Malignant neoplasms associated with orthopedic implant materials in rats

1986 ◽  
Vol 4 (3) ◽  
pp. 346-355 ◽  
Author(s):  
Vincent A. Memoli ◽  
Robert M. Urban ◽  
Joseph Alroy ◽  
Jorge O. Galante
Keyword(s):  
Malignant Neoplasms ◽  
Orthopedic Implant ◽  
Implant Materials

scholarly journals Recent Developments in Coatings for Orthopedic Metallic Implants

Coatings ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 791
Author(s):  
Muzamil Hussain ◽  
Syed Hasan Askari Rizvi ◽  
Naseem Abbas ◽  
Uzair Sajjad ◽  
Muhammad Rizwan Shad ◽  
...  
Keyword(s):  
Stress Shielding ◽  
Orthopedic Implant ◽  
Coating Materials ◽  
Implant Materials ◽  
Metallic Implants ◽  
Common Causes ◽  
Recent Developments ◽  
Orthopedic Applications ◽  
The Impact ◽  
Cocrmo Alloys

Titanium, stainless steel, and CoCrMo alloys are the most widely used biomaterials for orthopedic applications. The most common causes of orthopedic implant failure after implantation are infections, inflammatory response, least corrosion resistance, mismatch in elastic modulus, stress shielding, and excessive wear. To address the problems associated with implant materials, different modifications related to design, materials, and surface have been developed. Among the different methods, coating is an effective method to improve the performance of implant materials. In this article, a comprehensive review of recent studies has been carried out to summarize the impact of coating materials on metallic implants. The antibacterial characteristics, biodegradability, biocompatibility, corrosion behavior, and mechanical properties for performance evaluation are briefly summarized. Different effective coating techniques, coating materials, and additives have been summarized. The results are useful to produce the coating with optimized properties.

Multifunctionality of Perovskites BaTiO3 and CaTiO3 in a Composite with Hydroxyapatite as Orthopedic Implant Materials

2011 ◽  
Vol 131 (1) ◽  
pp. 119-126 ◽  
Author(s):  
A. K. Dubey ◽  
B. Basu ◽  
K. Balani ◽  
R. Guo ◽  
A. S. Bhalla
Keyword(s):  
Orthopedic Implant ◽  
Implant Materials

scholarly journals Wear and damage of articular cartilage with friction against orthopedic implant materials

2015 ◽  
Vol 48 (10) ◽  
pp. 1957-1964 ◽  
Author(s):  
Sevan R. Oungoulian ◽  
Krista M. Durney ◽  
Brian K. Jones ◽  
Christopher S. Ahmad ◽  
Clark T. Hung ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Orthopedic Implant ◽  
Implant Materials

Bio-Fabrication of Nacre on Conventional Implant Materials

2012 ◽  
Vol 529-530 ◽  
pp. 255-260
Author(s):  
Millie Kwan ◽  
Ri Zhi Wang
Keyword(s):  
High Density Polyethylene ◽  
Bone Growth ◽  
Orthopedic Implants ◽  
Titanium Implants ◽  
Orthopedic Implant ◽  
Entire Surface ◽  
Implant Materials ◽  
Growing Period ◽  
Biomineralization Process ◽  
Surface Morphologies

Nacreous coatings on orthopedic implants can be advantageous because of its robust mechanical properties, high biocompatibility, and ability to promote bone growth. The biofabrication of nacreous coatings on conventional orthopedic implant materials via biomineralization process from abalone shells was examined. The objective was to investigate the effect of different materials on nacreous coating growth. The coatings were characterized by SEM/EDS and XRD. It was found that different materials resulted in different surface morphologies and coating thicknesses, although the main mineral formed was aragonite. Calcium carbonate coating was formed on the entire surface of the poly (methyl methacrylate) and high density polyethylene implants and resulted in a thick coating, while the titanium implants showed thinner coating at the same growing period.

scholarly journals Sphingosine is able to prevent and eliminate Staphylococcus epidermidis biofilm formation on different orthopedic implant materials in vitro

2019 ◽  
Vol 98 (2) ◽  
pp. 209-219 ◽  
Author(s):  
Sascha Beck ◽  
Carolin Sehl ◽  
Sylvia Voortmann ◽  
Hedda Luise Verhasselt ◽  
Michael J. Edwards ◽  
...  
Keyword(s):  
Joint Replacement ◽  
Staphylococcus Epidermidis ◽  
Biofilm Formation ◽  
Orthopedic Implants ◽  
Antimicrobial Efficacy ◽  
Orthopedic Implant ◽  
Implant Materials ◽  
Joint Replacement Surgery ◽  
Replacement Surgery

Abstract Periprosthetic infection (PPI) is a devastating complication in joint replacement surgery. On the background of an aging population, the number of joint replacements and associated complications is expected to increase. The capability for biofilm formation and the increasing resistance of different microbes to antibiotics have complicated the treatment of PPI, requiring the need for the development of alternative treatment options. The bactericidal effect of the naturally occurring amino alcohol sphingosine has already been reported. In our study, we demonstrate the antimicrobial efficacy of sphingosine on three different strains of biofilm producing Staphylococcus epidermidis, representing one of the most frequent microbes involved in PPI. In an in vitro analysis, sphingosine’s capability for prevention and treatment of biofilm-contamination on different common orthopedic implant surfaces was tested. Coating titanium implant samples with sphingosine not only prevented implant contamination but also revealed a significant reduction of biofilm formation on the implant surfaces by 99.942%. When testing the antimicrobial efficacy of sphingosine on sessile biofilm-grown Staphylococcus epidermidis, sphingosine solution was capable to eliminate 99.999% of the bacteria on the different implant surfaces, i.e., titanium, steel, and polymethylmethacrylate. This study provides evidence on the antimicrobial efficacy of sphingosine for both planktonic and sessile biofilm-grown Staphylococcus epidermidis on contaminated orthopedic implants. Sphingosine may provide an effective and cheap treatment option for prevention and reduction of infections in joint replacement surgery. Key messages • Here we established a novel technology for prevention of implant colonization by sphingosine-coating of orthopedic implant materials. • Sphingosine-coating of orthopedic implants prevented bacterial colonization and significantly reduced biofilm formation on implant surfaces by 99.942%. • Moreover, sphingosine solution was capable to eliminate 99.999% of sessile biofilm-grown Staphylococcus epidermidis on different orthopedic implant surfaces.

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