DC and RF /analog parameters in Ge‐source split drain ‐ZHP‐TFET : Drain and pocket engineering technique

Author(s):  
Rajesh Saha ◽  
Deepak Kumar Panda ◽  
Rupam Goswami ◽  
Brinda Bhowmick ◽  
Srimanta Baishya
2021 ◽  
Vol 1057 (1) ◽  
pp. 012029
Author(s):  
E Jayakiran Reddy ◽  
N Bhanodaya Kiran Babu ◽  
A Bala Raju

Biomolecules ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1162
Author(s):  
Seohyun Kim ◽  
Sangmin Ji ◽  
Hye Ran Koh

Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system has recently gained growing attention as a diagnostic tool due to its capability of specific gene targeting. It consists of Cas enzymes and a guide RNA (gRNA) that can cleave the target DNA or RNA based on the sequence of the gRNA, making it an attractive genetic engineering technique. In addition to the target-specific binding and cleavage, the trans-cleavage activity was reported for some Cas proteins, including Cas12a and Cas13a, which is to cleave the surrounding single-stranded DNA or RNA upon the target binding of Cas-gRNA complex. All these activities of the CRISPR-Cas system are based on its target-specific binding, making it applied to develop diagnostic methods by detecting the disease-related gene as well as microRNAs and the genetic variations such as single nucleotide polymorphism and DNA methylation. Moreover, it can be applied to detect the non-nucleic acids target such as proteins. In this review, we cover the various CRISPR-based diagnostic methods by focusing on the activity of the CRISPR-Cas system and the form of the target. The CRISPR-based diagnostic methods without target amplification are also introduced briefly.


2003 ◽  
Vol 47 (02) ◽  
pp. 83-91
Author(s):  
L. Belenkiy ◽  
Y. Raskin

The paper examines an effect of shear forces on limit load for I-section beams carrying later alloads. The problem is solve don the basis of a physical model, which enables one to take into account the effect of a resistance of beam flanges to the plastic shears train in the web of the beam. The physical model for the evaluation of limit loads was veriŽed using nonlinear finite element analysis. An engineering technique for the calculation of limit loads for shiphull beams subjected to large shear forces was developed using this model. As illustrative examples, the paper shows the application of the proposed technique to obtain closed-form solutions for the prediction of limit loads.


2016 ◽  
Author(s):  
Daniele Visioni ◽  
Giovanni Pitari ◽  
Valentina Aquila

Abstract. Sulfate geoengineering has been proposed as an affordable and climate-effective means for temporarily offset the warming produced by the increase of well mixed greenhouse gases (WMGHG). This climate engineering technique has been planned for a timeframe of a few decades needed to implement global inter-governmental measures needed to achieve stabilization of the atmospheric content of WMGHGs (CO2 in particular). The direct radiative effects of sulfur injection in the tropical lower stratosphere can be summarized as increasing shortwave scattering with consequent tropospheric cooling and increasing long- wave absorption with stratospheric warming. Indirect radiative effects are related to induced changes in the ozone distribution, stratospheric water vapor abundance, formation and size of upper tropospheric cirrus ice particles and lifetime of longlived species, namely CH4 in connection with OH changes through several photochemical mechanisms. A direct comparison of the net effects of WMGHG increase with direct and indirect effects of sulfate geoengineering may help fine-tune the best amount of sulfate to be injected in an eventual realization of the experiment. However, we need to take into account large uncertainties in the estimate of some of these aerosol effects, such as cirrus ice particle size modifications.


2021 ◽  
Vol 3 (4) ◽  
pp. 922-945
Author(s):  
Shaw-Hwa Lo ◽  
Yiqiao Yin

Text classification is a fundamental language task in Natural Language Processing. A variety of sequential models are capable of making good predictions, yet there is a lack of connection between language semantics and prediction results. This paper proposes a novel influence score (I-score), a greedy search algorithm, called Backward Dropping Algorithm (BDA), and a novel feature engineering technique called the “dagger technique”. First, the paper proposes to use the novel influence score (I-score) to detect and search for the important language semantics in text documents that are useful for making good predictions in text classification tasks. Next, a greedy search algorithm, called the Backward Dropping Algorithm, is proposed to handle long-term dependencies in the dataset. Moreover, the paper proposes a novel engineering technique called the “dagger technique” that fully preserves the relationship between the explanatory variable and the response variable. The proposed techniques can be further generalized into any feed-forward Artificial Neural Networks (ANNs) and Convolutional Neural Networks (CNNs), and any neural network. A real-world application on the Internet Movie Database (IMDB) is used and the proposed methods are applied to improve prediction performance with an 81% error reduction compared to other popular peers if I-score and “dagger technique” are not implemented.


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