Medicinal plants and bioactive natural products as inhibitors of NLRP3 inflammasome

2021 ◽  
Author(s):  
Mohammad Bagherniya ◽  
Hamed Khedmatgozar ◽  
Omid Fakheran ◽  
Suowen Xu ◽  
Thomas P. Johnston ◽  
...  
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Nlrp3 Inflammasome ◽  
Bioactive Natural Products

Search for bioactive natural products from medicinal plants of Bangladesh

2010 ◽  
Vol 64 (4) ◽  
pp. 393-401 ◽  
Author(s):  
Firoj Ahmed ◽  
Samir Kumar Sadhu ◽  
Masami Ishibashi
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Bioactive Natural Products

Recent investigations of bioactive natural products from endophytic, marine-derived, insect pathogenic fungi and Thai medicinal plants

2014 ◽  
Vol 86 (6) ◽  
pp. 979-993 ◽  
Author(s):  
Chulabhorn Mahidol ◽  
Prasat Kittakoop ◽  
Vilailak Prachyawarakorn ◽  
Phanruethai Pailee ◽  
Hunsa Prawat ◽  
...  
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Biological Activities ◽  
Geographical Location ◽  
Pathogenic Fungi ◽  
Biologically Active ◽  
Bioactive Substances ◽  
Bioactive Natural Products ◽  
Insect Pathogenic Fungi ◽  
Living Organisms

AbstractLiving organisms in Thailand are very diverse due to the unique geographical location of Thailand. The diversity of Thai bioresources has proven to be a rich source of biologically active compounds. The present review covers bioactive substances from Thai endophytic, marine-derived, insect pathogenic fungi and medicinal plants. Many new compounds isolated from Thai bioresources have diverse skeletons belonging to various classes of natural products. These compounds exhibited an array of biological activities, and some are of pharmaceutical interest. Bioactive compounds from Thai bioresources have not only attracted organic chemists to develop strategies for total synthesis, but also attracted (chemical) biologists to investigate the mechanisms of action. The chemistry and biology of some selected compounds are also discussed in this review.

scholarly journals Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action

2021 ◽  
Vol 11 (21) ◽  
pp. 10220
Author(s):  
Hari Prasad Devkota
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Human Health ◽  
Molecular Mechanisms ◽  
Mechanisms Of Action ◽  
Traditional Medicines ◽  
Bioactive Natural Products ◽  
Ancient Times

Medicinal plants have been used for the maintenance of human health since ancient times in the form of food, spices, and traditional medicines [...]

Artemia species: An Important Tool to Screen General Toxicity Samples

2020 ◽  
Vol 26 (24) ◽  
pp. 2892-2908 ◽  
Author(s):  
Epole Ntungwe N ◽  
Eva M. Domínguez-Martín ◽  
Amilcar Roberto ◽  
Joana Tavares ◽  
Vera M. S. Isca ◽  
...  
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Brine Shrimp ◽  
Low Cost ◽  
Artemia Salina ◽  
Toxicity Assay ◽  
Brine Shrimp Lethality ◽  
Bioactive Natural Products ◽  
Therapeutic Drugs ◽  
Brine Shrimp Lethality Assay

Medicinal plants are a good source of novel therapeutic drugs, due to the phytochemicals present. Artemia, commonly known as brine shrimp, is a tiny halophilic invertebrate belonging to class Crustacean, which plays an important role in saline aquatic and marine eco-systems. Besides its usage in aquaculture, it is also highly valued for its application in toxicity detection and it is used in areas such as Ecology, Physiology, Ecotoxicology, Aquaculture and Genetics. Furthermore, Artemia based lethality assay (brine shrimp lethality assay, BSLA) is rapid, convenient and low cost. Presently, brine shrimp lethality assays are enormously employed in research and applied toxicology. It has been used in the study of natural products as a preliminary toxicity assay to screen a large number of extracts and compounds for drug discovery in medicinal plants. The aim of this review paper is to collect, organize, select and discuss the existing knowledge about the different uses of Artemia salina as a bench-top bioassay for the discovery and purification of bioactive natural products.

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