Electron Microscopy of the Brains of Drosophila Models of Alzheimer’s Diseases

2015 ◽  
pp. 105-123
Author(s):  
Kanae Ando ◽  
Stephen Hearn ◽  
Emiko Suzuki ◽  
Akiko Maruko-Otake ◽  
Michiko Sekiya ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Alzheimer’S Diseases ◽  
Drosophila Models ◽  
Alzheimer's Diseases

scholarly journals COVID-19 in age-related neurodegenerative diseases: is there a role for vitamin D3 as a possible therapeutic strategy?

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Milena de Barros Viana ◽  
Bárbara dos Anjos Rosário ◽  
Maria de Fátima Santana de Nazaré ◽  
Débora Estadella ◽  
Daniel Araki Ribeiro ◽  
...  
Keyword(s):  
Vitamin D ◽  
Therapeutic Strategy ◽  
Clinical Symptoms ◽  
Large Population ◽  
Mortality Rates ◽  
Vitamin D Supplementation ◽  
World Health ◽  
Age Related ◽  
Alzheimer’S Diseases ◽  
Alzheimer's Diseases

AbstractThe coronavirus disease (COVID-19), identified in Wuhan, China, on December 2019, was declared a pandemic by the World Health Organization, on March, 2020. Since then, efforts have been gathered to describe its clinical course and to determine preventive measures and treatment strategies. Adults older than 65 years of age are more susceptible to serious clinical symptoms and present higher mortality rates. Angiotensin-converting enzyme 2 (ACE2) is a major receptor for some coronavirus infection, including SARS-COV-2, but is also a crucial determinant in anti-inflammation processes during the renin–angiotensin system (RAS) functioning – converting angiotensin II to angiotensin 1–7. The decline in ACE2 expression that occurs with aging has been associated to the higher morbidity and mortality rates in older adults. These observations highlight the importance of investigating the association between COVID-19 and age-related neurodegenerative disorders, i.e., Parkinson’s and Alzheimer’s diseases. A possible option to reduce the risk of COVID-19 is vitamin D supplementation, due to its anti-inflammatory and immune-system-modulating effects. It has also been suggested that vitamin D supplementation plays a role in slowing progression of Parkinson and Alzheimer. The present study is a literature review of articles published on the theme COVID-19, Parkinson and Alzheimer’s diseases, and the role played by vitamin D. PUBMED, MEDLINE, and EMBASE databases were consulted. Results confirm neurodegenerative and neuroinflammatory effects of COVID-19, aggravated in Parkinson’s and Alzheimer’s patients, and the important role of vitamin D as a possible therapeutic strategy. Nevertheless, randomized controlled trials and large population studies are still warranted.

scholarly journals Therapeutic approaches for prion and Alzheimer's diseases

FEBS Journal ◽  
2007 ◽  
Vol 274 (15) ◽  
pp. 3784-3798 ◽  
Author(s):  
Thomas Wisniewski ◽  
Einar M. Sigurdsson
Keyword(s):  
Therapeutic Approaches ◽  
Alzheimer’S Diseases ◽  
Alzheimer's Diseases

scholarly journals Different Approaches, One Target: Understanding Cellular Mechanisms of Parkinson's and Alzheimer's Diseases

2012 ◽  
Vol 34 ◽  
pp. 194-218 ◽  
Author(s):  
Andréa S. Torrão ◽  
Cecilia C. Café-Mendes ◽  
Caroline C. Real ◽  
Marina S. Hernandes ◽  
Ana F.B. Ferreira ◽  
...  
Keyword(s):  
Cellular Mechanisms ◽  
Alzheimer’S Diseases ◽  
Alzheimer's Diseases

Plasma catechols and monoamine oxidase metabolites in untreated Parkinson's and Alzheimer's diseases

1996 ◽  
Vol 136 (1-2) ◽  
pp. 162-168 ◽  
Author(s):  
J.Eric Ahlskog ◽  
Ryan J. Uitti ◽  
Gertrude M. Tyce ◽  
John F. O'Brien ◽  
Ronald C. Petersen ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Alzheimer’S Diseases ◽  
Alzheimer's Diseases

scholarly journals Whole transcriptome cerebral cortex gene analysis in Alzheimer’s diseases

2016 ◽  
Author(s):  
S. Pooja ◽  
Anitha P. Muttagi ◽  
Seema J. Patel ◽  
H. Gurumurthy ◽  
Prashantha Nagaraja
Keyword(s):  
Cerebral Cortex ◽  
Gene Analysis ◽  
Alzheimer’S Diseases ◽  
Whole Transcriptome ◽  
Alzheimer's Diseases

Investigation of Changes in the Microviscosity of the Erythrocyte Membranes and Glutathione in the Plasma of Animals with an Experimental Pathology Type Alzheimer’s Diseases

2021 ◽  
Vol 15 (1) ◽  
pp. 112-118
Author(s):  
N. Yu. Gerasimov ◽  
G. F. Ivanenko ◽  
N. V. Bobkova ◽  
O. V. Nevrova ◽  
A. N. Goloshchapov
Keyword(s):  
Erythrocyte Membranes ◽  
Experimental Pathology ◽  
Alzheimer’S Diseases ◽  
Alzheimer's Diseases

scholarly journals P2-233: NOVEL HIGHLY-SENSITIVE METHOD FOR THE IDENTIFICATION OF ALZHEIMER'S DISEASES WITH HUMAN BLOOD

2019 ◽  
Vol 15 ◽  
pp. P669-P669
Author(s):  
Kyeong-Sik Shin ◽  
Miso Kim ◽  
Youhee Heo ◽  
Ji Yoon Kang
Keyword(s):  
Human Blood ◽  
Highly Sensitive ◽  
Alzheimer’S Diseases ◽  
Sensitive Method ◽  
Alzheimer's Diseases
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