An Update on Bioactive Natural Products from Endophytic Fungi of Medicinal Plants

2019 ◽  
pp. 121-153 ◽  
Author(s):  
Nisha Sharma ◽  
Vishal Sharma ◽  
Vidushi Abrol ◽  
Anil Panghal ◽  
Sundeep Jaglan
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Endophytic Fungi ◽  
Bioactive Natural Products

Bioactive Natural Products of Endophytic Fungi from Marine Algae

Marine OMICS ◽  
2016 ◽  
pp. 383-405
Author(s):  
Vasuki Subramanian ◽  
P. Anantharaman ◽  
K. Kathiresan
Keyword(s):  
Natural Products ◽  
Endophytic Fungi ◽  
Marine Algae ◽  
Bioactive Natural Products

scholarly journals New and bioactive natural products from an endophyte of Panax notoginseng

RSC Advances ◽  
2017 ◽  
Vol 7 (60) ◽  
pp. 38100-38109 ◽  
Author(s):  
Jun Xie ◽  
Ying-Ying Wu ◽  
Tian-Yuan Zhang ◽  
Meng-Yue Zhang ◽  
Wei-Wei Zhu ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Natural Products ◽  
Secondary Metabolites ◽  
Antiviral Activity ◽  
Cytotoxic Activity ◽  
Endophytic Fungi ◽  
Panax Notoginseng ◽  
Bioactive Natural Products

Secondary metabolites with cytotoxic activity, antiviral activity and antimicrobial activity from the endophytic fungi of Panax notoginseng.

Endophytic fungi found in association with Smallanthus sonchifolius (Asteraceae) as resourceful producers of cytotoxic bioactive natural products

2008 ◽  
Vol 49 (2) ◽  
pp. 142-151 ◽  
Author(s):  
Margareth B. C. Gallo ◽  
Fernanda O. Chagas ◽  
Marília O. Almeida ◽  
Cláudia C. Macedo ◽  
Bruno C. Cavalcanti ◽  
...  
Keyword(s):  
Natural Products ◽  
Endophytic Fungi ◽  
Bioactive Natural Products ◽  
Smallanthus Sonchifolius

Search for bioactive natural products from medicinal plants of Bangladesh

2010 ◽  
Vol 64 (4) ◽  
pp. 393-401 ◽  
Author(s):  
Firoj Ahmed ◽  
Samir Kumar Sadhu ◽  
Masami Ishibashi
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Bioactive Natural Products

scholarly journals Endophytes of Brazilian Medicinal Plants With Activity Against Phytopathogens

2021 ◽  
Vol 12 ◽  
Author(s):  
Jucélia Iantas ◽  
Daiani Cristina Savi ◽  
Renata da Silva Schibelbein ◽  
Sandriele Aparecida Noriler ◽  
Beatriz Marques Assad ◽  
...  
Keyword(s):  
New Species ◽  
Medicinal Plants ◽  
Endophytic Fungi ◽  
Dna Sequences ◽  
Mycelial Growth ◽  
High Performance ◽  
Biological Activities ◽  
Phytopathogenic Fungi ◽  
Plant Diseases ◽  
Bioactive Natural Products

Plant diseases caused by phytopathogens are responsible for significant crop losses worldwide. Resistance induction and biological control have been exploited in agriculture due to their enormous potential. In this study, we investigated the antimicrobial potential of endophytic fungi of leaves and petioles of medicinal plants Vochysia divergens and Stryphnodendron adstringens located in two regions of high diversity in Brazil, Pantanal, and Cerrado, respectively. We recovered 1,304 fungal isolates and based on the characteristics of the culture, were assigned to 159 phenotypes. One isolate was selected as representative of each phenotype and studied for antimicrobial activity against phytopathogens. Isolates with better biological activities were identified based on DNA sequences and phylogenetic analyzes. Among the 159 representative isolates, extracts from 12 endophytes that inhibited the mycelial growth (IG) of Colletotrichum abscissum (≥40%) were selected to expand the antimicrobial analysis. The minimum inhibitory concentrations (MIC) of the extracts were determined against citrus pathogens, C. abscissum, Phyllosticta citricarpa and Xanthomonas citri subsp. citri and the maize pathogen Fusarium graminearum. The highest activity against C. abscissum were from extracts of Pseudofusicoccum stromaticum CMRP4328 (IG: 83% and MIC: 40 μg/mL) and Diaporthe vochysiae CMRP4322 (IG: 75% and MIC: 1 μg/mL), both extracts also inhibited the development of post-bloom fruit drop symptoms in citrus flowers. The extracts were promising in inhibiting the mycelial growth of P. citricarpa and reducing the production of pycnidia in citrus leaves. Among the isolates that showed activity, the genus Diaporthe was the most common, including the new species D. cerradensis described in this study. In addition, high performance liquid chromatography, UV detection, and mass spectrometry and thin layer chromatography analyzes of extracts produced by endophytes that showed high activity, indicated D. vochysiae CMRP4322 and P. stromaticum CMRP4328 as promising strains that produce new bioactive natural products. We report here the capacity of endophytic fungi of medicinal plants to produce secondary metabolites with biological activities against phytopathogenic fungi and bacteria. The description of the new species D. cerradensis, reinforces the ability of medicinal plants found in Brazil to host a diverse group of fungi with biotechnological potential.

Recent investigations of bioactive natural products from endophytic, marine-derived, insect pathogenic fungi and Thai medicinal plants

2014 ◽  
Vol 86 (6) ◽  
pp. 979-993 ◽  
Author(s):  
Chulabhorn Mahidol ◽  
Prasat Kittakoop ◽  
Vilailak Prachyawarakorn ◽  
Phanruethai Pailee ◽  
Hunsa Prawat ◽  
...  
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Biological Activities ◽  
Geographical Location ◽  
Pathogenic Fungi ◽  
Biologically Active ◽  
Bioactive Substances ◽  
Bioactive Natural Products ◽  
Insect Pathogenic Fungi ◽  
Living Organisms

AbstractLiving organisms in Thailand are very diverse due to the unique geographical location of Thailand. The diversity of Thai bioresources has proven to be a rich source of biologically active compounds. The present review covers bioactive substances from Thai endophytic, marine-derived, insect pathogenic fungi and medicinal plants. Many new compounds isolated from Thai bioresources have diverse skeletons belonging to various classes of natural products. These compounds exhibited an array of biological activities, and some are of pharmaceutical interest. Bioactive compounds from Thai bioresources have not only attracted organic chemists to develop strategies for total synthesis, but also attracted (chemical) biologists to investigate the mechanisms of action. The chemistry and biology of some selected compounds are also discussed in this review.

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