scholarly journals VP50.10: Predicting fetal and maternal complications with sFlt1/PlGF ratio in hypertensive disorders of pregnancy

2020 ◽  
Vol 56 (S1) ◽  
pp. 287-287
Author(s):  
D. Di Martino ◽  
V. Sterpi ◽  
M. Parasiliti ◽  
A. Caricati ◽  
V. Barbati ◽  
...  
Keyword(s):  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Hypertensive Disorders ◽  
Plgf Ratio

scholarly journals Study of liver function tests in hypertensive disorders of pregnancy

2018 ◽  
Vol 7 (3) ◽  
pp. 1212
Author(s):  
Radhika Pusuloori ◽  
K. Dilzith Arora
Keyword(s):  
Prospective Study ◽  
Pregnant Women ◽  
Liver Function Tests ◽  
Risk Category ◽  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Hypertensive Disorders ◽  
Maternal Morbidity And Mortality ◽  
Set Up ◽  
A Prospective Study

Background: Hypertensive disorders of pregnancy with spectrum complications is one among leading causes of feto-maternal morbidity and mortality especially when its associated with HELLP syndrome.Methods: The present prospective study was conducted over a period of three years in the department of obstetrics and gynecology at Chalmeda Anandarao Institute of Medical Sciences, Karimnagar, Telangana from January 2008 to January 2009. This is a prospective study on 50 pregnant women with 28-40 weeks of gestation with diastolic BP ≥110 mm Hg recorded 6 hours apart.Results: This is a prospective study on 50 pregnant women with 28-40 weeks of gestation with diastolic BP≥110 mm Hg recorded 6 hours apart. Severe pre eclampsia was seen in younger age group ˂25 years. In patients with raised LFTs unbooked cases were more (64%) showing complications are more in unbooked cases. Renal complications are seen in 16% of the total cases and in 28% of the cases with raised LFTs. In overall study group number of primi gravid were 50% and multi were 27%. Incidence of severe pre eclampsia was 78% in overall cases. In patients with raised LFTs the incidence was 30 (88%).Conclusions: Detection of increased LFTs in cases of severe pre-eclampsia is a risk category, associated with increased rate of feto-maternal complications, compared to severe pre-eclampsia with normal LFTs. Such cases need special attention with early detection and referral to higher centre with better facilities of NICU set up to reduce the complications and mortality.

Are maternal complications predictable at admission for early preterm hypertensive disorders of pregnancy?

2004 ◽  
Vol 191 (6) ◽  
pp. S38
Author(s):  
Annelies Rep ◽  
Wessel Ganzevoort ◽  
Hanneke de Vries ◽  
Gouke Bonsel ◽  
Hans Wolf
Keyword(s):  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Hypertensive Disorders

scholarly journals sFlt-1/plgf ratio in hypertensive disorders of pregnancy in patients affected by covid-19

2021 ◽  
Author(s):  
Chiara Maria Soldavini ◽  
Daniela Di Martino ◽  
Elisa Sabattini ◽  
Sara Ornaghi ◽  
Vittoria Sterpi ◽  
...  
Keyword(s):  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Plgf Ratio

scholarly journals The predictive value of sFlt-1/PIGF ratio in high risk patients for the development of preeclampsia

2019 ◽  
Vol 8 (9) ◽  
pp. 3705
Author(s):  
Isha Sunil ◽  
Mitali Sharma
Keyword(s):  
Positive Predictive Value ◽  
Negative Predictive Value ◽  
Predictive Value ◽  
Maternal Morbidity ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Maternal Morbidity And Mortality ◽  
Risk Patients ◽  
The Mean ◽  
Plgf Ratio

Background: Hypertensive disorders of pregnancy constitute a major cause of maternal morbidity and mortality. Pre-eclampsia/eclampsia ranks second only to haemorrhage as a specific, direct cause of maternal mortality. A number of markers have been under study for the early detection of this disease. The study aims to evaluate the predictive value of sFlt-1/PlGF ratio for preeclampsia.Methods: This study was conducted in the Department of Gynaecology and Obstetrics of ASCOMS hospital, Jammu for a period of 6 months from Jan 2019 to June 2019. 50 antenatal patients attending the outpatient department with risk factors for developing preeclampsia were enrolled in the study. Their sFlT-1/PIGF ratio was determined at gestational age of 20 weeks to 37 weeks and its predictive value was evaluated.Results: In the present study, 8 patients developed preeclampsia subsequently. The mean sFlt-1/PIGF ratio values were significantly higher in the patients who developed preeclampsia (73.5) than who did not develop the disease (26.07). The positive predictive value at 1 week was 41.66% and negative predictive value was 100%. At 4 weeks, positive predictive value was 66.66% and negative predictive value was 100%.Conclusions: The present study suggests sFlt-1/PIGF ratio values are useful marker was a predictor of preeclampsia and values >38 were associated with preeclampsia. It is more useful in ruling out preeclampsia than ruling in the disease.

scholarly journals Prevalence of hypertensive disorders of pregnancy and its maternal outcome in a tertiary care hospital, Salem, Tamil Nadu, India

2019 ◽  
Vol 9 (1) ◽  
pp. 236
Author(s):  
Subha Sivagami Sengodan ◽  
Sreeprathi N.
Keyword(s):  
Tamil Nadu ◽  
Gestational Hypertension ◽  
Tertiary Care ◽  
Chronic Hypertension ◽  
Hypertensive Disorder ◽  
Care Hospital ◽  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Hypertensive Disorders ◽  
Obstetrics And Gynaecology

Background: Hypertensive disorders complicate 5-10% of all pregnancies and together forms the deadly triad- along with hemorrhage and heart disease that contributes greatly to maternal morbidity and mortality. Objective of this study was to determine the prevalence of hypertensive disorders of pregnancy and its maternal complications in patients attending obstetrics and gynaecology department, Government Mohan Kumaramangalam Medical College Hospital, Salem.Methods: This is a prospective study conducted from August 2018 to July 2019 in the department of obstetrics and gynaecology. Patients diagnosed with hypertensive disorders of pregnancy was evaluated and data were collected.Results: A total of 19,383 pregnant women visited obstetrics and gynaecology department over a period of one year, out of which 2028 were diagnosed with hypertensive disorders of pregnancy. Hence the prevalence of hypertensive disorders in pregnancy is 10.4%. Among 2028 hypertensive disorder cases, Gestational hypertension were 962 cases (47.4%), pre-eclampsia 661 cases (32.6%), chronic hypertension 166 cases (8.2%) and pre-eclampsia superimposed on chronic hypertension 239 cases (11.8%). The prevalence was highest among primigravida (54%) compared to multigravida (46%). Hypertensive disorders were highest among the age group of 18-22 years in our study. Most common maternal complication in our study was HELLP syndrome.Conclusions: Prevalence of hypertensive disorders was high in our study. Early detection and timely intervention decrease the maternal complications.

Multiple pregnancy

2020 ◽  
pp. 253-267
Author(s):  
Surabhi Nanda ◽  
James P. Neilson
Keyword(s):  
Preterm Birth ◽  
Multiple Pregnancy ◽  
Multiple Pregnancies ◽  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Singleton Pregnancy ◽  
Birth Complications ◽  
Hypertensive Disorders ◽  
Increased Risk ◽  
Need Support

There has been a consistent rise in multiple pregnancies over recent years. Such pregnancies are at increased risk of miscarriage, fetal abnormalities, preterm birth, complications specific to shared placentation including twin-to-twin transfusion syndrome, selective growth restriction, and twin anaemia–polycythaemia sequence. In addition, a woman with a multiple pregnancy is at a higher risk of maternal complications including pre-eclampsia and other hypertensive disorders of pregnancy, obstetric cholestasis, gestational diabetes, exaggerated maternal pregnancy symptoms, and postpartum haemorrhage. Antenatal care in a multiple pregnancy should ideally be offered in a dedicated setting, with increased contact with the healthcare professionals compared to a singleton pregnancy. Such pregnancies, especially when complicated, need support and appropriate counselling to prepare for an optimal outcome.

scholarly journals Outcome of Hypertensive Disorders of Pregnancy

2014 ◽  
Vol 3 (1) ◽  
pp. 46-52
Author(s):  
Akhter Zahan ◽  
Md Nazrul Islam ◽  
Netay Kumer Sharma ◽  
Khadiza Begum ◽  
Kinkon Rani Bhowmik
Keyword(s):  
Birth Weight ◽  
Severe Preeclampsia ◽  
Neonatal Outcomes ◽  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Cross Sectional ◽  
Hypertensive Disorders ◽  
Mild Preeclampsia ◽  
Adverse Pregnancy ◽  
The Impact

Hypertension is the most common medical problem encountered in pregnancy and are leading causes of maternal, fetal and neonatal morbidity and mortality worldwide. Definitions, classifications, assessment and management of hypertensive disorders vary considerably in the literature and from country to country. In light of this, we aimed to evaluate different types of hypertensive disorders of pregnancy and to determine the impact of hypertensive disorders of pregnancy (HDP) on maternal, fetal and neonatal outcomes. This Cross Sectional descriptive study was conducted in the Department of Gynaecology and Obstetrics of Community Based Medical College, Mymensingh, Bangladesh from April 2012 to March 2013. All the patients who were diagnosed with HDP and gestational age of 20-40 weeks during the study period were included in the study. Patients with preexisting renal disease, diabetes mellitus, active urinary tract infection or who refused to cooperate with the study were excluded. The data regarding demographic variables, clinical features, pregnancy characteristics, maternal complications, fetal and neonatal outcomes were gathered from available data on medical record files. Edema was the most common clinical symptom. Primipara mothers were predominant in the both mild and severe preeclampsia group. Majority (88%) of mothers in mild preeclampsia group had a history of spontaneous vaginal birth, however 82.9% in severe preeclampsia group by Lower Segment Caesarean Section (LSCS). A higher proportion of mother in mild preeclampsia group delivered at term, whereas 65.7% in severe preeclampsia group delivered preterm. The proportion of maternal complications such as were significantly higher in severe preeclampsia group than those in mild preeclampsia group. Most babies (92%) were born with a birth weight 2500 grams in mild preeclampsia group, while 70% born with birth weight between 1500 - 2499 grams in severe preeclampsia group. All the babies were born with apgar score less than 7 between mild and severe preeclampsia groups. About three quarter (74.3%) of neonates born to women the severe preeclampsia group required resuscitation compared to 40% in mild preeclampsia group. The maternal death, still birth and neonatal death were found higher in severe preeclampsia group than those in mild preeclampsia group. Pregnancies affected by hypertensive disorders require careful monitoring due to the increased risks of adverse pregnancy outcomes. Frequency of severe hypertensive disorders is high in our set up. It is associated with high maternal, fetal and neonatal mortality CBMJ 2014 January: Vol. 03 No. 01 P: 46-52

scholarly journals Twin pregnancies: a retrospective analysis

2021 ◽  
Vol 10 (5) ◽  
pp. 1828
Author(s):  
Tushar S. Zanjade ◽  
Madhurya Bezbaruah ◽  
Seema Rai ◽  
Jitendra D. Mane
Keyword(s):  
Preterm Delivery ◽  
Favourable Outcome ◽  
In Vitro Fertilisation ◽  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Hypertensive Disorders ◽  
Tertiary Teaching ◽  
Labour Room ◽  
Twin Pregnancies

Background: This study aims to analyse the maternal and neonatal complications in twin pregnancy at tertiary institute.Methods: This was a retrospective study of multiple pregnancies after 26 weeks gestation at a tertiary teaching hospital between January 2020 to December 2020. Maternal and neonatal data was collected from the labour room delivery register and NICU records.Results: Out of 1212 births during this period, 66 were twin pregnancies with an incidence of 5.54%. Most of women had twinning after in vitro fertilisation (IVF) treatment (77.27%). Thirty-seven (56.06%) women were in the age group of 21-30 years and primigravida contributed to 63.63% of all twin pregnancies. Maternal complications most frequently noticed was hypertensive disorders of pregnancy in 27 (40.90%) women, Gestational diabetes mellitus (GDM) in 24 (36.36%) women, preterm rupture of membranes (PROM)/ preterm premature rupture of membranes (PPROM) in 21 (31.18%) women, Intrahepatic cholestasis of pregnancy (IHCP) in 4 (6.06%) women, hypothyroidism in 12 (18.8.1%) women and antepartum hemorrhage (APH) in 4 (6.06%). Caesarean section was performed on 49 (74.25%) women with abnormal presentation as indication in 18 (36.73%). 80.30% women had preterm delivery with 86 (65.15 %) neonates having NICU admission. There was no maternal mortality and 1 (1,16 %) perinatal mortality in NICU admitted neonates.Conclusions: This study reveals with increasing ART treatment the incidence of twin pregnancies is increasing along with its maternal complications like hypertensive disorders of pregnancy, GDM and preterm delivery. Frequent antenatal care for early detection of complications, multi-disciplinary approach is key for favourable outcome. 

scholarly journals Evaluation of Pregnancy Outcomes in Women with Hypertension Disorders of Pregnancy

2021 ◽  
Vol 15 (10) ◽  
pp. 3420-3422
Author(s):  
Kalsoom Essa Bhattani ◽  
Shumaila Khawaja Khail ◽  
Kashif Ali Samin ◽  
Zubaida Khanum Wazir ◽  
Mobashara Ghulam Muhammad ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Pregnant Women ◽  
Gestational Age ◽  
Pregnancy Outcomes ◽  
Postpartum Hemorrhage ◽  
Health Centre ◽  
Mode Of Delivery ◽  
Hypertensive Disorders Of Pregnancy ◽  
Maternal Complications ◽  
Hypertensive Disorders

Background and Aim: Globally, hypertension disorder is the most common disorder in pregnancy. It complicates 6–10% of pregnancies with a major contribution to the worldwide maternal mortality rate. The aim of the current study was to evaluate the pregnancy outcomes in women with Hypertension disorders. Materials and Methods: This cross-sectional study was carried out on women with hypertension disorders enrolled in the department of Gynecology, Mardan Women Hospital, Sheikh Maltoon Town, Mardan and Family Health Centre, Peshawar from March 2021 to August 2021. Demographic details such as age, gestational age, parity, intrapartum, early postpartum complications such as perinatal outcomes and mode of delivery, and antepartum were recorded from each individual. Chi-square test was used for comparing the composite adverse outcomes such as preterm birth, postpartum hemorrhage, abrupt placenta, and mortality rate. SPSS version 20 was used for data analysis. Results: Of the total 2357 pregnant women, about 146 (6.2%) women had hypertensive disorders of pregnancy. The mean age of 146 pregnant women was 29.45±4.67 years with an age range from 17 to 43 years. About 37 (25.3%) women had no perinatal and maternal complications. Out of 109 pregnant women, the prevalence of eclampsia, preeclampsia, and pregnancy-induced hypertension were 8 (7.3%), 44 (40.4%), and 57 (52.3%) respectively. Based on gestational age, preterm (24-36 weeks) and term (>37 weeks) were 35 (32.1%) and 74 (67.9%) respectively. Other maternal complications were Abruption Placentae, Postpartum hemorrhage (PPH), Renal Failure., Pulmonary Edema, Disseminated intravascular coagulation (DIC), and Maternal Death. Conclusion: Our study found hypertension disorders as a significant medical disorder in pregnant women. However, neonatal outcomes and pregnancy outcomes were significantly smooth in more than 50% of pregnant women. Keywords: Hypertensive disorders of pregnancy, Pre-eclampsia, Eclampsia.

Sign in / Sign up

Export Citation Format

Share Document