scholarly journals A panel of three serum microRNA can be used as potential diagnostic biomarkers for nasopharyngeal carcinoma

2022 ◽  
Author(s):  
Rongkang Li ◽  
Chong Lu ◽  
Weiqiang Yang ◽  
Yaqi Zhou ◽  
Jiatao Zhong ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Diagnostic Biomarkers ◽  
Serum Microrna

scholarly journals Serum microRNA expression profiling revealing potential diagnostic biomarkers for lung adenocarcinoma

2020 ◽  
Vol 133 (21) ◽  
pp. 2532-2542
Author(s):  
Xia Shan ◽  
Lan Zhang ◽  
Dan-Xia Zhu ◽  
Xin Zhou ◽  
Huo Zhang ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Expression Profiling ◽  
Microrna Expression ◽  
Diagnostic Biomarkers ◽  
Serum Microrna

Conventional and Novel Diagnostic Biomarkers and Approaches for Detection of Nasopharyngeal Carcinoma

2019 ◽  
pp. 129-153
Author(s):  
Honglin Chen ◽  
Mingfang Ji ◽  
Jing Feng Zong ◽  
Josephine Mun-Yee Ko ◽  
Wei Dai ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Diagnostic Biomarkers

Serum microRNA profiles as diagnostic biomarkers for HBV-positive hepatocellular carcinoma

2017 ◽  
Vol 37 (6) ◽  
pp. 888-896 ◽  
Author(s):  
Hao-Tu Zhu ◽  
Rong-Bin Liu ◽  
Ya-Yong Liang ◽  
Abdulbaqi M. E. Hasan ◽  
Hai-Yun Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Diagnostic Biomarkers ◽  
Serum Microrna

scholarly journals Serum proteomic-based analysis identifying autoantibodies against PRDX2 and PRDX3 as potential diagnostic biomarkers in nasopharyngeal carcinoma

2017 ◽  
Vol 14 (1) ◽  
Author(s):  
Lie-Hao Lin ◽  
Yi-Wei Xu ◽  
Li-Sheng Huang ◽  
Chao-Qun Hong ◽  
Tian-Tian Zhai ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Diagnostic Biomarkers

scholarly journals Differential Expression of miR-101 and miR-744 in Nasopharyngeal Carcinoma in Pahang State of Malaysia

2018 ◽  
Vol 16 (5) ◽  
pp. 295-306
Author(s):  
Azmir AHMAD ◽  
Haziq Abdul WAHID ◽  
Wan Ishlah LEMAN ◽  
Noor Syamila OTHMAN ◽  
Azlina Abdul RAHMAN ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Sample Size ◽  
Differential Expression ◽  
Control Group ◽  
Roc Curve Analysis ◽  
Diagnostic Biomarkers ◽  
Total Rna ◽  
Formalin Fixed Paraffin ◽  
Ffpe Samples ◽  
Formalin Fixed Paraffin Embedded

Previous study found that microRNA-101 (miR-101) and microRNA-744 (miR-744) were deregulated in head and neck cancers and were implicated in nasopharyngeal carcinoma (NPC) carcinogenesis. Thus, this study aimed to determine the expression of miR-101 and miR-744 in NPC and analyse the utility of these microRNAs (miRNAs) as diagnostic biomarkers. Total RNA was extracted from 31 NPC and 7 non-NPC control formalin-fixed paraffin-embedded (FFPE) samples. Complementary DNA (cDNA) was synthesized from the total RNA and proceeded with quantitative real-time polymerase chain reaction. Differential expression of miR-101 and miR-744 were calculated from quantification cycle (Cq) data using 2-ΔΔCq calculation. The performance of these miRNAs were calculated using receiver operating characteristic (ROC) curve analysis. The differential expression for miR-101 and miR-744 were -1.39 (p < 0.05) and 2.48 (p > 0.05), respectively, where the deregulations were consistent with the previous report. The area under curve for miR-101, miR-744 and combination of miR-101 and miR-744 were 0.654 (95 % CI: 0.465 - 0.844), 0.588 (95 % CI: 0.368 - 0.808) and 0.626 (95 % CI: 0.481 - 0.771), respectively. However, re-analysis using balanced sample size between NPC and non-NPC control group showed the value decreased to 0.653 (95 % CI: 0.347 - 0.959) for miR-101 but increased to 0.827 (95 % CI: 0.601 - 1.000) for miR-744 and 0.758 (95 % CI: 0.576 - 0.939) for the combination of miR-101 and miR-744, indicating the importance of having a balanced sample size. We have successfully determined the expression of miR-101 and miR-744 in NPC samples. We also demonstrated statistically the utility of these miRNAs as diagnostic biomarkers.

scholarly journals miRNAs derived from circulating small extracellular vesicles as diagnostic biomarkers for nasopharyngeal carcinoma

2021 ◽  
Author(s):  
Li Jiang ◽  
Yong Zhang ◽  
Bo Li ◽  
Min Kang ◽  
Zhendong Yang ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Extracellular Vesicles ◽  
Diagnostic Biomarkers

An Established Epithelial Cell Line (NPC/HK1) from a Nasopharyngeal Carcinoma - II. A Sem Study

1982 ◽  
Vol 40 ◽  
pp. 224-225
Author(s):  
Li C.L. ◽  
Chew E.C. ◽  
Huang D.P. ◽  
Ho H.C. ◽  
Mak L.S. ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Epithelial Cell ◽  
Surface Morphology ◽  
Cell Line ◽  
Epithelial Cell Line ◽  
Present Communication ◽  
Cells In Culture ◽  
Sem Study ◽  
Well Differentiated

An epithelial cell line, NPC/HK1, has recently been successfully established from a nasopharyngeal carcinoma of the moderately to well differentiated squamous type. The present communication reports on the surface morphology of the NPC/HK1 cells in culture.

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