Application of the normalized relative error distribution analysis for non‐destructive quality control of drugs by Raman spectroscopy

2019 ◽  
Vol 50 (10) ◽  
pp. 1614-1623 ◽  
Author(s):  
Roman R. Galeev ◽  
Anatoly A. Saveliev ◽  
Ekaterina V. Galeeva ◽  
Tatyana S. Falaleeva ◽  
Ilshat R. Aryslanov ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Quality Control ◽  
Relative Error ◽  
Error Distribution ◽  
Distribution Analysis ◽  
Non Destructive

Analysis of Phthalate Ester Content in Polyvinylchloride Construction Plastics by RAMAN Spectroscopy

2019 ◽  
Vol 806 ◽  
pp. 113-117
Author(s):  
Alexander Mikhailovich Zakharenko ◽  
Kirill Sergeevich Golokhvast
Keyword(s):  
Raman Spectroscopy ◽  
Quality Control ◽  
Polyvinyl Chloride ◽  
Phthalate Ester ◽  
Production Lines ◽  
Ester Content ◽  
Remote Determination ◽  
Non Destructive ◽  
Ethylhexyl Phthalate

There is serious concern that fat-soluble phthalates such as di (2-ethylhexyl) phthalate, or DEPH. Phthalates are not chemically bonded to the PVC and will with time escape by evaporation or by extraction when in contact with liquids. Raman spectroscopy excited with a 785 nm laser can be used to determine the content of plasticizers in commercial flexible polyvinyl chloride (PVC) construction plastics. This method is very convenient for rapid non-destructive remote determination of phthalates, such as for quality control of production lines, quality control or at customs.

scholarly journals Moisture Measurement in Paper and Cardboard Packaging Waste Bales for Recycling

2021 ◽  
Vol 11 (10) ◽  
pp. 4586
Author(s):  
Ana Silveira ◽  
João Cardoso ◽  
Maria José Correia ◽  
Graça Martinho
Keyword(s):  
Quality Control ◽  
Dielectric Properties ◽  
Moisture Content ◽  
Reliable Method ◽  
Drying Method ◽  
Waste Streams ◽  
Oven Drying ◽  
Quality Issue ◽  
Commercial Device ◽  
Non Destructive

Moisture content is a quality issue raised by recycling plants in the acceptance of paper and cardboard coming from waste streams. The current way to measure this parameter is by the oven drying method, which is a slow and invasive process, costing time and resources for the recyclers to do this type of quality control. An alternative to such a measurement technique is the use of plate-form devices which indirectly measure the moisture content using the dielectric properties of water and paper. This study has tested this method and developed a representative equation for the use of devices with these properties in the Portuguese market. For that, 48 wastepaper and cardboard bales were tested with both the traditional (oven drying) method and a commercial device equipped with dielectric technology. An equation that fits the studied reality (R2 = 0.76) was achieved, and possible problems regarding the use of this device were tested. The results showed that this type of device could be used as a time- and cost-saving, non-destructive and reliable method in the quality control of wastepaper and cardboard bales.

Optical Diagnostics of Microstructures Fabricated Using Quantum Well Intermixing

1999 ◽  
Vol 607 ◽  
Author(s):  
A. Saher Helmy ◽  
A.C. Bryce ◽  
C.N. Ironside ◽  
J.S. Aitchison ◽  
J.H. Marsh ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Quantum Well ◽  
Spatial Resolution ◽  
Optical Diagnostics ◽  
Complete Suppression ◽  
Quantum Well Intermixing ◽  
Spatially Resolved ◽  
Non Destructive ◽  
Insight Into ◽  
Free Vacancy

AbstractIn this paper we shall discuss techniques for accurate, non-destructive, optical characterisation of structures fabricated using quantum well intermixing (QWI). Spatially resolved photoluminescence and Raman spectroscopy were used to characterise the lateral bandgap profiles produced by impurity free vacancy disordering (IFVD) technology. Different features were used to examine the spatial resolution of the intermixing process. Features include 1:1 gratings as well as isolated stripes. From the measurements, the spatial selectivity of IFVD could be identified, and was found to be ∼4.5 μm, in contrast with the spatial resolution of the process of sputtering induced intermixing, which was found to be ∼2.5 μm. In addition, PL measurements on 1:1 gratings fabricated using IFVD show almost complete suppression of intermixing dielectric cap gratings with periods less than 10 microns. Finally, some insight into the limitations and merits of PL and Raman for the precision characterisation of QWI will be presented.

Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes

2016 ◽  
Vol 90 ◽  
pp. 85-95 ◽  
Author(s):  
Marten Klukkert ◽  
Jian X. Wu ◽  
Jukka Rantanen ◽  
Jens M. Carstensen ◽  
Thomas Rades ◽  
...  
Keyword(s):  
Quality Control ◽  
Uv Imaging ◽  
Non Destructive

scholarly journals In situ Analytical Quality Control of chemotherapeutic solutions in infusion bags by Raman spectroscopy

Talanta ◽  
2021 ◽  
Vol 228 ◽  
pp. 122137
Author(s):  
Alaa A. Makki ◽  
Suha Elderderi ◽  
Victor Massot ◽  
Renaud Respaud ◽  
Hugh.J. Byrne ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Quality Control ◽  
Analytical Quality Control ◽  
Analytical Quality

Development of Deep Learning Algorithms to Discriminate Giant Cell Tumor of Bone from Adjacent Normal Tissues by Confocal Raman Spectroscopy

The Analyst ◽  
2022 ◽  
Author(s):  
Carol PY Lau ◽  
Wenao Ma ◽  
Kwan Yau Law ◽  
Maribel Lacambra ◽  
Kwok Chuen Wong ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Chemical Structure ◽  
Cell Tumor ◽  
Confocal Raman Spectroscopy ◽  
Normal Tissues ◽  
Analysis Technique ◽  
Destructive Analysis ◽  
Non Destructive

Raman spectroscopy is a non-destructive analysis technique that provides detailed information about the chemical structure of the tumor. Raman spectra of 52 giant cell tumor of bone (GCTB), and 21...

scholarly journals Raman spectroscopy as a tool for ecology and evolution

2017 ◽  
Vol 14 (131) ◽  
pp. 20170174 ◽  
Author(s):  
Arno Germond ◽  
Vipin Kumar ◽  
Taro Ichimura ◽  
Jerome Moreau ◽  
Chikara Furusawa ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Low Cost ◽  
Biological Systems ◽  
Spectral Information ◽  
Selective Pressures ◽  
Biological Features ◽  
Microscopy Technique ◽  
Pragmatic Aspects ◽  
Non Destructive

Scientists are always on the lookout for new modalities of information which could reveal new biological features that are useful for deciphering the complexity of biological systems. Here, we introduce Raman spectroscopy as a prime candidate for ecology and evolution. To encourage the integration of this microscopy technique in the field of ecology and evolution, it is crucial to discuss first how Raman spectroscopy fits within the conceptual, technical and pragmatic considerations of ecology and evolution. In this paper, we show that the spectral information holds reliable indicators of intra- and interspecies variations, which can be related to the environment, selective pressures and fitness. Moreover, we show how the technical and pragmatic aspects of this modality (non-destructive, non-labelling, speed, relative low cost, etc.) enable it to be combined with more conventional methodologies. With this paper, we hope to open new avenues of research and extend the scope of available methodologies used in ecology and evolution.

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