A comparative study of the effects of the diamine oxidase inhibitor aminoguanidine, with or without dietary restriction, on the nucleic acid and protein composition of cardiac and type I and type II skeletal muscles of the rat

1991 ◽  
Vol 9 (3) ◽  
pp. 201-207
Author(s):  
Tahir Siddiq ◽  
Victor R Preedy
Keyword(s):  
Nucleic Acid ◽  
Comparative Study ◽  
Dietary Restriction ◽  
Skeletal Muscles ◽  
Diamine Oxidase ◽  
Protein Composition ◽  
Oxidase Inhibitor ◽  
Type I ◽  
Type Ii

scholarly journals A Locomotor Disorder Clinically Similar to Spastic Paresis in an Adult Friesian Bull

1980 ◽  
Vol 17 (3) ◽  
pp. 305-315 ◽  
Author(s):  
R. Bradley ◽  
W.V.S. Wueratne
Keyword(s):  
Skeletal Muscles ◽  
Hind Limb ◽  
Type I ◽  
Type Ii ◽  
Hind Limbs ◽  
Type Ii Cell ◽  
Spastic Paresis ◽  
Flexor Digitorum ◽  
I Cells ◽  
Severe Type

A 5-year-old Friesian stud bull developed a progressive locomotor disorder on return to stud after a period of rest. He had defects in conformation exacerbated by poor condition. The hind limbs were excessively straight. When he stood or moved, the Achilles tendons and their associated muscles were rigid. The disorder clinically resembled spastic paresis of calves. Necropsy showed a degenerative arthropathy in all hind limb joints below the hip. Lesions were also in tendons and skeletal muscles. The M. flexor digitorum superficialis had severe type II cell atrophy with many ring. lobulated and moth-eaten type I cells.

Elevated endothelial-cell-stimulating angiogenic factor activity in rodent glycolytic skeletal muscles

1991 ◽  
Vol 81 (2) ◽  
pp. 267-270 ◽  
Author(s):  
R. G. Cooper ◽  
C. M. Taylor ◽  
J. J. Choo ◽  
J. B. Weiss
Keyword(s):  
Endothelial Cell ◽  
Skeletal Muscles ◽  
Extensor Digitorum Longus ◽  
Capillary Density ◽  
Extensor Digitorum ◽  
Angiogenic Factor ◽  
Type I ◽  
Type Ii ◽  
Factor Activity ◽  
Angiogenic Activity

1. Capillary density is greater in skeletal muscles comprised of predominantly oxidative (type I) fibres than in those comprised of mainly glycolytic (type II) fibres. In order to investigate further the angiogenic mechanisms involved in muscle capillarization, endothelial-cellstimulating angiogenic factor activities in various rodent skeletal muscles were compared. 2. Eleven untrained adult male Wistar rats were killed and the predominantly oxidative (type I) muscles, soleus and heart, the predominantly glycolytic (type II) muscle, extensor digitorum longus, and the mixed-fibre muscle, gastrocnemius, were removed. Each sample was separately homogenized and centrifuged and the supernatants were diafiltered to isolate the low-molecular-mass fraction containing endothelial-cell-stimulating angiogenic activity. This was assayed for its ability to activate latent collagenase and was expressed as units, where 1 unit represents the percentage activation of the enzyme h−1 (mg of protein in the supernatant)−1. 3. The results (medians and ranges) demonstrated significantly greater endothelial-cell-stimulating angiogenic factor activity in extensor digitorum longus muscle (2.14 units, 0.62–2.87 units, n = 13) than in soleus (0.82 units, 0.59–1.79 units, n = 15), gastrocnemius (0.34 units, 0.28–0.40 units, n = 4) or heart (0.43 units, 0.16–0.52 units, n = 11) (P< 0.01 for each) muscle. 4. These findings suggest that endothelial-cell-stimulating angiogenic activity in muscle is either inversely or not related to the local capillary density, which may be at or near a maximum in physiologically contracting, predominantly oxidative muscles.

scholarly journals Isolation of Type I and Type II Pericytes from Mouse Skeletal Muscles

10.3791/55904 ◽  
2017 ◽  
Author(s):  
Abhijit Nirwane ◽  
Jyoti Gautam ◽  
Yao Yao
Keyword(s):  
Skeletal Muscles ◽  
Type I ◽  
Type Ii

scholarly journals A comparative study of type I and type II tryparedoxin peroxidases inLeishmania major

FEBS Journal ◽  
2007 ◽  
Vol 274 (21) ◽  
pp. 5643-5658 ◽  
Author(s):  
Janine König ◽  
Alan H. Fairlamb
Keyword(s):  
Comparative Study ◽  
Type I ◽  
Type Ii

scholarly journals A comparative study of the gut microbiome in Egyptian patients with Type I and Type II diabetes

PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0238764
Author(s):  
Sahar Radwan ◽  
Darby Gilfillan ◽  
Bridget Eklund ◽  
Hend M. Radwan ◽  
Nagwan G. El Menofy ◽  
...  
Keyword(s):  
Comparative Study ◽  
Gut Microbiome ◽  
Type Ii Diabetes ◽  
Type I ◽  
Type Ii ◽  
Egyptian Patients

Comparative study of photoluminescence for type-I InAs/GaAs0.89Sb0.11 and type-II InAs/GaAs0.85Sb0.15 quantum dots

2019 ◽  
Vol 98 ◽  
pp. 109479 ◽  
Author(s):  
Chuan Zhou ◽  
Baolai Liang ◽  
Jingtao Liu ◽  
Ying Wang ◽  
Yingnan Guo ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Comparative Study ◽  
Type I ◽  
Type Ii

Pathological Features of Reinnervated Skeletal Muscles Following Crush Injury of the Sciatic Nerve in Ob/ob Mice

2020 ◽  
Author(s):  
Takahiro Asano ◽  
Masaya Tsujii ◽  
Takahiro Iino ◽  
Kazuya Odake ◽  
Akihiro Sudo
Keyword(s):  
Skeletal Muscles ◽  
Histological Analysis ◽  
Type I ◽  
Type Ii ◽  
Collagen Deposition ◽  
Nerve Crush ◽  
Cross Sectional ◽  
Wet Weight ◽  
Gastrocnemius Muscles ◽  
Type Ii Fibers

Abstract Background: Obesity is a factor for insufficient improvement of motor function for peripheral nerve disorders. The aims of this study were to evaluate the skeletal muscles during denervation and re-innervation following nerve crush injury in ob/ob mice. Methods: Experiments were performed on the skeletal muscles of the hindlimbs in 20 male leptin-deficient (ob/ob) mice and control mice. Firstly, the characteristics of the gastrocnemius muscles in the mice were evaluated by histological analysis, immunohistological analysis, and Sircol-collagen assay after measurement of body weight and wet weight of the skeletal muscles and by walking tracking analysis. In the histological analysis, nicotinamide adenine dinucleotide tetrazolium reductase (NADH-TR) staining, oil red O staining, and Picro-sirius red staining were performed to assess the type of myofibers, lipid accumulation, and collagen deposition, respectively. Then, the models for denervation and re-innervation were made by crushing the sciatic nerves with smooth forceps. The same assessments were performed on the skeletal muscles of nerve crush models.Results: The wet weight of the gastrocnemius muscles was significantly less in the ob/ob mice than the control mice, whereas body weight was significantly more. Histological analyses demonstrated a smaller cross-sectional area of type II fibers and increase of type I fiber grouping of the skeletal muscles in the ob/ob mice. In addition, there was excessive deposition of lipids and collagens between the myofibers. Following the nerve injury, the recovery of motor function was equal between both groups, while the cross-sectional area of type II fibers was significantly smaller in the ob/ob mice than the control mice at 4 weeks. Furthermore, the denervated muscles showed an increase in collagen deposition to the area of intermyofibers, which were predominant in the ob/ob mice after the nerve injury.Conclusions: The present study showed an increase of collagen deposition, delayed recovery of type II myofibers, and type I fiber grouping during denervation and re-innervation in the skeletal muscles of ob/ob mice. We suggest through these findings that the reduction of contractile force could be one of causes of insufficient improvement in peripheral nerve disorders of obese individuals.

scholarly journals A comparative study for tension-reducing effect of Type I and Type II keystone perforator island flap in the human back

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Chi Sun Yoon ◽  
Yu Taek Kong ◽  
Soo Yeon Lim ◽  
Junekyu Kim ◽  
Hyun Woo Shin ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Comparative Study ◽  
Reconstructive Surgery ◽  
Island Flap ◽  
Type I ◽  
Type Ii ◽  
Complete Excision ◽  
Tension Change ◽  
Before And After ◽  
The Mean

AbstractThe keystone perforator island flap (KPIF) is popular in reconstructive surgery. However, despite its versatility, its biomechanical effectiveness is unclear. We present our experience of KPIF reconstruction in the human back and evaluate the tension-reducing effect of the KPIF. Between September 2019 and August 2020, 17 patients (51.82 ± 14.72 years) underwent KPIF reconstruction for back defects. In all cases, we measured wound tension at the defect and donor sites before and after KPIF reconstruction using a tensiometer. All defects occurred after complete excision of complicated epidermoid cysts and debridement of surrounding tissues. The defects were successfully covered with Type IIA KPIFs. All flaps survived, and there were no significant postoperative complications. The mean “tension change at the defect after Type I KPIF” and “tension change at the defect after Type II KPIF” were − 2.97 ± 0.22 N and − 5.59 ± 0.41 N, respectively, (P < 0.001). The mean “rate of tension change at the defect after Type I KPIF” and “rate of tension change at the defect after Type II KPIF” were − 36.54 ± 1.89% and − 67.98 ± 1.63%, respectively, (P < 0.001). Our findings confirm the stepwise tension-reducing effect of KPIF and clarify the biomechanics of this flap.

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