Fabrication of biodegradable poly(trimethylene carbonate) networks for potential tissue engineering scaffold applications

In this papers, the authors described a rapid prototyping method to produce vascularized tissue such liver scaffold for tissue engineering applications. A scaffold with interconnected channel was designed using CAD environment. The data were transferred to a Polyjet 3D Printing machine (Eden 250, Object, Israel) to generate the models. Based on the 3D Printing model, a PDMS (polydimethyl-silicone) mould was created which can be used to cast the biodegradable poly (L-lactic-co-glycolic acid) (PLGA )material. The advantages and limitations of Rapid Prototyping (RP) techniques as well as the future direction of RP development in tissue engineering scaffold fabrication were reviewed.

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Co-Electrospinning of Microbial Polyester/Gelatin and their Interaction with Fibroblasts

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.342-343.201 ◽

2007 ◽

Vol 342-343 ◽

pp. 201-204 ◽

Cited By ~ 3

Author(s):

So Hee Yun ◽

Ga Young Jun ◽

Kwan Han Yoon ◽

Yong Soon Park ◽

Young Jin Kim ◽

...

Keyword(s):

Tissue Engineering ◽

Cell Attachment ◽

Human Fibroblasts ◽

Average Diameter ◽

Tissue Engineering Scaffold ◽

Promising Method ◽

Initial Cell ◽

Electrospinning Method ◽

Biodegradable Poly ◽

Mediate Cell

Biodegradable poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanofibrous matrix containing gelatin was fabricated by electrospinning method. The average diameter of electrospun PHBV/Gelatin (1:1) nanofibers was 600 nm determined by FE-SEM. ATR-FTIR and ESCA measurements were used to confirm the presence of gelatin in PHBV/Gelatin nanofibers. Human fibroblasts' behavior on PHBV/Gelatin nanofibrous matrix has been investigated. Fibroblasts were well attached on the surface of control PHBV and PHBV/Gelatin nanofibers. Initial cell attachment on PHBV/Gelatin nanofibers was higher than that of control PHBV nanofibers. Gelatin has many RGD moiety that mediate cell attachment. From this reason, initial cell attachment increased on the surface of PHBV/Gelatin nanofibers. From the results, coelectrospinning of PHBV and gelatin is a promising method for tissue engineering scaffold.

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Strontium ranelate-loaded PLGA porous microspheres enhancing the osteogenesis of MC3T3-E1 cells

RSC Advances ◽

10.1039/c7ra01445g ◽

2017 ◽

Vol 7 (40) ◽

pp. 24607-24615 ◽

Cited By ~ 10

Author(s):

Zhenyang Mao ◽

Zhiwei Fang ◽

Yunqi Yang ◽

Xuan Chen ◽

Yugang Wang ◽

...

Keyword(s):

Tissue Engineering ◽

Strontium Ranelate ◽

Glycolic Acid ◽

Tissue Engineering Scaffold ◽

Porous Microspheres ◽

Biodegradable Poly

Biodegradable poly lactic-co-glycolic acid (PLGA) has been used as a tissue engineering scaffold as well as a carrier for the delivery of proteins, drugs, and other macromolecules.

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Poly(trimethylene carbonate) flexible intestinal anastomosis scaffolds to reduce the probability of intestinal fistula and obstruction

Journal of Materials Chemistry B ◽

10.1039/d1tb00759a ◽

2021 ◽

Author(s):

Yuehan Ren ◽

Xujian Li ◽

Lei Wu ◽

Luqi Pan ◽

Zhixiao Ji ◽

...

Keyword(s):

Tissue Engineering ◽

Digestive Tract ◽

Intestinal Anastomosis ◽

Tissue Engineering Scaffold ◽

Intestinal Fistula ◽

Trimethylene Carbonate ◽

Reconstruction Process ◽

Organizational Compliance

Biodegradable anastomat play an important role during the reconstruction process of digestive tract. However, the biocompatibility and organizational compliance of the anastomotic tubes still need be improved. Tissue engineering scaffold...

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Preparation and properties of a biodegradable poly(lactide-co-glycolide)/poly(trimethylene carbonate) porous composite scaffold for bone tissue engineering

New Journal of Chemistry ◽

10.1039/d0nj02921a ◽

2020 ◽

Vol 44 (34) ◽

pp. 14632-14641 ◽

Cited By ~ 1

Author(s):

Jin Qi ◽

Yu Zhang ◽

Xiliang Liu ◽

Qianmao Zhang ◽

Chengdong Xiong

Keyword(s):

Mechanical Properties ◽

Tissue Engineering ◽

Porous Scaffold ◽

Composite Scaffold ◽

High Porosity ◽

Trimethylene Carbonate ◽

Porous Composite ◽

Biodegradable Poly ◽

Good Biocompatibility ◽

Interconnected Pore

New biodegradable PLGA/PTMC composite porous scaffold with high porosity, mechanical properties, significant homogeneous, interconnected pore network and good biocompatibility.

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