scholarly journals Effects of intravenous butaphosphan and cyanocobalamin to late pregnant ewes on the metabolic indices around parturition and weight gain of their lambs after birth

2021 ◽  
Author(s):  
Azizollah Mohammadi Barimanloo ◽  
Aliasghar Chalmeh ◽  
Mehrdad Pourjafar ◽  
Abdolah Mirzaei
Keyword(s):  
Weight Gain ◽  
Metabolic Indices

scholarly journals Results of a 16-week safety assurance study with rats fed genetically modified Bt maize: effect on growth and health parameters

2018 ◽  
Vol 62 (4) ◽  
pp. 555-561 ◽  
Author(s):  
Beata Szymczyk ◽  
Witold Szczurek ◽  
Sylwester Świątkiewicz ◽  
Krzysztof Kwiatek ◽  
Zbigniew Sieradzki ◽  
...  
Keyword(s):  
Weight Gain ◽  
Body Weight Gain ◽  
Genetically Modified ◽  
Clinical Pathology ◽  
E Coli ◽  
Safety Assurance ◽  
Biochemical Indices ◽  
Metabolic Indices ◽  
Hybrid Maize ◽  
Mon 810

AbstractIntroduction: The influence of feeding genetically modified MON 810 hybrid maize on the growth and haematological and biochemical indices of rats was tested.Material and Methods: Two conventional (non-GM) and two test (MON 810) lines of maize were used in semi-purified diets at the level of 40% w/w. The non-GM I, MON 810 I, non-GM II, and MON 810 II maize lines were near-isogenic. A total of 40 male 6-week-old Wistar-derived rats were assigned to four equal feeding groups corresponding to the four maize lines for 16 weeks. Overall, health, body weight gain, clinical pathology parameters, gross changes, and appearance of tissues were compared between groups.Results: There were no statistically significant differences in the weight gain or relative organ weights of rats, but there were some non diet-related histopathological changes in the liver, kidneys, and spleen. Except for creatinine level, no diet-related effects were observed in haematology or most of the biochemical indices. Transgenic DNA of MON 810 maize was not detected in the tissues or faeces nor in the DNA of E. coli isolated from the rectum digesta of rats given transgenic feeds. In our experiment, various metabolic indices of rats fed non-GM diets or genetically modified (MON 810) maize for 16 weeks were similar. No adverse nutrition-related health effects were detected.Conclusion: MON 810 maize seems to be as safe as the conventional maize lines.

High-fat diet reduces weight gain but increases other cardio-metabolic indices in offspring of normotensive and hypertensive rats

2017 ◽  
Vol 124 (3) ◽  
pp. 218-225
Author(s):  
Oladele Ayobami Afolabi ◽  
Abdullateef Isiaka Alagbonsi ◽  
Roseline Toyosi Oyinloye ◽  
Hussein Mofomosara Salahdeen ◽  
Toyin Mohammed Salman ◽  
...  
Keyword(s):  
Weight Gain ◽  
High Fat Diet ◽  
High Fat ◽  
Hypertensive Rats ◽  
Metabolic Indices

scholarly journals 1049. Weight Gain in Persons Living with HIV (PLWH) Treated with Bictegravir Compared to Other Integrase Strand Transfer Inhibitors

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S554-S554
Author(s):  
Michelle Fang ◽  
Ariel Ma ◽  
Scott T Johns ◽  
Jonathan Lacro
Keyword(s):  
Weight Gain ◽  
Weight Change ◽  
Study Groups ◽  
Strand Transfer ◽  
Chi Square ◽  
Persons Living With Hiv ◽  
Group 3 ◽  
Group 2 ◽  
Metabolic Indices ◽  
Group 1

Abstract Background Recent studies have given rise to the concern that some integrase strand transfer inhibitor (INSTI)-based antiretroviral therapy may lead to weight gain in PLWH. The objectives of this study were to compare the incidence of weight gain following initiation of bictegravir (BIC) compared to other INSTIs, and to assess whether any differences were associated with changes in metabolic indices. Methods Patients from the VA San Diego Healthcare System (VASDHS) were included in this retrospective cohort study if they were at least 18 years old and being treated for HIV with an INSTI that was started exclusively with FTC/TAF for at least 6 months. INSTI-containing regimens were excluded if initiated with non-FTC/TAF antiretroviral agents or if the patient was pregnant, using prescription weight loss drugs, or did not have weights recorded after the start of the studied regimen. The primary outcome was weight gain at 12 and 18 months after the start of the studied regimen. Secondary outcomes included changes in parameters used to define metabolic syndrome. Statistical analysis was performed using Mann-Whitney U, Chi-square, and Spearman’s Rho tests. Results 560 patients with 809 instances of new INSTI prescriptions from VASDHS during November 2015 to October 2019 were reviewed for inclusion. Raltegravir-based regimens were excluded from analysis due to the limited number of eligible regimens. Study groups included group 1 (BIC, n=265), group 2 (elvitegravir/cobicistat, n=123), and group 3 (dolutegravir, n=35). There were no significant differences in baseline weight between groups. Median weight change at 12 months was 2.8 lbs. in group 1, 4.4 lbs. in group 2 (p=0.328 vs. group 1), and 5.3 lbs. in group 3 (p=0.133 vs. group 1). At 18 months, median weight change was 4.5 lbs. in group 1, 3.4 lbs. in group 2 (p=0.597 vs. group 1), and 7.7 lbs. in group 3 (p=0.585 vs. group 1). Within group 1, there was a significant increase in weight at 3, 6, 12, and 18 months compared to index date. Conclusion These results support the growing body of evidence associating INSTI use with weight gain, which was persistent over 18 months in all groups and in the context of a consistent FTC/TAF backbone in this study. No significant differences in magnitude of weight gain were observed between INSTIs. Disclosures All Authors: No reported disclosures

Genes Play Role In Weight-Gain Risk, Behaviors

2008 ◽  
Vol 42 (5) ◽  
pp. 30
Author(s):  
Kerri Wachter
Keyword(s):  
Weight Gain ◽  
Risk Behaviors

Weight Gain May Save a Heart Failure Patient's Life

2006 ◽  
Vol 39 (1) ◽  
pp. 39
Author(s):  
MITCHEL L. ZOLER
Keyword(s):  
Heart Failure ◽  
Weight Gain

Study Exonerates High-Carb Diets as Weight-Gain Cause in Older Women

2006 ◽  
Vol 39 (3) ◽  
pp. 27
Author(s):  
MARY ANN MOON
Keyword(s):  
Weight Gain ◽  
Older Women

Prevention of Weight Gain Is as Important as Weight Loss

2007 ◽  
Vol 40 (9) ◽  
pp. 12
Author(s):  
SHERRY BOSCHERT
Keyword(s):  
Weight Loss ◽  
Weight Gain

Abstract #534 Influence of Gestational Weight Gain and Pre-Pregnancy Body Mass Index on Birth Weight

2019 ◽  
Vol 25 ◽  
pp. 268-269
Author(s):  
Bolanle Okunowo ◽  
Ifedayo Odeniyi ◽  
Oluwarotimi Olopade ◽  
Olufemi Fasanmade ◽  
Omololu Adegbola ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Weight Gain ◽  
Birth Weight ◽  
Gestational Weight Gain ◽  
Body Mass ◽  
Gestational Weight

Weight Gain May Not Follow Addition of Insulin Therapy

2008 ◽  
Vol 3 (2) ◽  
pp. 8
Author(s):  
MICHELE G. SULLIVAN
Keyword(s):  
Weight Gain ◽  
Insulin Therapy
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