Comparative analysis of the kernel types in generalized autocalibrating partially parallel acquisition algorithms for accelerated three‐dimensional magnetic resonance spectroscopic imaging data

Author(s):  
Junghyun Song ◽  
Dongchan Kim ◽  
Yeji Han ◽  
Jun‐Young Chung
2011 ◽  
Vol 21 (2) ◽  
pp. 69 ◽  
Author(s):  
Edward E Graves ◽  
Andrea Pirzkall ◽  
Tracy R Mcknight ◽  
Daniel B Vigneron ◽  
David A Larson ◽  
...  

Advances in radiation therapy for malignant neoplasms have produced techniques such as Gamma Knife radiosurgery, capable of delivering an ablative dose to a specific, irregular volume of tissue. However, efficient use of these techniques requires the identification of a target volume that will produce the best therapeutic response while sparing surrounding normal brain tissue. Accomplishing this task using conventional computed tomography (CT) and contrast-enhanced magnetic resonance imaging (MRI) techniques has proven difficult because of the difficulties in identifying the effective tumor margin. Magnetic resonance spectroscopic imaging (MRSI) has been shown to offer a clinically-feasible metabolic assessment of the presence and extent of neoplasm that can complement conventional anatomic imaging. This paper reviews current Gamma Knife protocols and MRSI acquisition, reconstruction, and interpretation techniques, and discusses the motivation for including magnetic resonance spectroscopy findings while planning focal radiation therapies. A treatment selection and planning strategy incorporating MRSI is then proposed, which can be used in the future to assess the efficacy of spectroscopy-based therapy planning.


2001 ◽  
Vol 19 (1) ◽  
pp. 89-101 ◽  
Author(s):  
Daniel Vigneron ◽  
Andrew Bollen ◽  
Michael McDermott ◽  
Lawrence Wald ◽  
Mark Day ◽  
...  

1994 ◽  
Vol 14 (3) ◽  
pp. 373-382 ◽  
Author(s):  
Toshihiko Ebisu ◽  
William D. Rooney ◽  
Steven H. Graham ◽  
Michael W. Weiner ◽  
Andrew A. Maudsley

N-acetylaspartate (NAA) has been proposed as a marker of neuronal density. Therefore, regional measurement of NAA by magnetic resonance spectroscopic imaging (MRSI) may provide a sensitive method for detection of selective neuronal loss, in contrast to conventional imaging techniques such as magnetic resonance imaging (MRI). To test this hypothesis, we produced selective neuronal injury by kainate-induced status epilepticus. Three days later three-dimensional 1H-MRSI was obtained and compared with conventional T2-weighted MRI and histological findings in normal and kainatetreated rats. Reduction of NAA determined by MRSI in piriform cortex, amygdala, and hippocampus correlated well with neuronal injury determined from histology. Changes of NAA, without any MRI changes in hippocampus, indicated greater sensitivity of MRSI for detection of neuronal injury. These results are consistent with the hypothesis that reduction of NAA measured by MRSI may be a sensitive marker of neuronal injury in vivo in a variety of disease states.


2007 ◽  
Vol 58 (5) ◽  
pp. 886-892 ◽  
Author(s):  
Yan Li ◽  
Albert P. Chen ◽  
Jason C. Crane ◽  
Susan M. Chang ◽  
Daniel B. Vigneron ◽  
...  

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