“Paradoxical Kinesis” is not a Hallmark of Parkinson's disease but a general property of the motor system

2006 ◽  
Vol 21 (9) ◽  
pp. 1490-1495 ◽  
Author(s):  
Bénédicte Ballanger ◽  
Stéphane Thobois ◽  
Pierre Baraduc ◽  
Robert S. Turner ◽  
Emmanuel Broussolle ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
General Property ◽  
Motor System

scholarly journals Aesthetics in motion: The beauty of action paintings as revealed by Parkinson’s disease

2020 ◽  
Author(s):  
Stacey Humphries ◽  
Jacqueline Rick ◽  
Daniel Weintraub ◽  
Anjan Chatterjee
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor System ◽  
Aesthetic Judgment ◽  
Aesthetic Appreciation ◽  
Visual Metaphor ◽  
Embodied Simulation ◽  
Aesthetic Experiences ◽  
Subjective Value ◽  
The Aesthetic

Visual art offers cognitive neuroscience an opportunity to study how subjective value is constructed from representations supported by multiple neural systems. A surprising finding in research on aesthetic judgment is that functional activation of motor areas of the brain often occurs in response to static, abstract stimuli, such as paintings. This motor activity has variously been hypothesised to reflect the embodied simulation of an artist’s painting movements or emotions, as well as possible preparatory approach-avoidance responses to liked and disliked artworks. However, whether this motor involvement functionally contributes to aesthetic appreciation has not been addressed. Here, we examined whether motor system dysfunction alters the aesthetic experiences of patients with Parkinson’s disease. 43 people with Parkinson’s disease and 40 controls made preference decisions and rated the motion content and their aesthetic appreciation of a set of high-motion action paintings (by Jackson Pollock) and a set of low-motion neoplastic paintings (by Piet Mondrian). People with Parkinson’s disease demonstrated stable and internally consistent preferences for abstract art, but their perception of movement in the paintings was significantly lower in both conditions than that of controls. In addition, people with Parkinson’s demonstrated enhanced preferences for high-motion art, and a fundamentally altered relationship between motion and aesthetic appreciation. Our results do not accord well with a straightforward embodied simulation account of aesthetic experiences, because artworks that did not include visual traces of the artist’s actions were still experienced as lower in motion by Parkinson’s patients. We suggest that the ability to form movement representations from static abstract images is more akin to a process of visual metaphor comprehension that is mediated through the motor system. Overall, we find support for hypotheses linking motion, motor responses and aesthetic appreciation, and provide clear evidence that altered neural functioning changes the way art is perceived and valued.

Reorganization of Motor System in Parkinson’s Disease

2011 ◽  
Vol 66 (4) ◽  
pp. 220-226 ◽  
Author(s):  
Zsuzsanna Kalmar ◽  
Norbert Kovacs ◽  
Gabor Perlaki ◽  
Ferenc Nagy ◽  
Zsuzsanna Aschermann ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor System

scholarly journals An Immersive Virtual Reality Exergame for People with Parkinson’s Disease

2020 ◽  
pp. 138-145
Author(s):  
Weiqin Chen ◽  
Martin Bang ◽  
Daria Krivonos ◽  
Hanna Schimek ◽  
Arnau Naval
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Virtual Reality ◽  
Physical Exercise ◽  
Cognitive Rehabilitation ◽  
Motor System ◽  
Neurodegenerative Disorder ◽  
Evidence Based ◽  
Immersive Virtual Reality

AbstractParkinson’s disease is a neurodegenerative disorder that affects primarily motor system. Physical exercise is considered important for people with Parkinson’s disease (PD) to slow down disease progression and maintain abilities and quality of life. However, people with PD often experience barriers to exercises that causes low-level adherence to exercise plans and programs. Virtual Reality (VR) is an innovative and promising technology for motor and cognitive rehabilitation. Immersive VR exergames have potential advantages by allowing for individualized skill practice in a motivating interactive environment without distractions from outside events. This paper presents an immersive virtual reality (VR) exergame aiming at motor training on fingers and hand-and-eye coordination. The results from the usability study indicate that immersive VR exergames have potential to provide motivating and engaging physical exercise for people with PD. Through this research, we hope to contribute to evidence-based design principles for task-specific immersive VR exergames for patients with Parkinson’s Disease.

Altered functional organization of the motor system related to ankle movements in Parkinson’s disease: insights from functional MRI

2011 ◽  
Vol 118 (5) ◽  
pp. 783-793 ◽  
Author(s):  
Petra Katschnig ◽  
Petra Schwingenschuh ◽  
Margit Jehna ◽  
Martin Švehlík ◽  
Katja Petrovic ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Functional Mri ◽  
Motor System ◽  
Functional Organization

scholarly journals A systematic review of MEG‐based studies in Parkinson's disease: The motor system and beyond

2019 ◽  
Vol 40 (9) ◽  
pp. 2827-2848 ◽  
Author(s):  
Lennard I. Boon ◽  
Victor J. Geraedts ◽  
Arjan Hillebrand ◽  
Martijn R. Tannemaat ◽  
Maria Fiorella Contarino ◽  
...  
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor System

P2.038 Effect of electrode implantation to STN on motor system in Parkinson's disease: a fMRI study

2009 ◽  
Vol 15 ◽  
pp. S98
Author(s):  
R. Jech ◽  
K. Müller ◽  
F. Růžička ◽  
D. Urgošík ◽  
D. Medenwald ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor System ◽  
Electrode Implantation ◽  
Fmri Study

scholarly journals The Function of the Metals in Regulating Epigenetics During Parkinson’s Disease

2021 ◽  
Vol 11 ◽  
Author(s):  
Xiangzhen Wei ◽  
Menghua Cai ◽  
Lifang Jin
Keyword(s):  
Parkinson’S Disease ◽  
Dna Methylation ◽  
Central Nervous System ◽  
Parkinson's Disease ◽  
Nervous System ◽  
Histone Modification ◽  
Motor System ◽  
Epigenetic Mechanism ◽  
Epigenetic Mechanisms ◽  
Global Hypomethylation

Parkinson’s means Parkinson’s disease, a chronic degenerative disease of central nervous system. The main area which is affected by this disease is motor system. Since it firstly founded by James Parkinson in his 1817 publication, nowadays, people still have lots of questions about this disease. This review mainly summarizes the epigenetics of Parkinson’s. DNA methylation is one of the epigenetic mechanisms of Parkinson’s. During the development of disease, global hypomethylation, and hypermethylation happen in different areas of patients. Another epigenetic mechanism is histone modification. People believe that some metals can induce Parkinson’s disease by modulating epigenetic mechanisms. This review summarizes the relationships between different metals and Parkinson’s disease. However, the specific roles of most metals in epigenetics are still unknown, which need further research.

Diagnosis of Parkinson’s Disease Using SVM Classifier

2020 ◽  
pp. 2150011
Author(s):  
G. Wiselin Jiji ◽  
A. Rajesh ◽  
P. Johnson Durai Raj
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Diagnosis ◽  
Active Contour ◽  
Motor System ◽  
Svm Classifier ◽  
Common Disease ◽  
Morphological Operation ◽  
Aged People ◽  
Speech Data

Parkinson’s disease (PD) is the most common disease that affects aged people which leads to dopamine-producing cells in substantia nigra to be damaged when motor system degenerates. Clinical Diagnosis of Parkinson’s disease at the earlier stage is very difficult. This work is carried out to find the significance of cognition function of basal ganglia (BG) region and speech data values. The BG can be segmented using morphological operation and active contour algorithm. Co-occurrences features are extracted and out of 720 features, the promising 110 features are selected using variance method. More promising 22 features are selected in speech data and both features are individually classified using SVM to find out the efficiency in Diagnosis. The outcome shows cognition function of BG performing a major role in early diagnosis of Parkinson’s disease when compared to speech data.

scholarly journals O método Lee Silverman para reabilitação da fala na doença de Parkinson

2001 ◽  
Vol 19 (3) ◽  
pp. 551-557
Author(s):  
Alice Estevo Dias ◽  
Hsin Fen Chien ◽  
Egberto Reis Barbosa
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor System ◽  
Voice Disorders ◽  
Speech Disorders ◽  
Voice Therapy ◽  
Lee Silverman Voice Treatment ◽  
Voice Treatment ◽  
Speech Motor

As alterações da fala (disfonia e disartria) frequentemente acompanham a evolução da doença de Parkinson (DP). Objetivo. Este estudo revisa o Método Lee Silverman, considerado o mais eficiente para a reabilitação das alterações da fala na DP e atualiza os avanços na sua aplicação. Método. Foi realizada uma pesquisa nas bases de dados MEDLINE, Pubmed e Bireme dos artigos indexados publicados de 1990 a 2010, com as seguintes palavras-chave: Parkinson’s disease, PD, Lee Silverman Voice Treatment, LSVT, LSVT LOUD, LSVT parkinson, voice treatment and PD, voice therapy and PD, communication and PD, dysarthria and PD, dysphonia and PD, speech disorders and PD, voice disorders and PD, hypophonia and PD, speech motor system and PD. Resultados. Na literatura, existe ampla descrição dos resultados de estudos do método Lee Silverman na DP. Os artigos encontrados evidenciam melhora da prosódia, articulação, ressonância, respiração, inteligibilidade, intensidade e qualidade da voz, assim como da deglutição e da expressividade facial. Conclusões. Para a reabilitação da fala dispõe-se de eficientes técnicas fonoaudiológicas. Contudo, conforme a literatura científica, o emprego do Método Lee Silverman é opção vantajosa, pois foi desenvolvido especificamente para a DP. Há inúmeras evidências de sua eficácia e vem sendo continuamente avaliado, ampliando sua aplicabilidade.

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