How does multiple-micronutrient supplementation for pregnant women affect infant outcomes?

2019 ◽  
Author(s):  
Sera Tort ◽  
Juliana Ester Martin
Keyword(s):  
Pregnant Women ◽  
Micronutrient Supplementation ◽  
Infant Outcomes ◽  
Multiple Micronutrient

scholarly journals Acceptability of multiple micronutrient supplements by pregnant and lactating women in Mali

2005 ◽  
Vol 8 (1) ◽  
pp. 33-37 ◽  
Author(s):  
Víctor M Aguayo ◽  
Diakalia Koné ◽  
Sory Ibrahim Bamba ◽  
Baba Diallo ◽  
Yacouba Sidibé ◽  
...  
Keyword(s):  
Folic Acid ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Folic Acid Supplementation ◽  
Effective Control ◽  
Micronutrient Supplementation ◽  
Acid Supplementation ◽  
Women’S Perceptions ◽  
Multiple Micronutrient ◽  
Iron And Folic Acid

AbstractBackground:In Mali, an estimated 73% of pregnant women are anaemic largely due to iron deficiency. National policy recommends women to take iron and folic acid supplements daily from first prenatal contact until 3 months postpartum. However, many pregnant women in Mali could benefit from multiple micronutrient supplements.Objective:To assess pregnant women's acceptability of and adherence to a daily multiple micronutrient supplementation scheme compared with the current daily iron and folic acid supplementation scheme.Design:Seventy pregnant women were allocated to either the daily multiple micronutrient or daily iron and folic acid supplementation scheme. Women started receiving supplements at the end of the first trimester of pregnancy until delivery and throughout the first 3 months postpartum.Results:No significant differences were observed between comparison groups with respect to women's perceptions about supplement size, colour, taste or flavour. Adherence to the multiple micronutrient supplementation scheme was better (257.5±20.9 tablets; average adherence 95.4%) than that to the iron and folic acid supplementation scheme (238.5±32.7 tablets; average adherence 92.2% P = 0.008) although both were very good, as were women's perceptions about the benefits of micronutrient supplements to their health and that of their newborns.Conclusion:Malian women adhere to prenatal/postpartum micronutrient supplementation – no matter what supplement is chosen – when access to supplements is guaranteed and when they are provided with minimum, consistent and easily understandable information and counselling, indicating that these are key elements to ensure effective programmes. These findings, together with those of the global research agenda on the efficacy of multiple micronutrient supplements for pregnant women, will inform policy development in Mali for the effective control of iron deficiency and iron-deficiency anaemia in pregnant women.

scholarly journals Multiple micronutrient supplementation and dietary energy intake in pregnant women

2007 ◽  
Vol 49 (3) ◽  
Author(s):  
María de Lourdes Flores ◽  
Lynnette M Neufeld ◽  
Teresa González-Cossío ◽  
Juan Rivera ◽  
Reynaldo Martorell ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Energy Intake ◽  
Dietary Energy ◽  
Micronutrient Supplementation ◽  
Dietary Energy Intake ◽  
Multiple Micronutrient

scholarly journals Multiple Micronutrient Supplementation During Pregnancy: Evidence Review (P10-092-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Megan Bourassa ◽  
Gilles Bergeron ◽  
Filomena Gomes
Keyword(s):  
Pregnant Women ◽  
Task Force ◽  
Meta Analysis ◽  
Cochrane Review ◽  
Cost Effective ◽  
Standard Of Care ◽  
Protective Effects ◽  
Micronutrient Supplementation ◽  
Micronutrient Deficiencies ◽  
Multiple Micronutrient

Abstract Objectives Insufficient pre-pregnancy intakes of micronutrients, combined with increased nutrient demands during pregnancy often result in maternal micronutrient deficiencies that affect the health of the mother and the development of the fetus. WHO currently recommends iron and folic acid (IFA) supplementation as standard of care for pregnant women, but recognizes that multiple micronutrient supplementation (MMS) may improve pregnancy outcomes under given conditions. New evidence on the effect of MMS compared to IFA during pregnancy was reviewed to develop guidance for countries that may want to consider providing MMS to pregnant women. Methods An expert task force was assembled by the Sackler Institute to assess the data from trials comparing MMS to IFA, the risks of reaching the upper intake levels with MMS, the risk of harm to pregnant women or their infants, and to do a cost-effectiveness analysis (CEA) of MMS compared to IFA. Recent data from a Cochrane review (CR) and an Individual Patient Data meta-analysis (IDP) were assessed. Results Both reviews, predominantly using data from low and middle income countries (LMIC), demonstrated improved pregnancy and birth outcomes among women receiving MMS instead of IFA, including a lower risk of low birth weight (RR 0.88 (95% CI 0.85–0.91) in the CR; RR 0.88 (95% CI 0.85–0.90) in the IPD) and of small for gestational age births (RR 0.92 (95% CI 0.86–0.98) in the CR and RR 0.97 (95% CI 0.96–0.99) in the IDP). The IDP identified further beneficial effects of MMS vs. IFA on preterm birth (RR 0.92 (95% CI 0.88–0.95)) and stillbirth (RR 0.92 (95% CI 0.86–0.99)). Larger protective effects of MMS were observed in subgroups of anemic and underweight women, two prevalent conditions in LMIC. The CEA also supported the transition from IFA to MMS. Conclusions Pregnant women in LMICs and their infants could benefit from MMS over IFA during pregnancy, as a cost-effective intervention. This presentation will discuss the approach used by the expert task force, its conclusions, as well as a framework to help LMIC decide on which program to support, and ongoing efforts to pilot the adoption of MMS in sample countries. Funding Sources Bill & Melinda Gates Foundation.

scholarly journals Effect of Multiple Micronutrient Supplementation on Pregnancy and Infant Outcomes: A Systematic Review

2012 ◽  
Vol 26 ◽  
pp. 153-167 ◽  
Author(s):  
Usha Ramakrishnan ◽  
Frederick Kobina Grant ◽  
Tamar Goldenberg ◽  
Vinh Bui ◽  
Aamer Imdad ◽  
...  
Keyword(s):  
Systematic Review ◽  
Micronutrient Supplementation ◽  
Infant Outcomes ◽  
Multiple Micronutrient

scholarly journals Maternal adherence to micronutrient supplementation before and during pregnancy in Northwest China: a large-scale population-based cross-sectional survey

BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e028843 ◽  
Author(s):  
Danmeng Liu ◽  
Yue Cheng ◽  
Shaonong Dang ◽  
Duolao Wang ◽  
Yaling Zhao ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Large Scale ◽  
Northwest China ◽  
Population Based ◽  
Shaanxi Province ◽  
Micronutrient Supplementation ◽  
Cross Sectional Survey ◽  
Start Time ◽  
Cross Sectional ◽  
Scale Population

ObjectivesTo report the situation of maternal micronutrient supplementation before and during pregnancy in Northwest China and to examine the rates of and factors related to the adherence to micronutrient supplementation among pregnant women in this region, where dietary micronutrient intake is commonly insufficient.DesignA large-scale population-based cross-sectional survey.SettingTwenty counties and ten districts of Shaanxi Province.ParticipantsA sample of 30 027 women were selected using a stratified multistage random sampling method. A total of 28 678 women were chosen for the final analysis after excluding those who did not provide clear information about nutritional supplementation before and during pregnancy.Main outcome measuresMaternal adherence to micronutrient supplementation (high and low) were the outcomes. They were determined by the start time and duration of use according to Chinese guidelines (for folic acid (FA) supplements) and WHO recommendations (for iron, calcium and multiple-micronutrient (MMN) supplements).ResultsIn total, 83.9% of women took at least one kind of micronutrient supplement before or during pregnancy. FA (67.6%) and calcium (57.5%) were the primarily used micronutrient supplements; few participants used MMN (14.0%) or iron (5.4%). Adherence to supplementation of all micronutrients was low (7.4% for FA, 0.6% for iron, 11.7% for calcium and 2.7% for MMN). Higher educational levels, higher income levels, urban residence and better antenatal care (including pregnancy consultation and a higher frequency of antenatal visits) were associated with high adherence to micronutrient supplementation.ConclusionMaternal micronutrient supplementation before and during pregnancy in Northwest China was way below standards recommended by the Chinese guidelines or WHO. Targeted health education and future nutritional guidelines are suggested to improve this situation, especially in pregnant women with disadvantaged sociodemographic conditions.

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