Hopes of Patients with Behçet’s Disease in Japan Towards Researchers and the Relationship between Patients and Medical Staff Concerning Social Work

2006 ◽  
pp. 605-608
Author(s):  
Tomomi Nishida ◽  
Minoru Nishida ◽  
Michiko Wakayama ◽  
Masumi Nishida ◽  
Shigeaki Ohno
Keyword(s):  
Social Work ◽  
Behçet’S Disease ◽  
Medical Staff ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease ◽  
The Relationship

scholarly journals Safety of radiotherapy in patients with Behcet’s disease: a case report and review of the literature

2021 ◽  
Vol 18 (2) ◽  
pp. 35-39
Author(s):  
Dahui Ko ◽  
Young Suk Kim ◽  
Yunseon Choi
Keyword(s):  
Connective Tissue ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Connective Tissue Diseases ◽  
Review Of The Literature ◽  
Behcet's Disease ◽  
Radiation Induced ◽  
Radiotherapy Toxicity ◽  
The Relationship

Exaggerated acute and late toxicities following radiotherapy have been reported in patients with pre-existing connective tissue diseases, such as systemic lupus and scleroderma. Behcet’s disease (BD) is a relapsing multisystem connective tissue disease characterized by vasculitis in the mucocutaneous, ocular, gastrointestinal, respiratory, neurologic, urogenital, articular, and cardiovascular systems. Data concerning the relationship between radiotherapy toxicity and BD are limited in the literature. Here, we report a case of lung cancer treated with radiotherapy (60 Gy) in a patient with BD. No severe radiation-induced toxicity was observed. Radiation-induced toxicity in patients with BD has also been discussed.

scholarly journals Behçet’s disease: new insight into the relationship between procoagulant state, endothelial activation/damage and disease activity

2013 ◽  
Vol 8 (1) ◽  
pp. 81 ◽  
Author(s):  
Ihosvany Fernández-Bello ◽  
Francisco J López-Longo ◽  
Elena G Arias-Salgado ◽  
Víctor Jiménez-Yuste ◽  
Nora V Butta
Keyword(s):  
Disease Activity ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Endothelial Activation ◽  
Behcet's Disease ◽  
The Relationship ◽  
Insight Into

Examination of the Relationship between the Hepatitis C Virus and Behçet's Disease

2004 ◽  
Vol 31 (5) ◽  
pp. 442-443 ◽  
Author(s):  
Meral Sönmezoglu ◽  
Emine Derviş ◽  
Selim Badur ◽  
O.Şadi Yenen
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease ◽  
The Relationship

scholarly journals Vasculitis damage index in Behçet’s disease

2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Fatema T. Elgengehy ◽  
Sherif M. Gamal ◽  
Nesreen Sobhy ◽  
Ibrahem Siam ◽  
Ahmed M. Soliman ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Immunosuppressive Treatment ◽  
Damage Index ◽  
Clinical Manifestations ◽  
Behcet's Disease ◽  
Vasculitis Damage Index ◽  
Relationship Of ◽  
The Relationship

Abstract Background Vasculitis damage index (VDI) is a validated damage index for systemic vasculitis, and as Behçet’s disease is considered one of systemic vascular disease we aimed to study the relationship of the vasculitis damage index to clinical manifestations and comorbidity in patients with Behçet’s disease (BD) to determine if VDI could be used to assess damage in patients with BD. Methods A total of 109 patients with BD were recruited from the Rheumatology Department (outpatient and inpatient clinic), Cairo University Hospitals. All patients were subjected to full history taking, clinical examination, and routine laboratory investigations. Disease activity was assessed by the BD current activity form, and the VDI was calculated in all patients. The relationship of the VDI to the disease clinical manifestations was studied. Mann–Whitney and Kruskal Wallis tests were used to estimate differences in quantitative variables. Spearman correlation test was used to test for correlation between quantitative variables. Results In the current study, the VDI ranged from 1 to 10, with a mean of 3.5 ± 1.8. It was significantly associated with total thrombosis (P = 0.022); total neurological manifestations (P = 0.000), especially stroke and cranial nerve affection; uveitis (P = 0.005); avascular necrosis (AVN) (P = 0.015); osteoporosis (P = 0.01); impaired vision (P < 0.0001); cataract (P < 0.0001); and diabetes (P = 0.012). Generally, immunosuppressive treatment was significantly associated with VDI (P = 0.039), especially cyclophosphamide (P < 0.0001), biological agent (P = 0.008), chlorambucil (P = 0.003), and anticoagulant (P = 0.02). VDI was also significantly correlated with age (P = 0.033), disease duration (P = 0.029), and duration of eye involvement (P = 0.003). Conclusion VDI is significantly associated with most disease parameters of BD, except for parameters such as mucocutaneous manifestations and uncomplicated venous thrombosis; however, further studies may be needed to establish BD-specific damage index.

scholarly journals The relationship of HLA class I and II phenotypes to clinical features of Behcet's disease.

1990 ◽  
Vol 13 (2) ◽  
pp. 142-148 ◽  
Author(s):  
Kazuyuki Morita ◽  
Junko Moriuchi ◽  
Yukinobu Ichikawa ◽  
Kimiyoshi Tsuji ◽  
Shigeru Arimori
Keyword(s):  
Clinical Features ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Hla Class I ◽  
Class I ◽  
Behcet's Disease ◽  
Relationship Of ◽  
The Relationship

scholarly journals Pharmacotherapy for Behçet’s Disease and the Risk of Malignancy

2021 ◽  
Vol 12 ◽  
Author(s):  
Mao-Xin Huang ◽  
Cai-Yun Wang ◽  
Jin-Yan Guo ◽  
Jian-Hao Li ◽  
Xiao-Hong Li ◽  
...  
Keyword(s):  
High Risk ◽  
Protective Factors ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Control Group ◽  
Behcet's Disease ◽  
Increased Risk ◽  
Risk Of Cancer ◽  
The Relationship

Background: Behçet’s disease (BD) is associated with an increased risk of cancer. Few reports have been published on the relationship between drug exposure and the risk of cancer in patients with BD. Herein, we explored the relationship between pharmacologic interventions for BD and the risk of cancer.Methods: we carried out a retrospective nested case-control study in a cohort of BD patients from attending our institution. Among 1,148 patients, 22 cancer patients were individually 1:2 matched to 44 cancer-free controls. The following biochemical indicators were evaluated: routine blood analysis, liver and kidney function tests, inflammatory indexes, blood gas analysis, blood electrolyte and previous pharmacologic interventions to manage BD including systemic glucocorticoids, methotrexate, cyclosporine-A, azathioprine, cyclophosphamide (CYC), and thalidomide, which are considered the primary medicines used for the management of BD.Results: Among the 22 BD patients with cancers, myelodysplastic syndrome (MDS) (22.72%) was the most common type. Furthermore, CYC administration was significantly higher in BD patients with cancer compared with the cancer-free matched control group. Further, we observed that complement 4 (C4) (odds ratio [OR] = 0.0001, 95% confidence interval [CI]: 0.001–0.065) and hemoglobin (Hb) (OR = 0.891, 95% CI: 0.795–0.998) levels were independent protective factors for predicting cancer risk in BD patients on multivariate analyses.Conclusion: Our study revealed that CYC was associated with a high risk of cancer in BD patients. Furthermore, C4 and Hb are independent protective factors for oncogenesis in BD patients. These findings may provide references and suggestions for clinicians to select appropriate treatments and for the early recognition of high-risk patients to reduce cancer incidence in BD patients.

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