Designed Synthesis of Lipid-Coated Polyacrylic Acid/Calcium Phosphate Nanoparticles as Dual pH-Responsive Drug-Delivery Vehicles for Cancer Chemotherapy

2017 ◽  
Vol 23 (27) ◽  
pp. 6586-6595 ◽  
Author(s):  
Xin Wang ◽  
Manjie Zhang ◽  
Lingyu Zhang ◽  
Lu Li ◽  
Shengnan Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Calcium Phosphate ◽  
Cancer Chemotherapy ◽  
Polyacrylic Acid ◽  
Ph Responsive ◽  
Drug Delivery Vehicles ◽  
Calcium Phosphate Nanoparticles ◽  
Delivery Vehicles ◽  
Designed Synthesis

Preparation of PEG Functionalized Nanoparticles for Drug Delivery to Cancer Cells

2014 ◽  
Vol 893 ◽  
pp. 194-197
Author(s):  
Yan Liu ◽  
Jie Ren ◽  
Jun Zhao Leng ◽  
Jian Bo Li ◽  
Li Deng
Keyword(s):  
Drug Delivery ◽  
Polyethylene Glycol ◽  
Calcium Phosphate ◽  
Zeta Potential ◽  
Cellular Uptake ◽  
Physiological Solution ◽  
Ph Responsive ◽  
Functionalized Nanoparticles ◽  
Calcium Phosphate Nanoparticles ◽  
Reverse Microemulsion Method

Nanosized calcium phosphate was prepared by a reverse microemulsion method, with a 20~40 nm diameter, which is pH-responsive, nontoxic and colloidally stable in physiological solution. Polyethylene glycol modified calcium phosphate nanoparticles shifted the zeta potential to a neutral charge, which prolonged the nanoparticle circulation time and increased cellular uptake efficacy to targeted cells. The PEG-functionalized nanoparticles exhibit a great potential for efficaciously delivering hydrophobic anticancer drug, such as paclitaxel, to cells and tumors.

scholarly journals Facile synthesis of Prussian blue nanoparticles as pH-responsive drug carriers for combined photothermal-chemo treatment of cancer

RSC Advances ◽  
2017 ◽  
Vol 7 (1) ◽  
pp. 248-255 ◽  
Author(s):  
Huajian Chen ◽  
Yan Ma ◽  
Xianwen Wang ◽  
Xiaoyi Wu ◽  
Zhengbao Zha
Keyword(s):  
Drug Delivery ◽  
Prussian Blue ◽  
Cancer Cells ◽  
Drug Carriers ◽  
High Efficacy ◽  
Ph Responsive ◽  
Facile Synthesis ◽  
Drug Delivery Vehicles ◽  
Prussian Blue Nanoparticles ◽  
Delivery Vehicles

Multifunctional PEGylated PB-DOX NPs with a lipid-PEG shell were developed as a gram-scale manner and used as novel pH-responsive drug delivery vehicles for combined photothermal-chemo treatment of cancer cells with high efficacy.

Fe3O4@carbon@zeolitic imidazolate framework-8 nanoparticles as multifunctional pH-responsive drug delivery vehicles for tumor therapy in vivo

2015 ◽  
Vol 3 (46) ◽  
pp. 9033-9042 ◽  
Author(s):  
Mengni He ◽  
Jiajia Zhou ◽  
Jian Chen ◽  
Fangcai Zheng ◽  
Dongdong Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Tumor Therapy ◽  
Controlled Drug Release ◽  
Ph Responsive ◽  
Zeolitic Imidazolate Framework ◽  
Drug Delivery Vehicles ◽  
Delivery Vehicles

Controlled drug release is a promising approach for cancer therapy due to its merits of reduced systemic toxicity and enhanced antitumor efficacy.

Facile one-pot synthesis of carbon/calcium phosphate/Fe3O4 composite nanoparticles for simultaneous imaging and pH/NIR-responsive drug delivery

2016 ◽  
Vol 52 (74) ◽  
pp. 11068-11071 ◽  
Author(s):  
Mingyu Gou ◽  
Shengnan Li ◽  
Lingyu Zhang ◽  
Lu Li ◽  
Chungang Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Calcium Phosphate ◽  
Photothermal Therapy ◽  
Composite Nanoparticles ◽  
One Pot ◽  
Drug Delivery Vehicles ◽  
Simultaneous Imaging ◽  
One Pot Synthesis ◽  
Delivery Vehicles

We report herein a facile one-pot synthesis of carbon/calcium phosphate/Fe3O4 composite nanoparticles, which were employed as pH/NIR-responsive drug delivery vehicles for simultaneous MRI and chemo-photothermal therapy.

Phosphorylcholine-Based pH-Responsive Diblock Copolymer Micelles as Drug Delivery Vehicles:  Light Scattering, Electron Microscopy, and Fluorescence Experiments

2006 ◽  
Vol 7 (3) ◽  
pp. 817-828 ◽  
Author(s):  
Cristiano Giacomelli ◽  
Lucile Le Men ◽  
Redouane Borsali ◽  
Joséphine Lai-Kee-Him ◽  
Alain Brisson ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Drug Delivery ◽  
Light Scattering ◽  
Diblock Copolymer ◽  
Ph Responsive ◽  
Drug Delivery Vehicles ◽  
Delivery Vehicles ◽  
Copolymer Micelles
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