products, yet with similar catalytic capacities.

Screening and Structures Characterization ofα-Glucosidase Inhibitors from Total Saponins of Ginseng Stems and Leaves by Ultrafiltration LC-MSn

2013 ◽  
Vol 41 (11) ◽  
pp. 1694
Author(s):  
Zhong-Mei HE ◽  
Xiao-Hui WANG ◽  
Guo-Feng LI ◽  
Jia-Ming SUN ◽  
He YANG ◽  
...  
Keyword(s):  
Glucosidase Inhibitors ◽  
Stems And Leaves

Aristolochia triangularis Cham. stems and leaves essential oils and their antimicrobial and antimycobacterial effects

2020 ◽  
Vol 10 ◽  
Author(s):  
Ionara I. Dalcol ◽  
Alessandra O. Pereira ◽  
Luisa H. Paz ◽  
Gabriela Benetti ◽  
Fallon S. Siqueira ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oils ◽  
Candida Glabrata ◽  
Skin Diseases ◽  
Enterobacter Aerogenes ◽  
Gas Chromatography Mass Spectrometry ◽  
Moderate Activity ◽  
Circulatory System Diseases ◽  
Germacrene D ◽  
Stems And Leaves

Background: Aristolochia triangularis Cham., popularly known as the "cipó-mil-homens", "angelicó" and "ypê-mi", is applied for the treatment of wounds, skin diseases (6,7), digestive and circulatory system diseases as an antipyretic and for malaria fever. Objective: In this work we investigated the chemical composition, the antimicrobial and antimycobacterial activities of the essential oils (EOs) extracted from A. triangularis fresh stems and leaves collected in Southern Brazil. Methods: Fresh stems and fresh leaves of Aristolochia triangularis Cham. were separately subjected to hydrodistillation using a Clevenger-type apparatus. The chemical composition of the essential oils (EOs) were analyzed by gas chromatography/mass spectrometry (GC/MS). The oil samples were evaluated for their antimycobacterial, antibacterial and antifungal activities against twenty-four microorganisms. Results: Hydrodistillation of fresh stems and leaves of A. triangularis resulted in 0.16% (w/w) and 0.37% (w/w) respectively of light-yellow oils. Germacrene D is found in 13.2 - 13.5% in both EOs. The constituent most abundant in the stems EO (19.18%) was the oxygenated diterpene ent-Kaur-16-en-19-al (10), along with E-nerolidol (17.89%). The main constituents of the leaves EO were bicyclogermacrene (24.79%), β-elemene (11.30%), E-caryophyllene (10.40%) and germacrene A (9.42%), in addition to the previously mentioned germacrene D. The stems and leaves EOs showed capacity to inhibit the Gram-negative Enterobacter aerogenes and the stems EO capacity to inhibit Staphylococcus aureus, with MIC values of 31.2 µg/mL. S. aureus was moderately sensitive to leaves EO, while stems EO displayed moderate activity against Enterococcus faecalis and Salmonella typhimurium (MIC values of 62.5 µg/mL). Candida glabrata was highly susceptible to both EOs (MIC values < 3.9 µg/mL). The EOs showed moderate potential to inhibit the growth of Cryptococcus gatti and Cryptococcus neoformans (MICs of 62.5 μg/mL). Conclusion: The A. triangularis essential oils from stems and leaves displayed capacity to inhibit Enterobacter aerogenes (MIC values of 31.2 µg/mL) and high antifungal effect against Candida glabrata (MIC values of <3.9 µg/mL). Mycobacterium massiliense and M. abscessus were susceptible to the leaves EO, with MICs of 39.06 μg/mL. These results showed the A. triangularis essential oils potential as antifungal and antimycobacterial to be used in the development of new antibiotic.

scholarly journals Cell wall proteomic datasets of stems and leaves of Brachypodium distachyon

Data in Brief ◽  
2021 ◽  
Vol 35 ◽  
pp. 106818
Author(s):  
Thibaut Douché ◽  
Benoît Valot ◽  
Thierry Balliau ◽  
Hélène San Clemente ◽  
Michel Zivy ◽  
...  
Keyword(s):  
Cell Wall ◽  
Brachypodium Distachyon ◽  
Stems And Leaves

Biotransformation of ginsenoside Rc to Rd by endophytic bacterium Bacillus sp. G9y isolated from Panax quinquefolius

2021 ◽  
Author(s):  
Chen Zhang ◽  
Yanyan Xu ◽  
Mengmeng Gu ◽  
Zhenzhen Liu ◽  
Jingyuan Zhang ◽  
...  
Keyword(s):  
Endophytic Bacterium ◽  
Panax Quinquefolius ◽  
Bacillus Sp ◽  
Bacterium Bacillus ◽  
Ginsenoside Rc
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