Amphiphilic block copolymer poly(lactic acid)-block -(glycidylazide polymer)-block -polystyrene: synthesis and self-assembly

2017 ◽  
Vol 66 (7) ◽  
pp. 1037-1043 ◽  
Author(s):  
Guoping Li ◽  
Haoxue Dong ◽  
Menghui Liu ◽  
Min Xia ◽  
Chunpeng Chai ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Block Copolymer ◽  
Self Assembly ◽  
Amphiphilic Block Copolymer ◽  
Poly Lactic Acid ◽  
Copolymer Poly ◽  
Polymer Block

Perfluorooctyl bromide traces self-assembled with polymeric nanovesicles for blood pool ultrasound imaging

2016 ◽  
Vol 4 (6) ◽  
pp. 979-988 ◽  
Author(s):  
Hao Li ◽  
Ping Wang ◽  
Xuan Wang ◽  
Tinghui Yin ◽  
Guofu Zhou ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Block Copolymer ◽  
Ethylene Oxide ◽  
Ultrasound Imaging ◽  
Self Assembly ◽  
Blood Pool ◽  
Perfluorooctyl Bromide ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Copolymer Poly

A novel perfluorooctyl bromide (PFOB)-loaded nanovesicle with a size of about 500 nm was prepared by self-assembly of an amphiphilic block copolymer, poly(ethylene oxide)-b-poly(d,l-lactic acid) (PEG-PDLLA), for blood pool ultrasound imaging.

The Self-Assembly of an Amphiphilic Block Copolymer: A Dissipative Particle Dynamics Study

2005 ◽  
Vol 42 (3) ◽  
pp. 180-183 ◽  
Author(s):  
S. G. Schulz ◽  
U. Frieske ◽  
H. Kuhn ◽  
G. Schmid ◽  
F. Müller ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Self Assembly ◽  
Dissipative Particle Dynamics ◽  
Particle Dynamics ◽  
The Self ◽  
Amphiphilic Block Copolymer

Polylactic acid block copolymer grafted temozolomide targeted nano delivery in the treatment of glioma

2021 ◽  
Vol 11 (5) ◽  
pp. 627-633
Author(s):  
Maokai Wang ◽  
Rongyan Kuang ◽  
Baoqing Huang ◽  
Defeng Ji
Keyword(s):  
Central Nervous System ◽  
Block Copolymer ◽  
Tumor Recurrence ◽  
Poly Lactic Acid ◽  
First Line ◽  
Kunitz Domain ◽  
The Central Nervous System ◽  
Modified Block ◽  
Copolymer Poly ◽  
Line Chemotherapy

Gliomas are tumors of the central nervous system; they can be invasive and are commonly treated by surgical resection, chemo, and radiotherapy. Removal of a glioma is dangerous and not always successful. Temozolomide (TMZ), the first-line chemotherapy drug for gliomas, inhibit tumor recurrence, and metastasis to some extent. TMZ is often accompanied by side effects such as anemia, fever, constipation, and more. Here using a double-targeted Kunitz domain Angiopep-2 (ANG) modified block copolymer poly(lactic acid)-polyethylene glycol (PEG-PLA) coated with TMZ, we constructed a nano-delivery system (ANG@PLA-PEG/TMZ) that crosses the blood-brain barrier (BBB) to treat gliomas.

Synthesis and solvent-dependent micellization of the amphiphilic block copolymer poly(styreneboronic acid)-block-polystyrene

2010 ◽  
Vol 48 (11) ◽  
pp. 2438-2445 ◽  
Author(s):  
Chengzhong Cui ◽  
Edward M. Bonder ◽  
Yang Qin ◽  
Frieder Jäkle
Keyword(s):  
Block Copolymer ◽  
Amphiphilic Block Copolymer ◽  
Copolymer Poly

Photo- and Thermo-Dual-Responsive Organic/Inorganic Hybrid Materials

2013 ◽  
Vol 538 ◽  
pp. 181-184 ◽  
Author(s):  
Xin De Tang ◽  
Ye Chen ◽  
Fa Qi Yu ◽  
Mei Shan Pei
Keyword(s):  
Block Copolymer ◽  
Hybrid Materials ◽  
Self Assembly ◽  
Polymeric Materials ◽  
Stimuli Responsive ◽  
Inorganic Hybrid ◽  
Dual Responsive ◽  
Hexyl Methacrylate ◽  
Poly Ethylene ◽  
Copolymer Poly

Organic/inorganic hybrid materials based upon stimuli-responsive copolymers have attracted an inceasing attention. Compared with the polymeric materials, these hybrid materials can form aggregates in aqueous solution with much more stable shape-persistance due to the inorganic structure, which facilitate the mass delivery and long-term life. A novel hybrid material based on a new reactive block copolymer, poly(ethylene oxide)-block-poly{3-(trimethoxysilyl)propyl methacrylate-co-N-isopropylacrylamide-co-6-[4-(4-methoxyphenylazo)phenoxy]hexyl methacrylate} [PEO-P(TMSPMA-NIPAM-AzoMA)] was synthesized via atom transfer radical polymerization (ATRP). The vesicles were obtained by self-assembly of the resulting block copolymer in a selective solvent, and then the PTMSPMA block was subjected to hydrolysis and polycondensation reaction to fix vesicle wall in the presence of triethylamine as a catalyst. The photo- and thermo- dual-responsive properties of the vesicles were investigated.

Self-assembly and disassembly of a redox-responsive ferrocene-containing amphiphilic block copolymer for controlled release

2015 ◽  
Vol 6 (10) ◽  
pp. 1817-1829 ◽  
Author(s):  
Lichao Liu ◽  
Leilei Rui ◽  
Yun Gao ◽  
Weian Zhang
Keyword(s):  
Controlled Release ◽  
Block Copolymer ◽  
Block Copolymers ◽  
Rhodamine B ◽  
Self Assembly ◽  
Amphiphilic Block Copolymer ◽  
Model Molecule ◽  
Redox Responsive

The synthesis and self-assembly of ferrocene-containing block copolymers PEG-b-PMAEFc, and the encapsulation and redox-responsive release of a model molecule (rhodamine B) upon external redox stimuli (H2O2).

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