scholarly journals Skeletal Muscle Wasting After Severe Burn is a Consequence of Cachexia and Sarcopenia

2021 ◽  
Author(s):  
Juquan Song ◽  
Audra Clark ◽  
Charles E Wade ◽  
Steven E Wolf
Keyword(s):  
Skeletal Muscle ◽  
Muscle Wasting ◽  
Severe Burn ◽  
Skeletal Muscle Wasting

scholarly journals ER stress and subsequent activated calpain play a pivotal role in skeletal muscle wasting after severe burn injury

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0186128 ◽  
Author(s):  
Li Ma ◽  
Wanli Chu ◽  
Jiake Chai ◽  
Chuanan Shen ◽  
Dawei Li ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Er Stress ◽  
Muscle Wasting ◽  
Burn Injury ◽  
Pivotal Role ◽  
Severe Burn ◽  
Skeletal Muscle Wasting ◽  
Severe Burn Injury

The ubiquitin–proteasome system and skeletal muscle wasting

2005 ◽  
Vol 41 (1) ◽  
pp. 173 ◽  
Author(s):  
Didier Attaix ◽  
Sophie Ventadour ◽  
Audrey Codran ◽  
Daniel Béchet ◽  
Daniel Taillandier ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Wasting ◽  
Ubiquitin Proteasome System ◽  
Skeletal Muscle Wasting ◽  
Ubiquitin Proteasome

scholarly journals Mitochondrial Dysfunction Is a Common Denominator Linking Skeletal Muscle Wasting Due to Disease, Aging, and Prolonged Inactivity

Antioxidants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 588
Author(s):  
Hayden W. Hyatt ◽  
Scott K. Powers
Keyword(s):  
Skeletal Muscle ◽  
Mitochondrial Dysfunction ◽  
Chronic Diseases ◽  
Muscle Mass ◽  
Cancer Chemotherapy ◽  
Muscle Wasting ◽  
The Body ◽  
Common Denominator ◽  
Skeletal Muscle Wasting ◽  
Vital Functions

Skeletal muscle is the most abundant tissue in the body and is required for numerous vital functions, including breathing and locomotion. Notably, deterioration of skeletal muscle mass is also highly correlated to mortality in patients suffering from chronic diseases (e.g., cancer). Numerous conditions can promote skeletal muscle wasting, including several chronic diseases, cancer chemotherapy, aging, and prolonged inactivity. Although the mechanisms responsible for this loss of muscle mass is multifactorial, mitochondrial dysfunction is predicted to be a major contributor to muscle wasting in various conditions. This systematic review will highlight the biochemical pathways that have been shown to link mitochondrial dysfunction to skeletal muscle wasting. Importantly, we will discuss the experimental evidence that connects mitochondrial dysfunction to muscle wasting in specific diseases (i.e., cancer and sepsis), aging, cancer chemotherapy, and prolonged muscle inactivity (e.g., limb immobilization). Finally, in hopes of stimulating future research, we conclude with a discussion of important future directions for research in the field of muscle wasting.

scholarly journals Negative Impact of Skeletal Muscle Wasting After Neoadjuvant Chemotherapy Followed by Surgery on Survival for Patients with Thoracic Esophageal Cancer

2017 ◽  
Vol 24 (12) ◽  
pp. 3741-3747 ◽  
Author(s):  
Shuhei Mayanagi ◽  
Yasuhiro Tsubosa ◽  
Katsuhiro Omae ◽  
Masahiro Niihara ◽  
Tsuneyuki Uchida ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Esophageal Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Muscle Wasting ◽  
Negative Impact ◽  
Thoracic Esophageal Cancer ◽  
Skeletal Muscle Wasting

scholarly journals MIR-190B Alleviates Cell Autophagy and Burn-Induced Skeletal Muscle Wasting via Modulating PHLPP1/Akt/FoxO3A Signaling Pathway

Shock ◽  
2019 ◽  
Vol 52 (5) ◽  
pp. 513-521 ◽  
Author(s):  
Yonghui Yu ◽  
Longlong Yang ◽  
Shaofang Han ◽  
Yushou Wu ◽  
Lingying Liu ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Signaling Pathway ◽  
Muscle Wasting ◽  
Skeletal Muscle Wasting

scholarly journals Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

2021 ◽  
Author(s):  
Jorne Ubachs ◽  
Wouter R.P.H. Worp ◽  
Rianne D.W. Vaes ◽  
Kenneth Pasmans ◽  
Ramon C. Langen ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Skeletal Muscle ◽  
Muscle Wasting ◽  
Skeletal Muscle Wasting
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