Neutron‐Gamma Dosimetry for BNCT using Field Oxide Transistors with Gadolinium Oxide as Neutron Converter Layer

The article discusses methods for optimizing the design of the Neutron Converter research plant design with parameters that are most suitable for a particular consumer. 38 similar plant structures with different materials and sources were calculated, on the basis of which the most optimal options were found. As part of the interaction between OKBM Afrikantov JSC and the Nizhny Novgorod State Technical University named after R. E. Alekseev, the Neutron Converter research plant was designed and assembled. The universal neutron converter is a device for converting a stream of fast neutrons emitted by isotopic sources into a "standardized" value of flux density with known parameters in the volume of the central part of the product, which is the working part of the universal neutron converter. To supply neutron converters to other customer organizations (universities, research organizations and collective centers), it is necessary to take into account the experience of operating an existing facility, as well as rationalize the design process of each specific instance in accordance with the requirements of the customer.

Gadolinium Oxide Nanoparticles as Potential Multimodal Imaging and Therapeutic Agents

Current Topics in Medicinal Chemistry ◽

10.2174/1568026611313040003 ◽

2013 ◽

Vol 13 (4) ◽

pp. 422-433 ◽

Cited By ~ 49

Author(s):

Tae Jeong Kim ◽

Kwon Seok Chae ◽

Yongmin Chang ◽

Gang Ho Lee

Keyword(s):

Multimodal Imaging ◽

Therapeutic Agents ◽

Gadolinium Oxide ◽

Oxide Nanoparticles ◽

Gadolinium Oxide Nanoparticles

Multifiller nanocomposites containing gadolinium oxide and bismuth nanoparticles with enhanced X‐ray attenuation property

Journal of Applied Polymer Science ◽

10.1002/app.51252 ◽

2021 ◽

pp. 51252

Author(s):

Sangeetha Jayakumar ◽

Vadivel Mani ◽

Thangavelu Saravanan ◽

Karunanithi Rajamanickam ◽

Alex Daniel Prabhu ◽

...

Keyword(s):

Gadolinium Oxide ◽

X Ray ◽

Bismuth Nanoparticles

Radiopharmaceutical and Eu3+ doped gadolinium oxide nanoparticles mediated triple-excited fluorescence imaging and image-guided surgery

Journal of Nanobiotechnology ◽

10.1186/s12951-021-00920-6 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Xiaojing Shi ◽

Caiguang Cao ◽

Zeyu Zhang ◽

Jie Tian ◽

Zhenhua Hu

Keyword(s):

Fluorescent Probes ◽

Signal Intensity ◽

Tumor Imaging ◽

Tumor Resection ◽

Optical Signal ◽

Gadolinium Oxide ◽

Image Guided Surgery ◽

Guided Surgery ◽

Image Guided ◽

The Impact

AbstractCerenkov luminescence imaging (CLI) is a novel optical imaging technique that has been applied in clinic using various radionuclides and radiopharmaceuticals. However, clinical application of CLI has been limited by weak optical signal and restricted tissue penetration depth. Various fluorescent probes have been combined with radiopharmaceuticals for improved imaging performances. However, as most of these probes only interact with Cerenkov luminescence (CL), the low photon fluence of CL greatly restricted it’s interaction with fluorescent probes for in vivo imaging. Therefore, it is important to develop probes that can effectively convert energy beyond CL such as β and γ to the low energy optical signals. In this study, a Eu3+ doped gadolinium oxide (Gd2O3:Eu) was synthesized and combined with radiopharmaceuticals to achieve a red-shifted optical spectrum with less tissue scattering and enhanced optical signal intensity in this study. The interaction between Gd2O3:Eu and radiopharmaceutical were investigated using 18F-fluorodeoxyglucose (18F-FDG). The ex vivo optical signal intensity of the mixture of Gd2O3:Eu and 18F-FDG reached 369 times as high as that of CLI using 18F-FDG alone. To achieve improved biocompatibility, the Gd2O3:Eu nanoparticles were then modified with polyvinyl alcohol (PVA), and the resulted nanoprobe PVA modified Gd2O3:Eu (Gd2O3:Eu@PVA) was applied in intraoperative tumor imaging. Compared with 18F-FDG alone, intraoperative administration of Gd2O3:Eu@PVA and 18F-FDG combination achieved a much higher tumor-to-normal tissue ratio (TNR, 10.24 ± 2.24 vs. 1.87 ± 0.73, P = 0.0030). The use of Gd2O3:Eu@PVA and 18F-FDG also assisted intraoperative detection of tumors that were omitted by preoperative positron emission tomography (PET) imaging. Further experiment of image-guided surgery demonstrated feasibility of image-guided tumor resection using Gd2O3:Eu@PVA and 18F-FDG. In summary, Gd2O3:Eu can achieve significantly optimized imaging property when combined with 18F-FDG in intraoperative tumor imaging and image-guided tumor resection surgery. It is expected that the development of the Gd2O3:Eu nanoparticle will promote investigation and application of novel nanoparticles that can interact with radiopharmaceuticals for improved imaging properties. This work highlighted the impact of the nanoprobe that can be excited by radiopharmaceuticals emitting CL, β, and γ radiation for precisely imaging of tumor and intraoperatively guide tumor resection.

Effect of added gadolinium oxide on the thermal air oxidation of uranium dioxide

Journal of Nuclear Materials ◽

10.1016/j.jnucmat.2021.153008 ◽

2021 ◽

Vol 552 ◽

pp. 153008

Author(s):

Randall D. Scheele ◽

Brady D. Hanson ◽

Andrew M. Casella

Keyword(s):

Uranium Dioxide ◽

Gadolinium Oxide ◽

Air Oxidation

Hydration of gadolinium oxide ( GdOx ) and its effect on voltage-induced Co oxidation in a Pt/Co/GdOx/Au heterostructure

Physical Review Materials ◽

10.1103/physrevmaterials.3.064408 ◽

2019 ◽

Vol 3 (6) ◽

Cited By ~ 3

Author(s):

Aik Jun Tan ◽

Mantao Huang ◽

Sara Sheffels ◽

Felix Büttner ◽

Sunho Kim ◽

...

Keyword(s):

Co Oxidation ◽

Gadolinium Oxide

Activatable molecular MRI nanoprobe for tumor cell imaging based on gadolinium oxide and iron oxide nanoparticle

Biosensors and Bioelectronics ◽

10.1016/j.bios.2016.07.044 ◽

2016 ◽

Vol 86 ◽

pp. 1047-1053 ◽

Cited By ~ 18

Author(s):

Jingjing Li ◽

Shan Wang ◽

Chen Wu ◽

Yue Dai ◽

Pingfu Hou ◽

...

Keyword(s):

Iron Oxide ◽

Tumor Cell ◽

Cell Imaging ◽

Gadolinium Oxide ◽

Iron Oxide Nanoparticle ◽

Molecular Mri ◽

Oxide Nanoparticle

2D Gadolinium Oxide Nanoplates as T 1 Magnetic Resonance Imaging Contrast Agents

Advanced Healthcare Materials ◽

10.1002/adhm.202001780 ◽

2021 ◽

pp. 2001780

Author(s):

Gary Stinnett ◽

Nasim Taheri ◽

Jake Villanova ◽

Arash Bohloul ◽

Xiaoting Guo ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Contrast Agents ◽

Gadolinium Oxide ◽

Resonance Imaging ◽

Magnetic Resonance Imaging Contrast

Characterization of tunnel-oxide degradation due to plasma field oxide recess in flash memory devices

Thin Solid Films ◽

10.1016/j.tsf.2012.03.005 ◽

2012 ◽

Vol 520 (15) ◽

pp. 5007-5010 ◽

Cited By ~ 1

Author(s):

Jeungyun Lee ◽

Dong-Kwon Kim ◽

Gyung-Jin Min ◽

Ilsub Chung

Keyword(s):

Flash Memory ◽

Memory Devices ◽

Oxide Degradation ◽

Field Oxide