scholarly journals Clinical status, biochemical profile and management of a single cohort of patients with arginase deficiency

JIMD Reports ◽  
2021 ◽  
Author(s):  
Nandaki Keshavan ◽  
Michelle Wood ◽  
Lucy M. Alderson ◽  
Mario Cortina‐Borja ◽  
Rachel Skeath ◽  
...  
Keyword(s):  
Clinical Status ◽  
Biochemical Profile ◽  
Arginase Deficiency ◽  
Single Cohort

scholarly journals Follow up of Patients with Parathyroid Adenoma Detected by Parathyroid Scan

2018 ◽  
Vol 20 (2) ◽  
pp. 119
Author(s):  
Shahnaz Begum ◽  
Fatima Begum ◽  
Shamima Yeasmin ◽  
Tania Sultana ◽  
Afroza Begum ◽  
...  
Keyword(s):  
Operative Treatment ◽  
Clinical Status ◽  
Mean Value ◽  
Biochemical Profile ◽  
Sestamibi Scan ◽  
Male Patients ◽  
The Mean ◽  
One Year ◽  
The One

<p><strong><em>Background:</em></strong> Primary hyperparathyroidism (PHPT) is the third most endocrine disorder after diabetes and thyroid disease. The objective of this study was to observe the outcome of those patients who had positive parathyroid scan with Technetium-99m (<sup>99m</sup>Tc) sestamibi scan  referred to National Institute of Nuclear Medicine &amp; Allied Sciences (NINMAS) to perform parathyroid scan.<strong></strong></p><p><strong><em>Patients and Methods</em></strong><em>:</em> This longitudinal observational type of study was carried out at NINMAS, from January 2016 to December 2016. A total number of 43 hyperparathyroid patients who had positive parathyroid scan were included in this study during one year follow up period. There clinical status, biochemical profile &amp; treatment history were evaluated Chi-quire and paired t-test were used to analyze the variables.</p><p><strong><em>Results:</em></strong><strong> </strong>Among 43 study patients, number of male patients was 26 (60.5%) and female patients were 17 (39.5%). The mean ± SD age was 42.44 ± 12.11 years and majority was in age group 41-50 years<strong>. </strong>It was observed that 40 (93.0%) patients were symptomatic and only 3 (7.0%) were asymptomatic. Regarding symptoms, majority (81.4%) patients had bone pain followed by renal stone (58.1%). More than half (55.8%) patient had abdominal pain or cramps. Twenty nine (67.4.0%) patients undergone operation and 14 (32.6%) patients did not receive operative treatment at the one year follow up period.  Among 43 patients 29 (67.4%) were operated and all operated patients relieved their symptoms whereas patients 14 (32.6%) had not undergone operation and their symptoms persisted. There was strong statistical significant association (P&lt;0.05) between operation and relief of symptoms. The biochemical profile of study patients showed that preoperative mean serum calcium level was 10.92±2.85 mg/dl which reduced after operation (7.53±2.75 mg/dl). The mean value of serum parathyroid hormone (PTH) level also reduced from 748±744.77 pg/ml to 171.61±168.23 pg/ml.</p><p><strong><em>Conclusion:</em></strong> Among all patients, 67.4% received operative treatment and were relieved from symptoms at one year follow up. Significant number of hyperparathyroid patients (32.6%) failed to receive operative treatment due to poor economic condition. More awareness is needed among physicians and patients about immediate operative treatment to alleviate their sufferings as well as to avoid crippling complications.</p><p>Bangladesh J. Nuclear Med. 20(2): 119-123, July 2017</p>

Public Reporting of Cardiovascular Data: Benefits, Pitfalls, and Vision for the Future

2016 ◽  
Vol 10 (1) ◽  
pp. 36
Author(s):  
Gregory J Dehmer ◽  
Keyword(s):  
Clinical Data ◽  
Clinical Status ◽  
Public Reporting ◽  
Professional Organizations ◽  
Healthcare Data ◽  
Outcomes Of Care ◽  
The Future ◽  
Policy Statements ◽  
Quality And Outcomes ◽  
Reporting Programs

Public reporting of healthcare data is not a new concept. This initiative continues to proliferate as consumers and other stakeholders seek information on the quality and outcomes of care. Furthermore, mandates for the development of additional public reporting efforts are included in several new healthcare legislations such as the Affordable Care Act. Many current reporting programs rely heavily on administrative data as a surrogate for true clinical data, but this approach has well-defined limitations. Clinical data are traditionally more difficult and costly to collect, but more accurately reflect the clinical status of the patient, thus enhancing validity of the quality metrics and the reporting program. Several professional organizations have published policy statements articulating the main principles that should establish the foundation for public reporting programs in the future.

Phenotypic classification and biochemical profile of obesity for cardiovascular prevention

2020 ◽  
Vol 179 (5) ◽  
Author(s):  
Marco A. Perrone ◽  
Jagadish Babu Dasari ◽  
Alfredo Intorcia ◽  
Paola Gualtieri ◽  
Massimo Marche ◽  
...  
Keyword(s):  
Cardiovascular Prevention ◽  
Biochemical Profile ◽  
Phenotypic Classification

Effects of X-Ray Exposure on Some CMI Regulatory Cytokines in Technicians Serum Samples

2018 ◽  
Vol 9 (4) ◽  
Author(s):  
Weam S Al-Hamadany
Keyword(s):  
Clinical Status ◽  
Cell Mediated Immunity ◽  
Normal Range ◽  
Serum Samples ◽  
X Ray ◽  
Immunosuppressive Factor ◽  
Elisa Technique ◽  
Immunological Process ◽  
Field Workers ◽  
Tomography Scan

Ionizing radiation considered as an immunosuppressive factor upon over dose of exposure. Radiation field workers usually following a periodic checkup to monitor changes in their clinical status. Cell Mediated Immunity (CMI) has an important cytokines that regulate this specific immunological process. This study estimated the Interleukins (IL-2, IL-12 and IL-18) levels in serum samples using ELISA technique. Serum samples were collected from X-ray Technicians (Radiography, Fluoroscopy and Computed Tomography Scan Technicians) working in AL-Muthanna governorate hospitals. A total of (60) technicians and (30) control were involved in this research. Results showed significant decrease in IL-2 levels and increase in IL-18 levels in test groups (technicians) as compared with controls. While, IL-12 levels did not show a difference; all obtained values were within normal range. Overdose of X-ray exposure caused CMI suppression via disturbing the levels of critical cytokines (IL-2 and IL-18) leading to CMI loss regulation.

Terson sign:

2020 ◽  
Vol 2 (1) ◽  
pp. 38-43
Author(s):  
Luiz Severo Bem Junior ◽  
Gustavo De Souza Andrade ◽  
Joao Ribeiro Memória Júnior ◽  
Hildo Rocha Cirne de Azevedo Filho
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Early Recognition ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Case Reports ◽  
Clinical Status ◽  
Vitreous Hemorrhage ◽  
Anterior Communicating Artery ◽  
Inclusion Criteria ◽  
Relationship Of ◽  
The Relationship

Terson's sign (TS) is classically defined as vitreous hemorrhage associated with subarachnoid hemorrhage of aneurysmal origin, being an important predictor of severity, indicating greater morbidity and mortality when compared to patients without the sign. The objective of this study is to review the relationship of Terson syndrome/Terson sign with the prognosis of aneurysmal subarachnoid hemorrhage. A search for original articles, research and case reports was performed on the PubMed, Scielo, Cochrane and ScienceDirect platform, with the following descriptors: Terson sign and subarachnoid hemorrhage. Retrospective, prospective articles and case reports published in the last 5 years and which were in accordance with the established objective and inclusion criteria were selected. Ten (10) articles were selected, in which the available results show an unfavorable prognostic relationship of TS and subarachnoid hemorrhage, because these patients had a worse clinical status assessed on the Glasgow scales ≤ 8, Hunt & Hess > III, Fisher > 3, in addition to intracranial hypertension and location of the aneurysm in the anterior communicating artery complex. The early recognition of this condition described by Albert Terson in 1900 brought an important contribution to neurosurgery, being recognized until nowadays.

Arthroscopy in Arthrosis: Is It Worth it? A case Presentation

2018 ◽  
Vol 69 (8) ◽  
pp. 2232-2235
Author(s):  
Marius Moga ◽  
Mark Edward Pogarasteanu ◽  
Antoine Edu
Keyword(s):  
Clinical Status ◽  
Loose Body ◽  
Point Of View ◽  
The Other ◽  
Joint Range Of Motion ◽  
Objective Evidence ◽  
Before And After ◽  
Total Knee ◽  
Joint Range

The role of arthroscopy in incipient and mild arthrosis, even combined with proximal tibial ostetomy, is well known and well documented. On the other hand, its role in the treatment of advanced arthrosis of the large joints, especially the knee, is a subject of controversy. The proponents of the use of arthroscopy in advanced arthrosis claim that meniscectomy, synovectomy, ostophytectomy, chondral lesion stabilization, arthroscopic release, plica and loose body removal greatly improve the quality of life for most patients, especially if followed by the use of viscoelastic injection, by diminishing pain and improving joint range of motion. The opponents claim that, even though the advantages are clear in the cases that refuse arthroplasty, in all the other cases the surgical indication should be total knee arthroplasty, as the clinical relief is temporary, but with all the risks of a surgical intervention. We have conducted an overview of the recent literature, in order to find objective evidence to sustain either point of view. We focused on articles published that included an objective measurement of before and after clinical status through clinical scores and objective measurements. We also focused on the follow-up period and on the evolution of the pathology after arthroscopy.

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