Prevalence and genotype distribution of human papillomavirus in non-neoplastic cervical tissue lesion: Cervical erosion

2011 ◽  
Vol 83 (11) ◽  
pp. 1997-2003 ◽  
Author(s):  
Aysen Bayram ◽  
Suna Erkılıç ◽  
Özcan Balat ◽  
Fahriye Ekşi ◽  
Mete Gürol Uğur ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Genotype Distribution ◽  
Cervical Tissue ◽  
Tissue Lesion

scholarly journals Prevalence and genotype distribution of human papillomavirus in Czech non-vaccinated heterosexual couples

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Hana Jaworek ◽  
Vladimira Koudelakova ◽  
Ivana Oborna ◽  
Blazena Zborilova ◽  
Jana Brezinova ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Hpv Infection ◽  
Sexual Partners ◽  
Fisher Exact Test ◽  
Genotype Distribution ◽  
Heterosexual Couples ◽  
Anatomic Site ◽  
Hpv Dna ◽  
Hpv Test ◽  
Penile Swabs

Abstract Background Data about the genotype-specific human papillomavirus (HPV) prevalence in the Czech Republic is limited. We aimed to evaluate the prevalence and concordance of genotype-specific HPV infection detected in semen samples, penile swabs and cervical swabs from non-vaccinated heterosexual couples without HPV-associated disease. Methods Semen samples and penile swabs were collected from male partners and cervical swabs were collected from female partners of heterosexual couples treated for infertility (n = 195). Presence of HPV DNA in semen samples and cervical swabs was analyzed using the cobas® HPV Test and PapilloCheck®. Only the PapilloCheck® test was used to detect HPV in penile swabs. The genotype-specific prevalence and concordance of HPV infection not targeted by vaccine were evaluated using Fisher exact test. Results Both partners were infected with any HPV type in 13.8% (27/195) of couples and, of these couples, 55.6% (15/27) harbored at least one mutual genotype. High-risk HPV (hrHPV) genotypes were detected in 12.3% (24/195) of semen samples, 31.3% (61/195) of penile swabs, and 19.5% (38/195) of cervical swabs (P < 0.001). The most prevalent hrHPV genotype were HPV53 (2.56%; 5/195) in semen samples, HPV16 (6.67%, 13/195) in penile swabs and HPV39 (3.59%, 7/195) in cervical swabs. Low-risk (lrHPV) genotypes were detected in 5.13% (10/195) of semen samples, 15.9% (31/195) of penile swabs, and 4.10% (8/195) of cervical swabs (P < 0.001). Male sexual partners of HPV-positive women were more likely to be infected with at least one of the same HPV types than female sexual partners of HPV-positive men (34.9% vs. 17.9%, P = 0.055). Conclusions This study showed that the detection of HPV infection differ by anatomic site and gender. Regardless the anatomic site, high prevalence of HPV genital infection was found in both Czech men and women.

scholarly journals Human Papillomavirus Prevalence and Genotype Distribution among HIV-Infected Women in Korea

2014 ◽  
Vol 29 (1) ◽  
pp. 32 ◽  
Author(s):  
Eun Kyoung Park ◽  
Heerim Cho ◽  
Sun Hee Lee ◽  
Seung Geun Lee ◽  
Sang Yeup Lee ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Genotype Distribution

Prevalence of human papillomavirus and genotype distribution in women undergoing cervical cancer screening in the area of Barbastro, Spain

2016 ◽  
Vol 49 (4) ◽  
pp. 208-213
Author(s):  
María Dolores Comes ◽  
Rosa Oncíns ◽  
Eduardo Clemente ◽  
María Ángeles Aragón ◽  
Ana Cortés ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Genotype Distribution

scholarly journals Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program

2014 ◽  
Vol 22 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Everton Faccini Augusto ◽  
Larissa Silva dos Santos ◽  
Ledy do Horto dos Santos Oliveira
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
High Risk ◽  
Health Program ◽  
Vaccine Coverage ◽  
Family Health ◽  
Polymorphism Analysis ◽  
Genotype Distribution ◽  
Cross Sectional Survey ◽  
Family Health Program

OBJECTIVES: to survey the prevalence of human papillomavirus, associated risk factors and genotype distribution in women who were referred to cervical cancer screening when attended in a Family Health Program. METHOD: we conducted a cross-sectional survey, investigating 351 women. Polymerase chain reaction for DNA amplification and restriction fragment length polymorphism analysis were used to detect and typify the papillomavirus. RESULTS: virus infection was detected in 8.8% of the samples. Among the 21 different genotypes identified in this study, 14 were high risk for cervical cancer, and the type 16 was the most prevalent type. The infection was associated with women who had non-stable sexual partners. Low risk types were associated with younger women, while the high risk group was linked to altered cytology. CONCLUSION: in this sample attended a Family Health Program, we found a low rate of papillomavirus infection. Virus frequency was associated to sexual behavior. However, the broad range of genotypes detected deserves attention regarding the vaccine coverage, which includes only HPV prevalent types.

scholarly journals Human Papillomavirus Genotype Distribution and E6/E7 Oncogene Expression in Turkish Women with Cervical Cytological Findings

2014 ◽  
Vol 15 (9) ◽  
pp. 3997-4003 ◽  
Author(s):  
Seda Tezcan ◽  
Didem Ozgur ◽  
Mahmut Ulger ◽  
Gonul Aslan ◽  
Iclal Gurses ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Genotype Distribution ◽  
Turkish Women ◽  
Oncogene Expression ◽  
E7 Oncogene

scholarly journals Prevalence and Genotype Distribution of Human Papillomavirus Among a Subpopulation of Jordanian Women

2020 ◽  
Vol 9 (1) ◽  
pp. 017-023
Author(s):  
Ashraf I Khasawneh ◽  
Fida F Asali ◽  
Rami M Kilani ◽  
Jumana A Abu-Raideh ◽  
Nisreen M Himsawi ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Genotype Distribution

scholarly journals Genotype Distribution and Prevalence of Human Papillomavirus in Head and Neck Cancer Samples from Istanbul, Turkey

Pathogens ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1533
Author(s):  
Muammer Osman Köksal ◽  
Başak Keskin Yalçın ◽  
Fahriye Keskin ◽  
Sevgi Çiftçi ◽  
Ibrahim Yağcı ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Head And Neck ◽  
Significant Proportion ◽  
Developed Countries ◽  
Genotype Distribution ◽  
Hpv Dna ◽  
P16ink4a Expression ◽  
Hpv Status ◽  
Tumor Biopsies ◽  
Turkish Patients

Human papillomavirus (HPV)-associated tumors account for a significant proportion of head and neck squamous cell carcinomas (HNSCC) in developed countries. In recent years, there has been a rise of HPV infections associated with HNSCC, especially HPV16, which is the most commonly detected type in oral and oropharyngeal cancers. To investigate the frequency of HPV-driven HNSCC among patients living in Turkey, HPV DNA positivity and p16INK4A expression were assessed in primary tumor biopsies (n = 106). Eighteen out of one hundred and six (19%) HNSCC tumors showed p16INK4A overexpression, and 26/106 cases (24.5%) were positive for HPV DNA. Sixteen out of twenty-six samples were positive for both HPV DNA and p16INK4A staining. HPV16 could be isolated from 22/26 samples (84.6%) and was found to be the most frequently detected HPV type. This study represents the largest cohort of Turkish patients with HNSCC characterized according to HPV status and p16INK4A expression. Our data suggest that HPV16 infection, along with smoking, contribute to the development of HNSCC.

scholarly journals Cytological physiognomies and genotype distribution of human papillomaviruses among HPV/HIV co-infected and HPV mono-infected women

2021 ◽  
Vol 21 (1) ◽  
pp. 254-62
Author(s):  
Lucy Wanja Karani ◽  
Stanslaus Musyoki ◽  
Robert Orina ◽  
Christopher Khayeka-Wandabwa ◽  
Benuel Nyagaka
Keyword(s):  
Human Papillomavirus ◽  
Human Papillomaviruses ◽  
Low Grade ◽  
Genotype Distribution ◽  
Hpv 16 ◽  
Vaccination Programs ◽  
Immunodeficiency Virus ◽  
Prophylactic Vaccination ◽  
Intraepithelial Lesion ◽  
Control Study

Background: Co-infection of High Risk Human Papillomavirus (HR-HPV) and HIV is thought to favour initiation of intraepithelial squamous cell lesion and subsequent progression to cervical carcinoma. Objectives: Evaluation of cytological physiognomies in relation to possible age influence and the genotype distribution of human papillomaviruses among HPV/HIV co-infected and HPV monoinfected women in Kisii, Kenya. Methods: The case-control study enrolled 42 HPV/HIV co-infected and 42 HPV monoinfected women. Cervical swabs were collected in ThinPrep vials for HPV tying and cytological analysis. HPV subtypes were assayed by Xpert® HPV system (GXHPV-CE-10). Results: Mono-infected women aged 30-39 years had the highest proportion of low grade squamous intraepithelial lesion (LSIL) at 14 (16.67%) while the co-infected aged 50-59 years had the highest proportion of high grade squamous intraepi- thelial lesion (HSIL) at 9 (10.71%). HPV-16 genotype was the most predominant and it increased with age rise. Older coin- fected and mono-infected women (>40 years) had HSIL and LSIL as the most predominant cytological grade respectively. Conclusion: The predominance of HPV-16 and HPV-18/45 genotypes in the study setting is a consideration that would benefit targeted prophylactic vaccination programs. HPV testing and cervical cancer screening for young and older women on a regular basis ought to be reinforced. Keywords: Human immunodeficiency virus (HIV); Human Papillomavirus (HPV); co-infection; genotype; cytology.

scholarly journals Distribution and Prevalence of High-Risk Human Papillomavirus Genotypes in Cervical Specimens

2020 ◽  
Vol 25 (3) ◽  
pp. 325-331
Author(s):  
Erkan Özmen ◽  
Ülkü Altoparlak ◽  
Muhammet Hamidullah Uyanık ◽  
Abdulkadir Gülen
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Age Groups ◽  
Hpv Infection ◽  
High Rate ◽  
Genotype Distribution ◽  
Hpv Dna ◽  
Hpv Test ◽  
Significant Difference ◽  
Hpv Types

Introduction: Human papillomavirus (HPV) is frequently a sexually transmitted virus and can cause cervical cancer in women. Cervical cancer is the second most common type of cancer among the developing countries. In this study, cervical HPV DNA positivity and genotype distributions were investigated in female patients living in our region and the results were compared with different studies. Materials and Methods: Between 1 July, 2017 and 1 March, 2019, 433 cervical swabs were sent to Ataturk University, Medical Faculty Hospital, Medical Microbiology Laboratory due to suspicion of HPV. Swab samples were evaluated for HPV virus using molecular (Polymerase Chain Reaction-PCR) methods. For this purpose, Xpert HPV Test (Cepheid, Inc, Sunnyvale, CA) was used to identify HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68 t in a single sample. Results: Mean age of the patients ranged from 20 to 69 years, with a mean of 39.8 years (± 10.0). Positivity was detected in 62 of the 433 patients. Mean age of the positive patients was 40.2 years (± 11.3). When the positive patients were examined in terms of HPV types, the presence of HPV 16 was observed with a rate of 25.6%, while the HPV 18/45 types were found to be 9.0% in total. When patients were evaluated according to age groups, HPV DNA positivity was highest in the 25-34 age group with 38.7%. In our statistical study, there was no significant difference in HPV DNA positivity rate between the ages of 35 and under 35 years. Conclusion: This study demonstrates the prevalence and viral genotype distribution of HPV infection in women in Erzurum region. HPV type 16 is seen with a high rate in our region.

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