Effect of ginkgo biloba on the in vitro labeling of red blood cells and plasma proteins with technetium-99M

2001 ◽  
Vol 44 (S1) ◽  
pp. S639-S641 ◽  
Author(s):  
S. R. F. Moreno ◽  
G. D. Feliciano ◽  
R. S. Freitas ◽  
D. M. Mattos ◽  
M. L. Gomes ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Ginkgo Biloba ◽  
Blood Cells ◽  
Plasma Proteins ◽  
Technetium 99M

Ginkgo biloba Extract: Experimental Model to Evaluate its Action on the Labeling of Blood Elements with Technetium-99m and on the Morphometry of Red Blood Cells

2003 ◽  
Vol 3 (1) ◽  
pp. 68-71 ◽  
Author(s):  
S.R.F. Moreno . ◽  
E.K. Rocha . ◽  
M. Pereira . ◽  
C. Mandarim-Lacerda . ◽  
R.S. Freitas . ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Experimental Model ◽  
Ginkgo Biloba ◽  
Blood Cells ◽  
Ginkgo Biloba Extract ◽  
Technetium 99M ◽  
Blood Elements

5. Effect of caffeine on the labeling of red blood cells and plasma proteins with technetium-99m

1999 ◽  
Vol 20 (10) ◽  
pp. 954-955
Author(s):  
S. R.F. Moreno ◽  
A. P. Motta ◽  
R. C. Cardoso ◽  
G. B.X. Lins ◽  
M. Bernardo-Filho
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Plasma Proteins ◽  
Technetium 99M

Effect of Peumus boldus on the labeling of red blood cells and plasma proteins with Technetium-99m

1999 ◽  
Vol 51 (2) ◽  
pp. 145-149 ◽  
Author(s):  
Ingrid Wancke Reiniger ◽  
Joelma Fonseca de Oliveira ◽  
Adriano Caldeira-de-Araújo ◽  
Mario Bernardo-Filho
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Plasma Proteins ◽  
Technetium 99M

scholarly journals Experimental models using radionuclides for assessment of the effects of natural drugs

2008 ◽  
Vol 51 (spe) ◽  
pp. 169-174 ◽  
Author(s):  
Silvana Ramos Farias Moreno ◽  
Jorge José de Carvalho ◽  
Bernardo Rebello ◽  
Emely Kazan Rocha ◽  
Margareth de Oliveira Timóteo ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Ginkgo Biloba ◽  
Blood Cells ◽  
Experimental Models ◽  
Significant Alteration ◽  
Blood Constituents ◽  
Technetium 99M ◽  
Sodium Pertechnetate ◽  
Natural Drugs

The aim of this study was to evaluate the effect of the extracts of Nectandra membranacea (N. membranacea), Ginkgo biloba (EGb) and Passiflora (PEF) on the morphology of red blood cells (RBC), on the biodistribution of sodium pertechnetate (99mTcO4Na), on the morphology of duodenum and on the labeling of blood constituents (BC, IF-P, IF-BC) with technetium-99m (Tc-99m). Morphometry studies also were performed. The results show that EGb promotes alteration of the labeling of BC, IF-P and IF-BC (p<0.05). The N. membranacea extract does not promote significant alteration of the radiolabeling, and PEF extract alters the IF-P labeling. N. membranacea, EGb and PEF extracts were able to alter the RBC morphology (P<0.05). N. membranacea extract and EGb modifies the biodistribution of the 99mTcO4Na, and EGb influences the morphometry of duodenum isolated from rats (P<0.05).

37. Analysis of eggplant (Solanum melongena) both in vitro and in vivo 99mTc labelling of red blood cells and plasma proteins from Wistar rat

1999 ◽  
Vol 20 (10) ◽  
pp. 965
Author(s):  
P. V.S.Z. Capriles ◽  
A. P.M. Dias ◽  
T. E.M.M. Costa ◽  
E. G. Moura ◽  
J. F. Oliveira ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Plasma Proteins ◽  
Solanum Melongena ◽  
Wistar Rat ◽  
99Mtc Labelling

scholarly journals Effect of a peel passion fruit flour (Passiflora edulis f. flavicarpa) extract on the labeling of blood constituents with technetium-99m and on the morphology of red blood cells

2007 ◽  
Vol 50 (spe) ◽  
pp. 153-159 ◽  
Author(s):  
Bernardo Machado Rebello ◽  
Silvana Ramos Farias Moreno ◽  
Camila Godinho Ribeiro ◽  
Rosane de Figueiredo Neves ◽  
Adenilson de Souza da Fonseca ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Plasma Proteins ◽  
Area Ratio ◽  
Passiflora Edulis ◽  
Blood Constituents ◽  
Technetium 99M ◽  
Morphological Evaluation ◽  
Blood Smears ◽  
Ratio Determination

Passiflora edulis f. flavicarpa (maracuja) is a fruit consumed in Brazil and worldwide. Blood constituents labeled with technetium-99m (99mTc) are used in nuclear medicine. The effect of P. flavicarpa extract on the radiolabeling of blood constituents and on red blood cells morphology was evaluated. Blood samples from Wistar rats was incubated with P. flavicarpa extract. After that, the labeling of blood constituents with 99mTc was carried out. Samples of plasma and blood cells were precipitated with trichloroacetic acid to isolate the soluble and insoluble fractions of plasma and blood cells. The radioactivity in each fractions was counted and the percentage of radioactivity was determined. Blood smears were also prepared to morphological evaluation and perimeter/area ratio determination. P. flavicarpa extract altered (p<0.05) the fixation of 99mTc on plasma proteins and the perimeter/area ratio of red blood cells. Substances present in P. flavicarpa extract could affect the labeling of blood constituents with 99mTc acting in specific targets as membrane of red blood cells.

Assessment of the effect of Maytenus ilicifolia (espinheira santa) extract on the labeling of red blood cells and plasma proteins with technetium-99m

2000 ◽  
Vol 72 (1-2) ◽  
pp. 179-184 ◽  
Author(s):  
Joelma Fonseca de Oliveira ◽  
Ana Cristina S Braga ◽  
Márcia B Nunes de Oliveira ◽  
Antonio Sérgio Ávila ◽  
Adriano Caldeira-de-Araújo ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Plasma Proteins ◽  
Technetium 99M ◽  
Maytenus Ilicifolia

scholarly journals Effect of an extract of Artemisia vulgaris L. (Mugwort) on the in vitro labeling of red blood cells and plasma proteins with technetium-99m

2007 ◽  
Vol 50 (spe) ◽  
pp. 123-128 ◽  
Author(s):  
Danielle Amorim Terra ◽  
Lúcia de Fátima Amorim ◽  
Maria Tereza Jansen de Almeida Catanho ◽  
Adenilson de Souza da Fonseca ◽  
Sebastião David Santos-Filho ◽  
...  
Keyword(s):  
Blood Cells ◽  
Plasma Proteins ◽  
Trichloroacetic Acid ◽  
Wistar Rats ◽  
Insoluble Fraction ◽  
Artemisia Vulgaris ◽  
Blood Samples ◽  
Blood Constituents ◽  
Technetium 99M

The aim of this work was to evaluate the effect of an extract of the Artemisia vulgaris L. (mugwort) on the labeling of blood constituents with technetium-99m (99mTc). Blood samples from Wistar rats were incubated with a mugwort extract and the radiolabeling of blood constituents was carried out. Plasma and blood cells were separated by centrifugation. Aliquots of plasma and blood cells were also precipitated with trichloroacetic acid and centrifuged to isolate soluble and insoluble fractions of plasma and blood cells. Radioactivity in each fraction was counted and the percentages of radioactivity (%ATI) was calculated. Mugwort extract decreased significantly (p<0.05) the %ATI on the blood compartments and on the blood cells proteins (insoluble fraction). The analysis of the results indicates that the extract could have substances that could interfere on the transport of stannous through the erythrocyte membrane alterating the labeling of blood cells with 99mTc.

scholarly journals An extract of a formula used in the traditional chinese medicine (Buzhong Yi Qi Wan) alters the labeling of blood constituents with technetium-99m

2007 ◽  
Vol 50 (spe) ◽  
pp. 111-116 ◽  
Author(s):  
Tania Santos Giani ◽  
Severo de Paoli ◽  
Giuseppe Antonio Presta ◽  
Adalgisa Ieda Maiworm ◽  
Sebastião David Santos-Filho ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Blood Cells ◽  
Plasma Proteins ◽  
Cellular Membrane ◽  
Blood Constituents ◽  
Technetium 99M ◽  
99Mtc Labeling ◽  
Blood Cell And Plasma

Buzhong Yi Qi Wan (Buzhong) is a medicinal herb widely used in Traditional Chinese Medicine to treat the digestive and circulatory systems. Red blood cell and plasma proteins labeled with technetium-99m (99mTc) are used in nuclear medicine. The aim of this work was to investigate the effects of an aqueous Buzhong extract on the labeling of blood constituents with 99mTc. Heparinized blood (Wistar rats) was incubated in vitro with different Buzhong extract concentrations and 99mTc-labeling was performed. Plasma (P) and blood cells (BC) were separated and soluble (SF-P, SF-BC) and insoluble (IF-P, IF-BC) fractions were isolated. The radioactivity on blood constituents was determined and the percentage of incorporated radioactivity (%ATI) was calculated. Buzhong extract at the highest concentrations used altered significantly (p<0.05) the %ATI in blood constituents. Substances present in the Buzhong extract could alter the cellular membrane and/or generation of free radicals that have oxidant properties modifying the labeling of blood constituents with 99mTc.

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