scholarly journals Orotic acid production by Yarrowia lipolytica under conditions of limited pyrimidine

Yeast ◽  
2021 ◽  
Author(s):  
Paul Swietalski ◽  
Frank Hetzel ◽  
Iris Klaiber ◽  
Eva Pross ◽  
Ines Seitl ◽  
...  
Keyword(s):  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Orotic Acid

Metabolic engineering for ricinoleic acid production in the oleaginous yeast Yarrowia lipolytica

2013 ◽  
Vol 98 (1) ◽  
pp. 251-262 ◽  
Author(s):  
A. Beopoulos ◽  
J. Verbeke ◽  
F. Bordes ◽  
M. Guicherd ◽  
M. Bressy ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Ricinoleic Acid ◽  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Oleaginous Yeast ◽  
Yeast Yarrowia Lipolytica

scholarly journals Experimental Design as a Tool for the Development of Citric Acid Production by Yarrowia lipolytica Using Glycerol as a Feedstock

2013 ◽  
Vol 3 (8) ◽  
Author(s):  
Luana V. da Silva ◽  
Camila B. Tavares ◽  
Roberta dos R. Ribeiro ◽  
Fernando L. P. Pessoa ◽  
Maria Alice Z. Coelho ◽  
...  
Keyword(s):  
Citric Acid ◽  
Experimental Design ◽  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Citric Acid Production

Hydrolysis of fruit and vegetable waste for efficient succinic acid production with engineered Yarrowia lipolytica

2018 ◽  
Vol 179 ◽  
pp. 151-159 ◽  
Author(s):  
Chong Li ◽  
Xiaofeng Yang ◽  
Shi Gao ◽  
Augustine Harmony Chuh ◽  
Carol Sze Ki Lin
Keyword(s):  
Succinic Acid ◽  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Vegetable Waste ◽  
Fruit And Vegetable ◽  
Succinic Acid Production ◽  
Hydrolysis Of

Non-Photosynthetic CO2 Utilization to Increase Fatty Acid Production in Yarrowia lipolytica

2021 ◽  
Vol 69 (40) ◽  
pp. 11912-11918
Author(s):  
Seung Kyou You ◽  
Hyeon Min Park ◽  
Myeong-Eun Lee ◽  
Young Jin Ko ◽  
Dong-Hyeuk Hwang ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Co2 Utilization ◽  
Fatty Acid Production

scholarly journals Genome-scale model-driven strain design for dicarboxylic acid production in Yarrowia lipolytica

2018 ◽  
Vol 12 (S2) ◽  
Author(s):  
Pranjul Mishra ◽  
Na-Rae Lee ◽  
Meiyappan Lakshmanan ◽  
Minsuk Kim ◽  
Byung-Gee Kim ◽  
...  
Keyword(s):  
Dicarboxylic Acid ◽  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Scale Model ◽  
Model Driven ◽  
Strain Design ◽  
Genome Scale ◽  
Genome Scale Model

scholarly journals Physiological Characterization of a Novel Wild-Type Yarrowia lipolytica Strain Grown on Glycerol: Effects of Cultivation Conditions and Mode on Polyols and Citric Acid Production

2020 ◽  
Vol 10 (20) ◽  
pp. 7373
Author(s):  
Seraphim Papanikolaou ◽  
Panagiota Diamantopoulou ◽  
Fabrice Blanchard ◽  
Eleni Lambrinea ◽  
Isabelle Chevalot ◽  
...  
Keyword(s):  
Citric Acid ◽  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Unsaturated Fatty Acids ◽  
Citric Acid Production ◽  
Wild Type ◽  
Alcohol Production ◽  
Physiological Characterization ◽  
Batch Bioreactor ◽  
New Yeast

A new yeast wild-type Yarrowia lipolytica isolate presented efficient growth on glycerol. During flask cultures, nitrogen limitation led to the secretion of sugar-alcohols as the major metabolites of the process (mannitol, arabitol and erythritol), whereas insignificant quantities of citrate were synthesized. Although in some instances high initial glycerol concentrations were employed (≈150 g/L), remarkable glycerol assimilation and polyol secretion was observed. Total polyols ≈ 52 g/L (conversion yield on glycerol consumed = 0.43 g/g) was recorded in the flask experiments. The sugar-alcohol production bioprocess was successfully simulated with the aid of a modified Velhlust–Aggelis model that fitted very well with the experimental data, while optimized parameter values seemed to be quite consistent. In bioreactor trials, a noticeable metabolic shift towards citric acid production was observed, while simultaneously insignificant polyol quantities were produced. In fed-batch bioreactor experiments, a total citric acid quantity ≈ 102 g/L was recorded—one of the highest in the literature for wild-type Y. lipolytica strains. This metabolic transition was due to higher oxygen saturation into the medium that occurred in the bioreactor experiments compared with the flasks. Cellular lipids produced in the bioreactor trial contained higher concentrations of unsaturated fatty acids compared with those produced in flasks.

Characterization of Yarrowia lipolytica and related species for citric acid production from glycerol

2007 ◽  
Vol 41 (3) ◽  
pp. 292-295 ◽  
Author(s):  
William E. Levinson ◽  
Cletus P. Kurtzman ◽  
Tsung Min Kuo
Keyword(s):  
Citric Acid ◽  
Yarrowia Lipolytica ◽  
Related Species ◽  
Acid Production ◽  
Citric Acid Production
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