Omega-3 fatty acids decrease prostate cancer progression associated with an anti-tumor immune response in eugonadal and castrated mice

The Prostate ◽  
2018 ◽  
Vol 79 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Nikunj Gevariya ◽  
Marjorie Besançon ◽  
Karine Robitaille ◽  
Valérie Picard ◽  
Lamoussa Diabaté ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Immune Response ◽  
Cancer Progression ◽  
Omega 3 Fatty Acids ◽  
Prostate Cancer Progression ◽  
Omega 3

scholarly journals Prostatic and Dietary Omega-3 Fatty Acids and Prostate Cancer Progression during Active Surveillance

2014 ◽  
Vol 7 (7) ◽  
pp. 766-776 ◽  
Author(s):  
Xavier Moreel ◽  
Janie Allaire ◽  
Caroline Léger ◽  
André Caron ◽  
Marie-Ève Labonté ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Active Surveillance ◽  
Cancer Progression ◽  
Omega 3 Fatty Acids ◽  
Prostate Cancer Progression ◽  
Omega 3

scholarly journals Effect of Dietary Omega-3 Fatty Acids on Tumor-Associated Macrophages and Prostate Cancer Progression

The Prostate ◽  
2016 ◽  
Vol 76 (14) ◽  
pp. 1293-1302 ◽  
Author(s):  
Pei Liang ◽  
Susanne M. Henning ◽  
Shiruyeh Schokrpur ◽  
Lily Wu ◽  
Ngan Doan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Cancer Progression ◽  
Omega 3 Fatty Acids ◽  
Prostate Cancer Progression ◽  
Omega 3 ◽  
Tumor Associated Macrophages

Omega-3 fatty acids effectively modulate growth performance, immune response, and disease resistance in fish against multiple stresses

Aquaculture ◽  
2021 ◽  
pp. 737506
Author(s):  
Neeraj Kumar ◽  
Nitish Kumar Chandan ◽  
Sanjay Kumar Gupta ◽  
Shashi Bhushan ◽  
Pooja Bapurao Patole
Keyword(s):  
Fatty Acids ◽  
Immune Response ◽  
Disease Resistance ◽  
Growth Performance ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Multiple Stresses

Dietary omega-3 fatty acids enhance the B1 but not the B2 cell immune response in mice with antigen-induced peritonitis

2014 ◽  
Vol 25 (2) ◽  
pp. 111-117 ◽  
Author(s):  
Valgerdur Tomasdottir ◽  
Sigrun Thorleifsdottir ◽  
Arnor Vikingsson ◽  
Ingibjorg Hardardottir ◽  
Jona Freysdottir
Keyword(s):  
Fatty Acids ◽  
Immune Response ◽  
Cell Immune Response ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals The Role of Micronutrients in Support of the Immune Response against Viral Infections

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3198 ◽  
Author(s):  
Francesco Pecora ◽  
Federica Persico ◽  
Alberto Argentiero ◽  
Cosimo Neglia ◽  
Susanna Esposito
Keyword(s):  
Fatty Acids ◽  
Immune Response ◽  
Immune System ◽  
Viral Infections ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Optimal Function ◽  
The Impact

Viral infections are a leading cause of morbidity and mortality worldwide, and the importance of public health practices including handwashing and vaccinations in reducing their spread is well established. Furthermore, it is well known that proper nutrition can help support optimal immune function, reducing the impact of infections. Several vitamins and trace elements play an important role in supporting the cells of the immune system, thus increasing the resistance to infections. Other nutrients, such as omega-3 fatty acids, help sustain optimal function of the immune system. The main aim of this manuscript is to discuss of the potential role of micronutrients supplementation in supporting immunity, particularly against respiratory virus infections. Literature analysis showed that in vitro and observational studies, and clinical trials, highlight the important role of vitamins A, C, and D, omega-3 fatty acids, and zinc in modulating the immune response. Supplementation with vitamins, omega 3 fatty acids and zinc appears to be a safe and low-cost way to support optimal function of the immune system, with the potential to reduce the risk and consequences of infection, including viral respiratory infections. Supplementation should be in addition to a healthy diet and fall within recommended upper safety limits set by scientific expert bodies. Therefore, implementing an optimal nutrition, with micronutrients and omega-3 fatty acids supplementation, might be a cost-effective, underestimated strategy to help reduce the burden of infectious diseases worldwide, including coronavirus disease 2019 (COVID-19).

scholarly journals Omega-3 Fatty Acids Survey in Men under Active Surveillance for Prostate Cancer: from Intake to Prostate Tissue Level

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1616 ◽  
Author(s):  
Hanane Moussa ◽  
Molière Nguile-Makao ◽  
Karine Robitaille ◽  
Marie-Hélène Guertin ◽  
Janie Allaire ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Active Surveillance ◽  
Experimental Studies ◽  
Low Risk ◽  
Prostate Tissue ◽  
High Grade ◽  
Protective Effects ◽  
Omega 3 Fatty Acids ◽  
Omega 3

Dietary omega-3 fatty acids (ω3), particularly long-chain ω3 (LCω3), have protective effects against prostate cancer (PCa) in experimental studies. Observational studies are conflicting, possibly because of the biomarker used. This study aimed at evaluating associations between grade reclassification and ω3 levels assessed in prostatic tissue, red blood cells (RBC), and diet. We conducted a validation cross-sectional study nested within a phase II clinical trial. We identified 157 men diagnosed with low-risk PCa who underwent a first active surveillance repeat prostate biopsy session. Fatty acid (FA) intake was assessed using a food frequency questionnaire and their levels measured in prostate tissue and RBC. Associations were evaluated using logistic regression. At first repeat biopsy session, 39 (25%) men had high-grade PCa (grade group ≥2). We found that high LCω3-eicosapentaenoic acid (EPA) level in prostate tissue (odds ratio (OR) 0.25; 95% (confidence interval (CI) 0.08–0.79; p-trend = 0.03) was associated with lower odds of high-grade PCa. Similar results were observed for LCω3 dietary intake (OR 0.30; 95% CI 0.11-0.83; p-trend = 0.02) but no association for RBC. LCω3-EPA levels in the target prostate tissue are inversely associated with high-grade PCa in men with low-risk PCa, supporting that prostate tissue FA, but not RBC FA, is a reliable biomarker of PCa risk.

scholarly journals Omega-3 Fatty Acids and Other FFA4 Agonists Inhibit Growth Factor Signaling in Human Prostate Cancer Cells

2014 ◽  
Vol 352 (2) ◽  
pp. 380-394 ◽  
Author(s):  
Ze Liu ◽  
Mandi M. Hopkins ◽  
Zhihong Zhang ◽  
Chrystal B. Quisenberry ◽  
Louise C. Fix ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fatty Acids ◽  
Growth Factor ◽  
Cancer Cells ◽  
Human Prostate ◽  
Growth Factor Signaling ◽  
Human Prostate Cancer ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Prostate Cancer Cells
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