Enhanced production of lovastatin in a bubble column byAspergillus terreus using a two-stage feeding strategy

2006 ◽  
Vol 82 (1) ◽  
pp. 58-64 ◽  
Author(s):  
EM Rodríguez Porcel ◽  
JL Casas López ◽  
JA Sánchez Pérez ◽  
Y Chisti
2014 ◽  
Vol 152 ◽  
pp. 162-168 ◽  
Author(s):  
Yi-Xiang Zhu ◽  
Ling-Yun Yao ◽  
Rui-Hua Jiao ◽  
Yan-Hua Lu ◽  
Ren-Xiang Tan

2019 ◽  
Vol 68 (2) ◽  
pp. 561-566 ◽  
Author(s):  
Sheng-Jie Yue ◽  
Peng Huang ◽  
Song Li ◽  
Malik Jan ◽  
Hong-Bo Hu ◽  
...  

RSC Advances ◽  
2019 ◽  
Vol 9 (45) ◽  
pp. 26532-26536 ◽  
Author(s):  
Yifeng Yang ◽  
Yilin Hou ◽  
Zhaohui Chen ◽  
Huiqiu Wang ◽  
Yu Wang ◽  
...  

High-yield production of aromatics from propane with a temperature shifting, two-stage fluidized bed reactor technology.


2007 ◽  
Vol 292 (5) ◽  
pp. L1233-L1240 ◽  
Author(s):  
Navneet Kaur Dhillon ◽  
David Pinson ◽  
Sukhbir Dhillon ◽  
Ossama Tawfik ◽  
Marsha Danley ◽  
...  

Pneumonia is a major complication of human immunodeficiency virus (HIV) pathogenesis but it develops only after prolonged infection. We used the macaque model to explore a hypothesis that the disease is a two-stage process, the first stage being establishment of the viral infection in the lung and the second being amplification of virus replication by host factors induced by chemical agents or opportunistic pathogens in the lung. Bleomycin, a chemical known to induce diffuse alveolar damage and pulmonary fibrosis with accumulation of macrophages and a rich T helper type 2 (Th2) cytokine environment, was inoculated intratracheally into five of eight SHIV 89.6P-infected macaques and into one uninfected macaque. Three additional simian HIV (SHIV)-infected macaques without bleomycin treatment served as untreated virus controls. Although none of the animals became clinically ill, bleomycin induced classical host responses in the lungs of all the treated, virus-infected macaques. There was enhanced production of the chemokine, monocyte chemotactic protein-1 (MCP-1), that had previously been shown to cause enhanced replication of the virus. Four of the five treated animals developed more productive SHIV infection in the lungs compared with the infected untreated animals. Enhanced virus replication was found primarily in infiltrating macrophages. Enhanced replication of the virus in the lungs was associated with host factors induced by the drug and supported the hypothesis for a two-stage process of pulmonary pathogenesis.


Author(s):  
Hafiz M. Abd-ur-Rehman ◽  
Fahad A. Al-Sulaiman ◽  
Mohamed A. Antar

The fresh water is the essence of life and its scarcity is the most threatening concern for mankind. To alleviate the worries of the existing and approaching fresh water crisis, the answer for water sustainability may lie in developing the decentralized small-scale water desalination system. Solar humidification-dehumidification (HDH) is a carrier gas based thermal technique that is ideal for a small-scale decentralized water desalination system. An innovative design approach is to use the bubble column humidifier to enhance the performance of the HDH water desalination system. Therefore, a novel multi-stage stepped bubble column humidifier is proposed that is operated through solar thermal energy as the main source of energy input. The study addresses the relation between the pressure drop variations with varying water column height at different air superficial velocities. Findings revealed that the water column height and air superficial velocity should be optimized according to the geometric features of the perforated plate in order to achieve a higher humidifier performance with a lower pressure drop. The day round performance of the humidifier is investigated in single stage, two stage, and three stage configurations. Findings show that the average day round absolute humidity at the exit of the humidifier is increased by 9 % in two-stage and 23 % in three-stage configurations compared to the single stage humidifier. One major advantages of this proposed humidifier is its ability to have a direct solar thermal heating. Subsequently, it can be located in remote areas.


2014 ◽  
Vol 159 ◽  
pp. 112-117 ◽  
Author(s):  
Ling-Yun Yao ◽  
Yi-Xiang Zhu ◽  
Rui-Hua Jiao ◽  
Yan-Hua Lu ◽  
Ren-Xiang Tan

2012 ◽  
Vol 97 (2) ◽  
pp. 573-583 ◽  
Author(s):  
Shuwen Liu ◽  
Yong Liang ◽  
Qian Liu ◽  
Tongtong Tao ◽  
Shujuan Lai ◽  
...  

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