Design, Simulation, and Experimental Demonstration of Self-assembled DNA Nanostructures and Motors

2005 ◽  
pp. 173-187 ◽  
Author(s):  
John H. Reif ◽  
Thomas H. LaBean ◽  
Sudheer Sahu ◽  
Hao Yan ◽  
Peng Yin
Keyword(s):  
Dna Nanostructures ◽  
Experimental Demonstration ◽  
Self Assembled

Understanding Self-Assembled Pseudoisocyanine Dye Aggregates in DNA Nanostructures and Their Exciton Relay Transfer Capabilities

2021 ◽  
Author(s):  
Matthew Chiriboga ◽  
Sebastian A. Diaz ◽  
Divita Mathur ◽  
David A. Hastman ◽  
Joseph S. Melinger ◽  
...  
Keyword(s):  
Dna Nanostructures ◽  
Self Assembled

Self-Assembled DNA Nanostructures-Based Nanocarriers Enabled Functional Nucleic Acids Delivery

2020 ◽  
Vol 3 (5) ◽  
pp. 2779-2795 ◽  
Author(s):  
Jin Huang ◽  
Wenjie Ma ◽  
Huanhuan Sun ◽  
Huizhen Wang ◽  
Xiaoxiao He ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Dna Nanostructures ◽  
Self Assembled ◽  
Nucleic Acids Delivery ◽  
Functional Nucleic Acids

Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs

2016 ◽  
Vol 243 ◽  
pp. 121-131 ◽  
Author(s):  
Kyoung-Ran Kim ◽  
Hyo Young Kim ◽  
Yong-Deok Lee ◽  
Jong Seong Ha ◽  
Ji Hee Kang ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Dna Nanostructures ◽  
Self Assembled

scholarly journals In situ Surface Charge Density Visualization of Self‐assembled DNA Nanostructures after Ion Exchange

ChemPhysChem ◽  
2020 ◽  
Vol 21 (13) ◽  
pp. 1474-1482 ◽  
Author(s):  
Steffan Møller Sønderskov ◽  
Lasse Hyldgaard Klausen ◽  
Sebastian Amland Skaanvik ◽  
Xiaojun Han ◽  
Mingdong Dong
Keyword(s):  
Ion Exchange ◽  
Charge Density ◽  
Surface Charge ◽  
Surface Charge Density ◽  
Dna Nanostructures ◽  
Self Assembled

Smart Drug Delivery Nanocarriers with Self-Assembled DNA Nanostructures

2013 ◽  
Vol 25 (32) ◽  
pp. 4386-4396 ◽  
Author(s):  
Jiang Li ◽  
Chunhai Fan ◽  
Hao Pei ◽  
Jiye Shi ◽  
Qing Huang
Keyword(s):  
Drug Delivery ◽  
Dna Nanostructures ◽  
Self Assembled ◽  
Smart Drug ◽  
Smart Drug Delivery

scholarly journals FOLDNA, a Web Server for Self-Assembled DNA Nanostructure Autoscaffolds and Autostaples

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Chensheng Zhou ◽  
Heng Luo ◽  
Xiaolu Feng ◽  
Xingwang Li ◽  
Jie Zhu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Dna Sequences ◽  
Self Assembly ◽  
Web Server ◽  
Automatic Design ◽  
Dna Nanostructures ◽  
Complementary Dna ◽  
Dna Nanostructure ◽  
Comprehensive Information ◽  
Self Assembled

DNA self-assembly is a nanotechnology that folds DNA into desired shapes. Self-assembled DNA nanostructures, also known as origami, are increasingly valuable in nanomaterial and biosensing applications. Two ways to use DNA nanostructures in medicine are to form nanoarrays, and to work as vehicles in drug delivery. The DNA nanostructures perform well as a biomaterial in these areas because they have spatially addressable and size controllable properties. However, manually designing complementary DNA sequences for self-assembly is a technically demanding and time consuming task, which makes it advantageous for computers to do this job instead. We have developed a web server, FOLDNA, which can automatically design 2D self-assembled DNA nanostructures according to custom pictures and scaffold sequences provided by the users. It is the first web server to provide an entirely automatic design of self-assembled DNA nanostructure, and it takes merely a second to generate comprehensive information for molecular experiments including: scaffold DNA pathways, staple DNA directions, and staple DNA sequences. This program could save as much as several hours in the designing step for each DNA nanostructure. We randomly selected some shapes and corresponding outputs from our server and validated its performance in molecular experiments.

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