ChemInform Abstract: VOAFRINE A AND VOAFRINE B, NEW DIMERIC INDOLE ALKALOIDS FROM CELL SUSPENSION CULTURES OF VOACANGA AFRICANA STAPF

1984 ◽  
Vol 15 (11) ◽  
Author(s):  
J. STOECKIGT ◽  
K.-H. PAWELKA ◽  
T. TANAHASHI ◽  
B. DANIELI ◽  
W. E. HULL
Keyword(s):  
Cell Suspension ◽  
Indole Alkaloids ◽  
Cell Suspension Cultures ◽  
Suspension Cultures

Major Indole Alkaloids Produced in Cell Suspension Cultures of Rhazya strict a Decaisne

1986 ◽  
Vol 41 (4) ◽  
pp. 385-390 ◽  
Author(s):  
Karl-Heinz Pawelka ◽  
Joachim Stöckigt
Keyword(s):  
Cell Suspension ◽  
Indole Alkaloids ◽  
Cell Suspension Cultures ◽  
Structural Heterogeneity ◽  
Suspension Cultures ◽  
Cell Suspensions ◽  
Minor Components ◽  
Rhazya Stricta ◽  
First Time

Eleven main alkaloids were identified from cell suspension cultures of Rhazya stricta grown in 4X-medium for 15 days. The alkaloids comprised the five groups Corynanthe, Strychnos, Eburnan, Secodine, and Aspidosperma and can be regarded as being typical Rhazya alkaloids, although the Strychnos alkaloid akuammicine has been isolated for the first time from the genus Rhazya. The most abundant compound was ( + )-1,2-dehydroaspidospermidine (15 mg/l medium) whereas all other constituents were synthesized in about 5 - 10 times lower amounts. More than 15 further alkaloids were formed as minor components which have not yet been identified. Cultivated Rhazya cells have been shown to be one of the richest alkaloid sources from apocynaceous cell suspensions. The isolated compounds, because of their structural heterogeneity, cannot be presently arranged into a scheme with coherent biosynthetic sequences.

Indole Alkaloids from Cell Suspension Cultures of Stemmadenia tomentosa and Voacanga africana

1982 ◽  
Vol 37 (10) ◽  
pp. 857-860 ◽  
Author(s):  
Joachim Stöckigt ◽  
Karl-Heinz Pawelka ◽  
Ana Rother ◽  
Brigitte Deus
Keyword(s):  
Cell Culture ◽  
Cell Suspension ◽  
Growth Condition ◽  
Indole Alkaloids ◽  
Normal Growth ◽  
Cell Suspension Cultures ◽  
Suspension Cultures ◽  
Normal Growth Condition ◽  
Different Types

Abstract Cell suspension cultures of Stemmadenia tomentosa synthesized under normal growth condition the eight major indole alkaloids: (-)-tabersonine, (-)-minovincinine, (+)-conoflorine (voaphyl-line), condylocarpine, (+)-tubotaiwine (dihydrocondylocarpine), (-)-norfluorocurarine (vin-canine), (-)-vinervine, and (-)-coronaridine. These alkaloids consist of the three different types, Aspidosperma, Strychnos and Iboga. In contrast, cultures o f Voacanga africana produced mainly one alkaloid group (Aspidosperma-type) represented by (-)-tabersonine, lochnericine and (-)-minovincinine. Therefore this cell culture seems to be qualified for investigation concerning the biosynthesis of Aspidosperma alkaloids.

Voafrine A and Voafrine B, New Dimeric Indole Alkaloids from Cell Suspension Cultures ofVoacanga africanaStapf

1983 ◽  
Vol 66 (8) ◽  
pp. 2525-2533 ◽  
Author(s):  
Joachim Stöckigt ◽  
Karl-Heinz Pawelka ◽  
Takao Tanahashi ◽  
Bruno Danieli ◽  
William E. Hull
Keyword(s):  
Cell Suspension ◽  
Indole Alkaloids ◽  
Cell Suspension Cultures ◽  
Suspension Cultures

Indole Alkaloids from Ochrosia elliptica Plant Cell Suspension Cultures

1986 ◽  
Vol 41 (4) ◽  
pp. 381-384 ◽  
Author(s):  
Karl-Heinz Pawelka ◽  
Joachim Stöckigt
Keyword(s):  
Cell Suspension ◽  
Natural Product ◽  
Plant Cell ◽  
Indole Alkaloids ◽  
Cell Suspension Cultures ◽  
Suspension Cultures ◽  
Monoterpenoid Indole Alkaloids ◽  
Plant Cell Suspension Cultures ◽  
Plant Cell Suspension

From cell suspension cultures of Ochrosia elliptica Labill. eight different monoterpenoid indole alkaloids were isolated and comprised three alkaloid classes viz. Corynanthe/Heteroyohimbine (tetrahydroalstonine, cathenamine, pleiocarpamine and two methoxylated heteroyohimbines), Strychnos (norfluorocurarine), Apparicine (apparicine and epchrosine). A ll these compounds except the Strychnos alkaloid are biogenetically closely related to the known alkaloids occurring in Ochrosia plants, although such alkaloids have not previously been detected in O. elliptica. Epchrosine has not before been described as a natural product.

The relationship between the accumulation of a 28 kd polypeptide and that of indole alkaloids in Catharanthus roseus cell suspension cultures

1997 ◽  
Vol 150 (4) ◽  
pp. 452-457 ◽  
Author(s):  
Sabine Carpin ◽  
Lazhar Ouelhazi ◽  
Mohamed Filali ◽  
Jean-Claude Chénieux ◽  
Marc Rideau ◽  
...  
Keyword(s):  
Cell Suspension ◽  
Catharanthus Roseus ◽  
Indole Alkaloids ◽  
Cell Suspension Cultures ◽  
Suspension Cultures ◽  
The Relationship
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