Red Blood Cells from Alzheimer Patients and from Normal Subjects Discerned by Cell Electrophoresis in an Aqueous Polymer Solution

1993 ◽  
Vol 194 (1) ◽  
pp. 23-28 ◽  
Author(s):  
H. Walter ◽  
K.E. Widen ◽  
S.L. Read
2003 ◽  
Vol 29 (1) ◽  
pp. 144-146 ◽  
Author(s):  
Hironobu Imakoma ◽  
Ryo Omori ◽  
Katsuyuki Kubota ◽  
Masamichi Yoshida

2002 ◽  
Vol 28 (4) ◽  
pp. 488-489 ◽  
Author(s):  
Hironobu Imakoma ◽  
Tatsuhiro Nakazawa ◽  
Katsuyuki Kubota ◽  
Masamichi Yoshida

2003 ◽  
Vol 29 (5) ◽  
pp. 695-697 ◽  
Author(s):  
Hironobu Imakoma ◽  
Takeshi Mori ◽  
Katsuyuki Kubota ◽  
Masamichi Yoshida

1976 ◽  
Vol 128 (2) ◽  
pp. 184-187 ◽  
Author(s):  
Helen L. White ◽  
Malcolm N. McLeod ◽  
Jonathan R. T. Davidson

SummaryCatechol O-methyltransferase of lysed human red blood cells was assayed under optimal conditions, using saturating concentrations of the substrates, S-adenosyl-L-methionine and 3,4-dihydroxybenzoic acid. The mean enzyme activity found in 24 normal subjects was 29.2 nmol/hr/ml RBC. The mean activity in blood of 33 female unipolar depressives was not significantly different from normal. However, higher enzyme activities were observed in the blood of 11 schizophrenic patients (38.9 nmol/hr/ml RBC). Partially purified enzyme preparations from blood of normal and schizophrenic individuals were indistinguishable with respect to substrate specificities, isoelectric pH values, and ratios of the two O-methylated products. Therefore it is unlikely that any defect in O-methylation which may occur in schizophrenia can be attributed to a change in the intrinsic properties of erythrocyte catechol O-methyltransferase.


1992 ◽  
Vol 97 (11) ◽  
pp. 8722-8726 ◽  
Author(s):  
Nobuhiro Miura ◽  
Naoki Shinyashiki ◽  
Satoru Mashimo

Sign in / Sign up

Export Citation Format

Share Document