Label-Free Fluorescent Probing of G-Quadruplex Formation and Real-Time Monitoring of DNA Folding by a Quaternized Tetraphenylethene Salt with Aggregation-Induced Emission Characteristics

2008 ◽  
Vol 14 (21) ◽  
pp. 6428-6437 ◽  
Author(s):  
Yuning Hong ◽  
Matthias Häußler ◽  
Jacky W. Y. Lam ◽  
Zhen Li ◽  
King Keung Sin ◽  
...  
Keyword(s):  
Real Time ◽  
Emission Characteristics ◽  
Label Free ◽  
Real Time Monitoring ◽  
Aggregation Induced Emission ◽  
Dna Folding ◽  
G Quadruplex ◽  
Quadruplex Formation

scholarly journals Real-Time Monitoring of G-Quadruplex Formation during Transcription

2016 ◽  
Vol 88 (4) ◽  
pp. 1984-1989 ◽  
Author(s):  
Tamaki Endoh ◽  
Ambadas B. Rode ◽  
Shuntaro Takahashi ◽  
Yuka Kataoka ◽  
Masayasu Kuwahara ◽  
...  
Keyword(s):  
Real Time ◽  
Real Time Monitoring ◽  
G Quadruplex ◽  
Quadruplex Formation

Label-free and real time monitoring of adipocyte differentiation by surface infrared spectroscopy

2013 ◽  
Vol 176 ◽  
pp. 1176-1182 ◽  
Author(s):  
Yuki Aonuma ◽  
Yasuhiko Kondo ◽  
Ayumi Hirano-Iwata ◽  
Atena Nishikawa ◽  
Yasuo Shinohara ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Real Time ◽  
Adipocyte Differentiation ◽  
Label Free ◽  
Real Time Monitoring

Label-free optical biosensor for real-time monitoring the cytotoxicity of xenobiotics: A proof of principle study on glyphosate

2018 ◽  
Vol 351 ◽  
pp. 80-89 ◽  
Author(s):  
Eniko Farkas ◽  
Andras Szekacs ◽  
Boglarka Kovacs ◽  
Marianna Olah ◽  
Robert Horvath ◽  
...  
Keyword(s):  
Real Time ◽  
Optical Biosensor ◽  
Label Free ◽  
Real Time Monitoring ◽  
Proof Of Principle

Ultrabright Organic Dots with Aggregation-Induced Emission Characteristics for Real-Time Two-Photon Intravital Vasculature Imaging

2013 ◽  
Vol 25 (42) ◽  
pp. 6083-6088 ◽  
Author(s):  
Dan Ding ◽  
Chi Ching Goh ◽  
Guangxue Feng ◽  
Zujin Zhao ◽  
Jie Liu ◽  
...  
Keyword(s):  
Real Time ◽  
Emission Characteristics ◽  
Aggregation Induced Emission ◽  
Two Photon

scholarly journals Real-Time Monitoring of Biotinylated Molecules Detection Dynamics in Nanoporous Anodic Alumina for Bio-Sensing

Nanomaterials ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 478 ◽  
Author(s):  
Laura Pol ◽  
Chris Eckstein ◽  
Laura Acosta ◽  
Elisabet Xifré-Pérez ◽  
Josep Ferré-Borrull ◽  
...  
Keyword(s):  
Surface Modification ◽  
Real Time ◽  
Anodic Alumina ◽  
Label Free ◽  
Real Time Monitoring ◽  
Helpful Tool ◽  
Nanoporous Anodic Alumina ◽  
Efficient Detection ◽  
Sensitivity And Selectivity ◽  
Molecule Model

The chemical modification, or functionalization, of the surfaces of nanomaterials is a key step to achieve biosensors with the best sensitivity and selectivity. The surface modification of biosensors usually comprises several modification steps that have to be optimized. Real-time monitoring of all the reactions taking place during such modification steps can be a highly helpful tool for optimization. In this work, we propose nanoporous anodic alumina (NAA) functionalized with the streptavidin-biotin complex as a platform towards label-free biosensors. Using reflective interferometric spectroscopy (RIfS), the streptavidin-biotin complex formation, using biotinylated thrombin as a molecule model, was monitored in real-time. The study compared the performance of different NAA pore sizes in order to achieve the highest response. Furthermore, the optimal streptavidin concentration that enabled the efficient detection of the biotinylated thrombin attachment was estimated. Finally, the ability of the NAA-RIfS system to quantify the concentration of biotinylated thrombin was evaluated. This study provides an optimized characterization method to monitor the chemical reactions that take place during the biotinylated molecules attachment within the NAA pores.

Label-free and sensitive detection of coralyne and heparin based on target-induced G-quadruplex formation

2019 ◽  
Vol 11 (10) ◽  
pp. 1331-1337 ◽  
Author(s):  
Mingjian Chen ◽  
Changbei Ma ◽  
Han Zhao ◽  
Kemin Wang
Keyword(s):  
Detection Method ◽  
Sensitive Detection ◽  
Label Free ◽  
G Quadruplex ◽  
Quadruplex Formation

Herein we propose a label-free and sensitive detection method for coralyne and heparin, based on utilizing the complex of adenosine16 (A16) and coralyne to induce the formation of a G-quadruplex scaffold.

Real time monitoring and label free creatinine detection with artificial receptors

2019 ◽  
Vol 244 ◽  
pp. 6-11 ◽  
Author(s):  
Aykut Arif Topçu ◽  
Erdoğan Özgür ◽  
Fatma Yılmaz ◽  
Nilay Bereli ◽  
Adil Denizli
Keyword(s):  
Real Time ◽  
Label Free ◽  
Real Time Monitoring ◽  
Artificial Receptors
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