Determination of the number of observers needed to evaluate a subjective test and its application in two PD‐L1 studies

2021 ◽  
Author(s):  
Gang Han ◽  
Michael J. Schell ◽  
Emily S. Reisenbichler ◽  
Bohong Guo ◽  
David L. Rimm
Keyword(s):  
2021 ◽  
Vol 74 (6) ◽  
pp. 1433-1438
Author(s):  
Helfira M. Kuz ◽  
Oleksandra I. Teslenko ◽  
Liubov B. Yerys ◽  
Hennadii M. Balia ◽  
Vitalii S. Kuz

The aim: The work is devoted to studying the results of treatment of edentulous patients with dentures, made of thermoplastic material “Vertex ThermoSense”. Materials and methods: The non-acrylic thermoplastic plastic “Vertex ThermoSense” was used in our research work. The quality evaluation was carried out with the help of an objective-subjective test “BOFSAS”, determination of biopotentials of masticatory muscles with the help of electromyography and determination of masticatory efficiency according to I.S. Rubinov. Results: It can be noted that the use of the basic thermoplastic material “Vertex ThermoSense” allows to achieve better fixation and stabilization of complete removable prostheses. It is subjectively confirmed by the “BOFSAS” test, objectively - by data of electromyographic studies and time the masticatory test of I.S. Rubinov. Conclusion: We can conclude that adaptation to dentures, made of the basic thermoplastic material “Vertex ThermoSense”, goes in short terms and it is almost painless, based on the results of our studies. KEY WORDS: “Vertex ThermoSense”, thermoplastic dental materials, complete absence of teeth, electromyography Wiad Lek. 2021;74(6):-


2013 ◽  
Vol 471 ◽  
pp. 64-68 ◽  
Author(s):  
Paulraj Paulraj ◽  
Allan Andrew Melvin ◽  
Yaacob Sazali

Determination of vehicle comfort is important because continuous exposure to the noise and vibration leads to health problems for the driver and passengers. In this paper, a vehicle comfort level classification system has been proposed to detect the comfort level in cars using artificial neural network. A database consisting of sound samples obtained from 30 local cars is used. In the stationary condition, the sound pressure level is measured at 1300 RPM, 2000 RPM and 3000 RPM. In the moving condition, the sound is recorded while the car is moving at 30 km/h up to 110 km/h. Subjective test is conducted to find the Jurys evaluation for the specific sound sample. The correlation between the subjective and the objective evaluation is also tested. The relationship between the subjective results and the sound metrics is modelled using Probabilistic Neural Network. It is found from the research that the Temporal Composite Feature gives better classification accuracy for both stationary and moving condition model, 89.51% and 85.61% respectively.


2021 ◽  
pp. 002201832110351
Author(s):  
Michael Bohlander

The debate about the two-pronged Ghosh test for dishonesty has troubled academics and practitioners alike for some time. Concerns were raised about the jury’s ability to determine both the objective honesty standards and the defendant’s personal compliance with it, which might result in non-meritorious personal views allowing her to escape a dishonesty verdict. In Ivey, followed by Barton and Booth, the subjective test was abandoned altogether. The change has brought no doctrinal improvement, but instead unacceptably broadened criminal liability. Leaving the determination of a nebulous moral concept such as dishonesty to the jury is misguided, as it means determining a normative rule in the first place, which is not the jury’s role. Looking at the German law on theft and fraud as a comparator system, the paper argues that dishonesty should be abandoned and replaced by a lawfulness element to which the rules on mistake of civil law can then be applied.


2018 ◽  
pp. 11-19
Author(s):  
V.S. Kuz ◽  
V.N. Dvornyk ◽  
G.M. Kuz` ◽  
G.N. Balia ◽  
I.N. Martinenko

One of the most important criteria of assessing of the quality manufactured prostheses and the functional state of dentoalveolar system is restoration of the degree of chewing efficiency. Chewing efficiency is determined by the help of classical methods, and by the help of modern technologies and mostly depends on the quality of the manufactured structures. The production of qualitative complete removable prostheses is dependent on the properties of the basic material. The main group of materials for the manufacturing of such structures is acrylic plastics of hot polymerization. Orthopedists often use thermoplastic plastics for manufacturing of complete removable prostheses nowadays. These basic materials allow avoiding the disadvantages of acrylic base plastics, and improving the functional qualities of removable dentures. Aim. The work is concerned with study in the clinic of orthopedic dentistry the results of treatment of patients with complete absence of teeth with prostheses made of thermoplastic material «Deflex Acrylato», using various functional tests. Materials and methods. During all the work, the thermoplastic plastic «Deflex Acrylato» was used. The quality evaluation of all our designs was carried out with the help of an objective – subjective test «BOFSAC», determination of biopotentials of masticatory muscles with the help of electromyography and determination of masticatory efficiency according to I.S. Rubinov. Results. As a result of our work, it can be determined that the use of the basic thermoplastic material «Deflex Acrylato» allows achieving better fixation and stabilization of complete removable prostheses, which is subjectively confirmed by the «BOFSAC» test, objectively – data of electromyographic studies and time indices of the masticatory test by I.S. Rubinov. Conclusions. Based on the results of our studies, one can conclude that adaptation to prosthesis made from the basic thermoplastic material «Deflex Acrylato» is short-timed and almost painless.


1966 ◽  
Vol 25 ◽  
pp. 93-97
Author(s):  
Richard Woolley

It is now possible to determine proper motions of high-velocity objects in such a way as to obtain with some accuracy the velocity vector relevant to the Sun. If a potential field of the Galaxy is assumed, one can compute an actual orbit. A determination of the velocity of the globular clusterωCentauri has recently been completed at Greenwich, and it is found that the orbit is strongly retrograde in the Galaxy. Similar calculations may be made, though with less certainty, in the case of RR Lyrae variable stars.


1999 ◽  
Vol 190 ◽  
pp. 549-554
Author(s):  
Nino Panagia

Using the new reductions of the IUE light curves by Sonneborn et al. (1997) and an extensive set of HST images of SN 1987A we have repeated and improved Panagia et al. (1991) analysis to obtain a better determination of the distance to the supernova. In this way we have derived an absolute size of the ringRabs= (6.23 ± 0.08) x 1017cm and an angular sizeR″ = 808 ± 17 mas, which give a distance to the supernovad(SN1987A) = 51.4 ± 1.2 kpc and a distance modulusm–M(SN1987A) = 18.55 ± 0.05. Allowing for a displacement of SN 1987A position relative to the LMC center, the distance to the barycenter of the Large Magellanic Cloud is also estimated to bed(LMC) = 52.0±1.3 kpc, which corresponds to a distance modulus ofm–M(LMC) = 18.58±0.05.


1961 ◽  
Vol 13 ◽  
pp. 29-41
Author(s):  
Wm. Markowitz
Keyword(s):  

A symposium on the future of the International Latitude Service (I. L. S.) is to be held in Helsinki in July 1960. My report for the symposium consists of two parts. Part I, denoded (Mk I) was published [1] earlier in 1960 under the title “Latitude and Longitude, and the Secular Motion of the Pole”. Part II is the present paper, denoded (Mk II).


1972 ◽  
Vol 1 ◽  
pp. 27-38
Author(s):  
J. Hers

In South Africa the modern outlook towards time may be said to have started in 1948. Both the two major observatories, The Royal Observatory in Cape Town and the Union Observatory (now known as the Republic Observatory) in Johannesburg had, of course, been involved in the astronomical determination of time almost from their inception, and the Johannesburg Observatory has been responsible for the official time of South Africa since 1908. However the pendulum clocks then in use could not be relied on to provide an accuracy better than about 1/10 second, which was of the same order as that of the astronomical observations. It is doubtful if much use was made of even this limited accuracy outside the two observatories, and although there may – occasionally have been a demand for more accurate time, it was certainly not voiced.


2000 ◽  
Vol 179 ◽  
pp. 205-208
Author(s):  
Pavel Ambrož ◽  
Alfred Schroll

AbstractPrecise measurements of heliographic position of solar filaments were used for determination of the proper motion of solar filaments on the time-scale of days. The filaments have a tendency to make a shaking or waving of the external structure and to make a general movement of whole filament body, coinciding with the transport of the magnetic flux in the photosphere. The velocity scatter of individual measured points is about one order higher than the accuracy of measurements.


1975 ◽  
Vol 26 ◽  
pp. 341-380 ◽  
Author(s):  
R. J. Anderle ◽  
M. C. Tanenbaum

AbstractObservations of artificial earth satellites provide a means of establishing an.origin, orientation, scale and control points for a coordinate system. Neither existing data nor future data are likely to provide significant information on the .001 angle between the axis of angular momentum and axis of rotation. Existing data have provided data to about .01 accuracy on the pole position and to possibly a meter on the origin of the system and for control points. The longitude origin is essentially arbitrary. While these accuracies permit acquisition of useful data on tides and polar motion through dynamio analyses, they are inadequate for determination of crustal motion or significant improvement in polar motion. The limitations arise from gravity, drag and radiation forces on the satellites as well as from instrument errors. Improvements in laser equipment and the launch of the dense LAGEOS satellite in an orbit high enough to suppress significant gravity and drag errors will permit determination of crustal motion and more accurate, higher frequency, polar motion. However, the reference frame for the results is likely to be an average reference frame defined by the observing stations, resulting in significant corrections to be determined for effects of changes in station configuration and data losses.


Sign in / Sign up

Export Citation Format

Share Document