ChemInform Abstract: THE SELECTIVE EXTRACTION AND DETERMINATION OF URANIUM USING DIPHENYL ACETIC ACID

Background: Curcumin is a major ingredient in turmeric (Curcuma longa L., Zingiberaceae), which has important activities such as anti-tumor, anti-inflammatory, antioxidant, anti-ischemia, protection of gastric mucosa etc,. Curcumin can be considered as a biological marker of turmeric and turmeric products. Objectives: Developing an HPLC method for quantification of curcumin in turmeric powder and turmeric - honey ball pills; applying this method for products on the market. Materials and methods: turmeric powder and turmeric - honey ball pills collected in Thua Thien Hue province. After optimization process, the method was validated and applied to evaluate the content of curcumin. Results: The chromatography analysis was performed with: Zorbaz Eclipse XDB-C18 (150 × 4.6 nm; 5 µm); Mobile phase: acetonitril: 2% acetic acid (45:55), Flow rate was kept constant at 1.0 ml/min; Detector PDA (420 nm). The method was validated for the HPLC system compatibility, specificity, linearity range, precision and accuracy; the recovery greater than 98%. Conclusion: The developed HPLC method can determine curcumin in turmeric powder and turmeric - honey ball pills. Key words: Curcumin, turmeric powder, turmeric-honey ball pills, quantitative determination, HPLC

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HPLC-UV Method for Determination of Famotidine from Pharmaceutical Products

Revista de Chimie ◽

10.37358/rc.18.2.6093 ◽

2018 ◽

Vol 69 (2) ◽

pp. 297-299

Author(s):

Adriana Nita ◽

Delia Mirela Tit ◽

Lucian Copolovici ◽

Carmen Elena Melinte (Frunzulica) ◽

Dana Maria Copolovici ◽

...

Keyword(s):

Acetic Acid ◽

Quantitative Analysis ◽

Linear Response ◽

Mobile Phase ◽

Acetic Acid Solution ◽

Pharmaceutical Products ◽

Quantification Limit ◽

Validation Parameters ◽

Hplc Analyses

The aim of this study was to develop and validate a rapid, accurate, and exact method for the quantitative determination of famotidine in pharmaceutical products. The HPLC analyses were performed by using a mobile phase containing methanol:1% acetic acid solution=30:7 (v/v), at a flow rate of 0.4 mL/min.The total time of the method was 10 min, and the retention time of famotidine was 4.16 min. The detection was evaluated at l=267 nm. The method has been validated by using different validation parameters. The linear response of the detector for famotidine peak area was observed at concentrations ranging from 0.1 to 0.0001 mg mL-1 , resulting in a correlation coefficient of 0.99998. The values of the detection limit and of the quantification limit are 0.00048 mg mL-1 and 0.00148 mg mL-1, respectively. The method proposed allowed accurate (with a relative error of less than 2%) and precise (RSD values less than 2.0%) determination of famotidine content in pharmaceutical products and can be used for its rapid quantitative analysis.

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Selective Extraction and Determination of Citrinin in Rye Samples by a Molecularly Imprinted Polymer (MIP) Using Reversible Addition Fragmentation Chain Transfer Precipitation Polymerization (RAFTPP) with High-Performance Liquid Chromatography (HPLC) Detection

Analytical Letters ◽

10.1080/00032719.2021.1892125 ◽

2021 ◽

pp. 1-12

Author(s):

İsmet Meydan ◽

Mustafa Bilici ◽

Eylem Turan ◽

Adem Zengin

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Molecularly Imprinted Polymer ◽

High Performance ◽

Chain Transfer ◽

Selective Extraction ◽

Imprinted Polymer ◽

Molecularly Imprinted ◽

Reversible Addition

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Selective electromembrane extraction and sensitive colorimetric detection of copper(II)

Zeitschrift für Physikalische Chemie ◽

10.1515/zpch-2020-1761 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Wajid Ali Khan ◽

Muhammad Balal Arain ◽

Hashmat Bibi ◽

Mustafa Tuzen ◽

Nasrullah Shah ◽

...

Keyword(s):

Applied Voltage ◽

Colorimetric Detection ◽

Environmental Water ◽

Selective Extraction ◽

Effective Parameters ◽

Relative Standard ◽

Electromembrane Extraction ◽

Optimized Conditions ◽

Donor Phase

AbstractIn this study, an extremely effective electromembrane extraction (EME) method was developed for the selective extraction of Cu(II) followed by Red-Green-Blue (RGB) detection. The effective parameters optimized for the extraction efficiency of EME include applied voltage, extraction time, supported liquid membrane (SLM) composition, pH of acceptor/donor phases, and stirring rate. Under optimized conditions, Cu(II) was extracted from a 3 mL aqueous donor phase to 8 µL of 100 mM HCl acceptor solution through 1-octanol SLM using an applied voltage of 50 V for 15 min. The proposed method provides a working range of 0.1–0.75 µg·mL−1 with 0.03 µg·mL−1 limit for detection. Finally, the developed technique was applied to different environmental water samples for monitoring environmental pollution. Obtained relative recoveries were within the range of 93–106%. The relative standard deviation (RSD) and enhancement factor (EF) were found to be ≤4.8% and 100 respectively. We hope that this method can be introduced for quantitative determination of Cu(II) as a fast, simple, portable, inexpensive, effective, and precise procedure.

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