scholarly journals Clinical profile of COVID‐positive children with cancer and their follow‐up: A tertiary care center's experience from a developing country

2021 ◽  
Author(s):  
Latha M. Sneha ◽  
M. U. Niranjani ◽  
J. Dhaarani ◽  
T. K. Balaji ◽  
Janani Arul ◽  
...  
Keyword(s):  
Developing Country ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Children With Cancer

Abstract 811: Natural History and Expanded Clinical Profile of Stress (Tako-Tsubo) Cardiomyopathy in United States Women

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Scott W Sharkey ◽  
Denise C Windenburg ◽  
Robert G Hauser ◽  
John R Lesser ◽  
Barry J Maron
Keyword(s):  
United States ◽  
Heart Failure ◽  
Cardiac Arrest ◽  
Troponin T ◽  
Tertiary Care ◽  
Left Ventricular ◽  
Stressful Events ◽  
Clinical Profile ◽  
Hospital Death

Stress cardiomyopathy (SC) is a newly reported condition of older women, triggered by emotionally and physically stressful events, characterized by acute heart failure with a distinctive angiographic profile, and regarded as a reversible process. To date, extended follow-up of SC patients is largely unavailable. We have assembled a substantial consecutive group of patients with SC to assess short and long-term clinical consequences of this condition. Between 2001–2008, we prospectively identified and followed (mean 2.0 years, range 0–6.7) 113 consecutive women with SC at a tertiary care United States hospital. Patients were female, aged 32–92 years (mean 68±13), and 16 (14%) were < 55 years. In 105 (93%) a triggering stressful event (emotional in 50, acute illness in 55) was identified; however, in 8 patients (7%) no such event preceded SC. The ECG showed ST-segment elevation in 58(51%) patients and ejection fraction (EF) was 31±11%. Troponin was elevated in 109 (96%); peak troponin (T) was 0.64±0.76 ng/ml. Of the 113 patients, 110(97%) survived the acute event: 3 patients (3%) died in-hospital (cardiogenic shock in 2; subarachnoid hemorrhage in 1). Other complications included: cardiac arrest 2 (2%), hypotension requiring inotropic drug and/or intra-aortic balloon pump in 22 (19%), pulmonary or cerebral embolism in 3 (3%), left ventricular (LV) or right ventricular thrombus in 7 (6%) and LV outflow obstruction in 13 (12%). CMR findings included absent delayed hyperenhancement (gadolinium) in 82/83 (99%), normal LV apical contraction in 46%, RV akinesia in 22%, and pleural effusions due to heart failure in 46%. At follow-up, EF returned to normal in all patients, but one or more SC events recurred in 7 (6%) patients (complicated by non-fatal cardiac arrest in 1), of whom 3 were taking beta-blockers. Post-hospital death occurred in 15 (13%) patients of which 14 were noncardiac and 1 of unknown cause. Among this large cohort of women, some SC events occurred atypically either without a stress trigger or in younger premenopausal patients. SC also led to death in the acute phase or to later non-fatal recurrences of SC or cardiac arrest in about 10%. Therefore, the clinical profile of SC is much broader than previously regarded.

Study of Hemoptysis in a Tertiary Care Center of Province 1: Causes and Recurrences

2020 ◽  
Vol 5 (2) ◽  
pp. 1050-1054
Author(s):  
Ram Hari Ghimire ◽  
Ashima Ghimire ◽  
Rupesh Kumar Shreewastav ◽  
Sushil Yadav ◽  
Bidesh Bidesh Bista
Keyword(s):  
Diagnostic Yield ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Number Of Patients ◽  
Chest Clinic ◽  
Telephone Calls

Introduction: Hemoptysis is a common but distressing and alarming symptom in a patient. Data related to detail clinical profile and follow up study of hemoptysis are lacking. Objective: This study was carried out to see the clinical profile of patients with hemoptysis and to study the recurrences in tertiary care centre of province 1 within the study period. Methodology: This was a prospective observational study conducted at the department of Pulmonary, Critical Care and Sleep Medicine of Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The study was carried out between 30th January 2017 to 1st February 2020. For follow up of recurrences of hemoptysis, the patients were asked for regular chest clinic follow up and regular telephone calls made to the patients, in case, patients could not attend the chest clinic for any reason. Results: A total of 150 patients were enrolled over the last 3 years. Among them 75% were male. The maximum number of patients (27%) were between 31-40 years of age group. Old sequelae of pulmonary tuberculosis (PTB) (32%) and bronchiectasis (28%) were the commonest cause of hemoptysis. Lung cancer (10%) and active PTB (10%) were other causes of hemoptysis. CT scan of the chest provided the highest (84%) diagnostic yield. Most of the cases were having mild hemoptysis (50%). 17% of the patients in our study had recurrences of hemoptysis. Conclusion: Old PTB sequelae with bronchiectasis (fibrobronchiectasis) were the commonest cause of hemoptysis. Conservative management worked most effectively in controlling hemoptysis, if used properly.

scholarly journals Clinical Profile and Outcome of Patients Presenting with Mushroom Poisoning in a Tertiary Care Center of Eastern Nepal

2013 ◽  
Vol 52 (192) ◽  
Author(s):  
Shatdal Chaudhary ◽  
Ramesh Kumar Chaurasia ◽  
Sushila Patel ◽  
Krishna Kumar Agrawal ◽  
Rakesh Aswani ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Acute Phase ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Rural Areas ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Mushroom Poisoning

Introduction: Accidental mushroom poisoning is constantly seen and regularly reported from all over world. Exact magnitude of problem and its clinical profile in Nepal is not well known. This study was done to evaluate clinical profile and treatment outcome of patients presenting with mushroom poisoning in the department of internal medicine, BPKIHS, Dharan. Methods: It is a prospective observational study conducted in department of internal medicine, BPKIHS, Dharan from 1st January 2008 to 31st December 2009. Informed consent was taken. All the patients were subjected to necessary laboratory investigation. They were followed up at 1 week and 1 month after discharge. Results: All together 60 patients were analyzed. Majority of subjects 56 (93.3%) were from rural areas. Vomiting and diarrhea were the two most common presentations seen in 56 (93.3%) subjects. The latent period for the symptoms were > 6 hours in 4 (6.7%) and < 6 hours in 56 (93.3%) subjects. Fulminant hepatic failure was seen in 6 (10%) subjects and among them 4 (66.7%) expired. After admission 3 (5%) subjects developed GI bleeding. Average duration of hospital stay was 4.6 days. In follow up recovery was complete in all subjects who survived the acute phase of poisoning. Conclusions: Especially in patients coming during rainy season mushroom poisoning should be considered in the differential diagnosis of acute gastroenteritis. Mortality is high in subjects with FHF whereas recovery is complete in subjects who survived the acute phase. Keywords: fulminant hepatic failure; gastroenteritis; mushroom poisoning; wild mushrooms.

scholarly journals COVID-19 outbreak in children with cancer in a tertiary care center of a developing country

2020 ◽  
Author(s):  
Abdul M ◽  
Prasanth Siri ◽  
Debasish Sahoo ◽  
Jagdish Meena ◽  
Aditya Gupta ◽  
...  
Keyword(s):  
Developing Country ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Children With Cancer

scholarly journals Clinical profile of retinoblastoma presenting in a tertiary care hospital, eastern Nepal

2017 ◽  
Vol 13 (3) ◽  
pp. 129-136
Author(s):  
Poonam Lavaju ◽  
BP Badhu ◽  
S Shah ◽  
SK Chaudhary ◽  
P Upadhyaya
Keyword(s):  
Optic Nerve ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Care Hospital ◽  
Duration Of Symptoms ◽  
Female Ratio ◽  
Mode Of Presentation ◽  
The Mean ◽  
Clinical Records

Background: Retinoblastoma is the commonest primary intraocular malignancy of childhood. Under-standing the different modes of presentation with timely intervention are associated with prognosis.Objective: To determine the clinical profile of retinoblastoma and its association with optic nerve infiltration by tumor.  Methods: A retrospective analysis of the clinical records and histopathological reports of patients admitted with retinoblastoma in a tertiary heath care center, eastern Nepal (June 2009 to July 2012) was carried out.Results: A total of 27 patients (28 eyes) with retinoblastoma were studied. The mean age at presentation was 2.89 ± 0.93 years. The mean duration of symptoms to presentation was 3.35 month, ranged from 7 days to 2 years. Male to female ratio was 3:2. Thirty-three percent patients were Muslims. Twentyseven patients (96.3%) had unilateral eye involvement. The commonest mode of presentation was leukocoria in 23 eyes (85.2%) followed by redness 9 eyes (33.3%), proptosis in 5 eyes (18.5%) and phthisis bulbi in one eye (3.7%). Histopathological reports of 26 eyes confirmed the diagnosis of retinoblastoma. One patient with distant metastases was referred to oncology center. Infiltration of the optic nerve by tumor cells was seen in five eyes (18.5%); of which two cases had proptosis (p-0.166). At two years follow up, recurrence was seen in one patient with proptosis and optic nerve infiltration (p-0.136). Age at presentation was positively associated with recurrence of tumor (p-0.005).Conclusion: Leucokoria was the most common mode of presentation of retinoblastoma. Larger sample size with longer follow up is required to come to a definite association with optic nerve infiltration by tumor. Health Renaissance 2015;13 (3): 129-136

Sign in / Sign up

Export Citation Format

Share Document