Serum levels of vitamin D, PTH and calcium and breast cancer risk-a prospective nested case-control study

2010 ◽  
Vol 127 (9) ◽  
pp. 2159-2168 ◽  
Author(s):  
Martin Almquist ◽  
Anne-Greth Bondeson ◽  
Lennart Bondeson ◽  
Johan Malm ◽  
Jonas Manjer
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

Circulating levels of perfluoroalkylated compounds and breast cancer risk: Evidence from a nested case-control study

2018 ◽  
Vol 66 ◽  
pp. S245
Author(s):  
F.R. Mancini ◽  
G. Cano-Sancho ◽  
J. Gabaretti ◽  
P. Marchand ◽  
J.-P. Antignac ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Nested Case Control ◽  
Circulating Levels ◽  
Control Study

scholarly journals Circulating carotenoids and breast cancer among high-risk individuals

2020 ◽  
Author(s):  
Cheng Peng ◽  
Chi Gao ◽  
Donghao Lu ◽  
Bernard A Rosner ◽  
Oana Zeleznik ◽  
...  
Keyword(s):  
Breast Cancer ◽  
High Risk ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Genetic Risk ◽  
Case Control Study ◽  
Case Control ◽  
Polygenic Risk Score ◽  
Nested Case Control ◽  
Control Study

ABSTRACT Background Carotenoids represent 1 of few modifiable factors to reduce breast cancer risk. Elucidation of interactions between circulating carotenoids and genetic predispositions or mammographic density (MD) may help inform more effective primary preventive strategies in high-risk populations. Objectives We tested whether women at high risk for breast cancer due to genetic predispositions or high MD would experience meaningful and greater risk reduction from higher circulating levels of carotenoids in a nested case-control study in the Nurses’ Health Studies (NHS and NHSII). Methods This study included 1919 cases and 1695 controls in a nested case-control study in the NHS and NHSII. We assessed both multiplicative and additive interactions. RR reductions and 95% CIs were calculated using unconditional logistic regressions, adjusting for matching factors and breast cancer risk factors. Absolute risk reductions (ARR) were calculated based on Surveillance, Epidemiology, and End Results incidence rates. Results We showed that compared with women at low genetic risk or low MD, those with higher genetic risk scores or high MD had greater ARRs for breast cancer as circulating carotenoid levels increase (additive P-interaction = 0.05). Among women with a high polygenic risk score, those in the highest quartile of circulating carotenoids had a significant ARR (28.6%; 95% CI, 14.8–42.1%) compared to those in the lowest quartile of carotenoids. For women with a high percentage MD (≥50%), circulating carotenoids were associated with a 37.1% ARR (95% CI, 21.7–52.1%) when comparing the highest to the lowest quartiles of circulating carotenoids. Conclusions The inverse associations between circulating carotenoids and breast cancer risk appeared to be more pronounced in high-risk women, as defined by germline genetic makeup or MD.

scholarly journals Plasma concentration of brominated flame retardants and postmenopausal breast cancer risk: a nested case-control study in the French E3N cohort

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Francesca Romana Mancini ◽  
German Cano-Sancho ◽  
Oceane Mohamed ◽  
Iris Cervenka ◽  
Hanane Omichessan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Plasma Concentration ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Flame Retardants ◽  
Case Control Study ◽  
Postmenopausal Breast Cancer ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

scholarly journals The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort

2011 ◽  
Vol 13 (2) ◽  
Author(s):  
Eunjung Lee ◽  
Fredrick Schumacher ◽  
Juan Pablo Lewinger ◽  
Susan L Neuhausen ◽  
Hoda Anton-Culver ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Study Cohort ◽  
Hormone Metabolism ◽  
Metabolism Pathway ◽  
Nested Case Control ◽  
Control Study

scholarly journals Vitamin D intake and breast cancer risk: a case–control study in Italy

2009 ◽  
Vol 20 (2) ◽  
pp. 374-378 ◽  
Author(s):  
M. Rossi ◽  
J.K. McLaughlin ◽  
P. Lagiou ◽  
C. Bosetti ◽  
R. Talamini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Vitamin D Intake ◽  
Control Study

scholarly journals Serum enterolactone concentration is not associated with breast cancer risk in a nested case-control study

2003 ◽  
Vol 108 (2) ◽  
pp. 277-280 ◽  
Author(s):  
Annamari Kilkkinen ◽  
Jarmo Virtamo ◽  
Erkki Vartiainen ◽  
Risto Sankila ◽  
Mikko J. Virtanen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

scholarly journals Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0141562 ◽  
Author(s):  
Muhammad Usman Rashid ◽  
Merium Muzaffar ◽  
Faiz Ali Khan ◽  
Maria Kabisch ◽  
Noor Muhammad ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Vitamin D Receptor ◽  
Case Control Study ◽  
Receptor Gene ◽  
Case Control ◽  
Vitamin D Receptor Gene ◽  
Control Study
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