Nitric Oxide Inhibition Increases Aortic Wall Matrix Metalloproteinase-9 Expression

2002 ◽  
Vol 104 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Matthew J. Eagleton ◽  
David A. Peterson ◽  
Vita V. Sullivan ◽  
Karen J. Roelofs ◽  
John A. Ford ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Matrix Metalloproteinase ◽  
Aortic Wall ◽  
Matrix Metalloproteinase 9 ◽  
Nitric Oxide Inhibition ◽  
Metalloproteinase 9 ◽  
Oxide Inhibition

scholarly journals Nitric oxide inhibition increases matrix metalloproteinase–9 expression by rat aortic smooth muscle cells in vitro

2001 ◽  
Vol 34 (1) ◽  
pp. 76-83 ◽  
Author(s):  
Gilbert R. Upchurch ◽  
John W. Ford ◽  
Steven J. Weiss ◽  
Brian S. Knipp ◽  
David A. Peterson ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Smooth Muscle ◽  
Matrix Metalloproteinase ◽  
Smooth Muscle Cells ◽  
Muscle Cells ◽  
Nitric Oxide Inhibition ◽  
Aortic Smooth Muscle ◽  
Metalloproteinase 9 ◽  
Oxide Inhibition

scholarly journals Matrix metalloproteinase-9 increases and Interleukin-10 reduces with increase in body mass index in polycystic ovary syndrome: A cross-sectional study

2020 ◽  
Author(s):  
Angel Mercy Sylus ◽  
Hanumanthappa Nandeesha ◽  
Thiagaraju Chitra
Keyword(s):  
Nitric Oxide ◽  
Body Mass Index ◽  
Polycystic Ovary Syndrome ◽  
Matrix Metalloproteinase ◽  
Body Mass ◽  
Polycystic Ovary ◽  
Interleukin 10 ◽  
Matrix Metalloproteinase 9 ◽  
Ovary Syndrome ◽  
Metalloproteinase 9

Background: Obesity, inflammation and alterations in matrix metalloproteinase-9 (MMP-9) and nitric oxide (NO) levels are involved in the development of polycystic ovary syndrome (PCOS). Objective: To investigate the relationship of MMP-9, NO and interleukin-10 (IL-10) with the increase in body mass index (BMI) in women with PCOS. Materials and Methods: Sixty two infertile PCOS women were included in the study. Serum levels of NO, IL-10 and MMP-9 were assessed in the women with increase in BMI. Results: MMP-9 was significantly increased (p = 0.029) and IL-10 (p = 0.015) was significantly reduced in obese PCOS subjects compared to those with lesser BMI. MMP- 9 levels positively correlated with the duration of infertility (r = 0.253, p = 0.047) and negatively correlated with NO levels (r = - 0.259, p = 0.042). A significant negative correlation between the interleukin-10 levels and the BMI (r = - 0.272, p = 0.033) was also found in the PCOS subjects. Conclusion: MMP-9 levels are increased in obese PCOS women and it is associated with NO levels and the duration of infertility. Key words: Body mass index, Interleukin-10, Nitric oxide, Matrix metalloproteinase-9.

scholarly journals Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways

2007 ◽  
Vol 104 (43) ◽  
pp. 16898-16903 ◽  
Author(s):  
L. A. Ridnour ◽  
A. N. Windhausen ◽  
J. S. Isenberg ◽  
N. Yeung ◽  
D. D. Thomas ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Matrix Metalloproteinase ◽  
Guanylyl Cyclase ◽  
Matrix Metalloproteinase 9 ◽  
Metalloproteinase 9

Down-regulation of matrix metalloproteinase-9 expression by nitric oxide in lipopolysaccharide-stimulated rat primary astrocytes

Nitric Oxide ◽  
2007 ◽  
Vol 16 (4) ◽  
pp. 425-432 ◽  
Author(s):  
Chan Young Shin ◽  
Woo Jong Lee ◽  
Ji Woong Choi ◽  
Min Sik Choi ◽  
Jae Ryun Ryu ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Matrix Metalloproteinase ◽  
Matrix Metalloproteinase 9 ◽  
Down Regulation ◽  
Primary Astrocytes ◽  
Metalloproteinase 9

Molecular mechanisms of nitric oxide-dependent inhibition of TPA-induced matrix metalloproteinase-9 (MMP-9) in MCF-7 cells

2009 ◽  
Vol 219 (2) ◽  
pp. 276-287 ◽  
Author(s):  
Christine Jespersen ◽  
Anke Doller ◽  
El-Sayed Akool ◽  
Malte Bachmann ◽  
Roswitha Müller ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Matrix Metalloproteinase ◽  
Molecular Mechanisms ◽  
Matrix Metalloproteinase 9 ◽  
Dependent Inhibition ◽  
Metalloproteinase 9 ◽  
Mcf 7

Nitric Oxide and Cyclic GMP Increase the Expression of Matrix Metalloproteinase-9 in Vascular Smooth Muscle

2003 ◽  
Vol 307 (1) ◽  
pp. 429-436 ◽  
Author(s):  
Marcelo Marcet-Palacios ◽  
Kathryn Graham ◽  
Carol Cass ◽  
A. Dean Befus ◽  
Irvin Mayers ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Smooth Muscle ◽  
Matrix Metalloproteinase ◽  
Vascular Smooth Muscle ◽  
Cyclic Gmp ◽  
Matrix Metalloproteinase 9 ◽  
Metalloproteinase 9
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