Starch nanoparticles as Pickering emulsifiers in miniemulsion polymerization of styrene

2021 ◽  
Author(s):  
Joe Glasing ◽  
Jaime C. Cazotti ◽  
Alexander T. Fritz ◽  
Lilian S. Szych ◽  
Djalal Fakim ◽  
...  
Keyword(s):  
Miniemulsion Polymerization ◽  
Starch Nanoparticles

Mannose Conjugated Starch Nanoparticles for Preferential Targeting of Liver Cancer

2020 ◽  
Vol 17 ◽  
Author(s):  
Akhlesh Kumar Jain ◽  
Hitesh Sahu ◽  
Keerti Mishra ◽  
Suresh Thareja
Keyword(s):  
Side Effects ◽  
Liver Cancer ◽  
Entrapment Efficiency ◽  
Xrd Analysis ◽  
In Vitro Cytotoxicity ◽  
Physical Interaction ◽  
Scanning Calorimetry ◽  
Starch Nanoparticles

Aim: To design D-Mannose conjugated 5-Fluorouracil (5-FU) loaded Jackfruit seed starch nanoparticles (JFSSNPs) for site specific delivery. Background: Liver cancer is the third leading cause of death in world and fifth most often diagnosed cancer is the major global threat to public health. Treatment of liver cancer with conventional method bears several side effects, thus to undertake these side effects as a formulation challenge, it is necessary to develop novel target specific drug delivery system for the effective and better localization of drug into the proximity of target with restricting the movement of drug in normal tissues. Objective: To optimize and characterize the developed D-Mannose conjugated 5-Fluorouracil (5-FU) loaded Jackfruit seed starch nanoparticles (JFSSNPs) for effective treatment of liver cancer. Materials and methods: 5-FU loaded JFSSNPs were prepared and optimized formulation had higher encapsulation efficiency were conjugated with D-Mannose. These formulations were characterized for size, morphology, zeta potential, X-Ray Diffraction, and Differential Scanning Calorimetry. Potential of NPs were studied using in vitro cytotoxicity assay, in vivo kinetic studies and bio-distribution studies. Result and discussion: 5-Fluorouracil loaded NPs had particle size between 336 to 802nm with drug entrapment efficiency was between 64.2 to 82.3%. In XRD analysis, 5-FU peak was diminished in the diffractogram, which could be attributed to the successful incorporation of drug in amorphous form. DSC study suggests there was no physical interaction between 5- FU and Polymer. NPs showed sustained in vitro 5-FU release up to 2 hours. In vivo, mannose conjugated NPs prolonged the plasma level of 5-FU and assist selective accumulation of 5-FU in the liver (vs other organs spleen, kidney, lungs and heart) compared to unconjugated one and plain drug. Conclusion: In vivo, bio-distribution and plasma profile studies resulted in significantly higher concentration of 5- Fluorouracil liver suggesting that these carriers are efficient, viable, and targeted carrier of 5-FU treatment of liver cancer.

Physicochemical properties of starch nanocomposite films enhanced by self-assembled potato starch nanoparticles

LWT ◽  
2016 ◽  
Vol 69 ◽  
pp. 251-257 ◽  
Author(s):  
Suisui Jiang ◽  
Chengzhen Liu ◽  
Xiaojin Wang ◽  
Liu Xiong ◽  
Qingjie Sun
Keyword(s):  
Physicochemical Properties ◽  
Potato Starch ◽  
Nanocomposite Films ◽  
Starch Nanoparticles ◽  
Self Assembled

Combined effect of cassava starch nanoparticles and protein isolate in properties of starch‐based nanocomposite films

2021 ◽  
Vol 138 (18) ◽  
pp. 50008
Author(s):  
Fabiane Cerqueira Almeida ◽  
Carolina Oliveira Souza ◽  
Biane Oliveira Philadelpho ◽  
Paulo Vitor Lemos ◽  
Lucas Guimarães Cardoso ◽  
...  
Keyword(s):  
Cassava Starch ◽  
Protein Isolate ◽  
Combined Effect ◽  
Nanocomposite Films ◽  
Starch Nanoparticles

Influence of esterification and ultrasound treatment on formation and properties of starch nanoparticles and their impact as a filler on chitosan based films characteristics

2021 ◽  
Vol 179 ◽  
pp. 154-160
Author(s):  
Xiaoxia Yan ◽  
Mengxue Diao ◽  
Yali Yu ◽  
Feng Gao ◽  
Erlei Wang ◽  
...  
Keyword(s):  
Ultrasound Treatment ◽  
Starch Nanoparticles

Synthesis of poly(ethylene-co-butylene)-block-poly(ethylene oxide) surfactant and its use in the synthesis of polyhydroxyethyl methacrylate nanoparticles containing azo-dye

RSC Advances ◽  
2014 ◽  
Vol 4 (66) ◽  
pp. 35027-35034 ◽  
Author(s):  
Yee Song Ko ◽  
Monica V. Circu ◽  
Thomas Geiger ◽  
Simon Dünki ◽  
Frank A. Nüesch ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Azo Dye ◽  
Miniemulsion Polymerization ◽  
Hydroxyethyl Methacrylate ◽  
Polyhydroxyethyl Methacrylate ◽  
Inverse Miniemulsion ◽  
Poly Ethylene Oxide ◽  
Disperse Red 1 ◽  
Poly Ethylene

A new poly(ethylene-co-butylene)-block-poly(ethylene oxide) surfactant was synthesized and used in inverse miniemulsion polymerization of 2-hydroxyethyl methacrylate with encapsulated Disperse Red 1.

The Kinetics of Methyl Methacrylate Miniemulsion Polymerization Characterized through a Fluorescence Method

2012 ◽  
Vol 178-181 ◽  
pp. 609-612
Author(s):  
Hai Ke Feng ◽  
Hua Yu Qiu ◽  
Li Yuan Ding ◽  
Cun Jin Xu
Keyword(s):  
Methyl Methacrylate ◽  
Anionic Surfactant ◽  
Sodium Dodecyl Sulphate ◽  
Sodium Dodecyl ◽  
Miniemulsion Polymerization ◽  
Time Measurement ◽  
Fluorescence Method ◽  
Real Time Measurement ◽  
Measurement Results ◽  
Kinetics Of

In this paper, we followed the kinetics of methyl methacrylate (MMA) through a novel fluorescence method. The real-time measurement results show that in the regime of very low monomer contents, such as a solution containing 0.1 wt% of MMA with respect to water and with the anionic surfactant of sodium dodecyl sulphate (SDS), the kinetic of the miniemulsion could be followed by this embed fluorescence method. The processes of changing from emulsion to miniemulsion with different amount of surfactant and cosurfactant also have been monitored.

Particle nucleation and growth in seeded semibatch miniemulsion polymerization of hybrid CeO2/acrylic latexes

Polymer ◽  
2014 ◽  
Vol 55 (3) ◽  
pp. 752-761 ◽  
Author(s):  
Miren Aguirre ◽  
Maria Paulis ◽  
Jose Ramon Leiza
Keyword(s):  
Miniemulsion Polymerization ◽  
Nucleation And Growth ◽  
Particle Nucleation ◽  
Acrylic Latexes

Preparation of Monodisperse Polystyrene Particles from Emulsifier-free Miniemulsion Polymerization

2008 ◽  
Vol 37 (11) ◽  
pp. 1158-1159 ◽  
Author(s):  
Hua Wang ◽  
Sen Zhang ◽  
Mozhen Wang ◽  
Xuewu Ge
Keyword(s):  
Miniemulsion Polymerization ◽  
Monodisperse Polystyrene

Miniemulsion Polymerization Based on Low Energy Emulsification with Preservation of Initial Droplet Identity

2010 ◽  
Vol 43 (19) ◽  
pp. 7905-7907 ◽  
Author(s):  
Siqing Cheng ◽  
Yi Guo ◽  
Per B. Zetterlund
Keyword(s):  
Miniemulsion Polymerization ◽  
Low Energy ◽  
Initial Droplet

Preparation of fluoroacrylate nanocopolymer by miniemulsion polymerization used in textile finishing

2004 ◽  
Vol 94 (4) ◽  
pp. 1466-1472 ◽  
Author(s):  
Pei-Yuan Huang ◽  
Yu-Chou Chao ◽  
Yih-Tyan Liao
Keyword(s):  
Miniemulsion Polymerization ◽  
Textile Finishing
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