Dynamic Plasticity

2009 ◽  
pp. 561-669 ◽  
Author(s):  
J. Chakrabarty
Keyword(s):  
Dynamic Plasticity

scholarly journals Mitochondrial Dynamics, ROS, and Cell Signaling: A Blended Overview

Life ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 332
Author(s):  
Valentina Brillo ◽  
Leonardo Chieregato ◽  
Luigi Leanza ◽  
Silvia Muccioli ◽  
Roberto Costa
Keyword(s):  
Molecular Mechanisms ◽  
Mitochondrial Dynamics ◽  
Eukaryotic Cells ◽  
Therapeutic Approaches ◽  
Cellular Functions ◽  
Lipid Trafficking ◽  
Mitochondrial Ros ◽  
Intracellular Organelles ◽  
Proliferation Regulation ◽  
Dynamic Plasticity

Mitochondria are key intracellular organelles involved not only in the metabolic state of the cell, but also in several cellular functions, such as proliferation, Calcium signaling, and lipid trafficking. Indeed, these organelles are characterized by continuous events of fission and fusion which contribute to the dynamic plasticity of their network, also strongly influenced by mitochondrial contacts with other subcellular organelles. Nevertheless, mitochondria release a major amount of reactive oxygen species (ROS) inside eukaryotic cells, which are reported to mediate a plethora of both physiological and pathological cellular functions, such as growth and proliferation, regulation of autophagy, apoptosis, and metastasis. Therefore, targeting mitochondrial ROS could be a promising strategy to overcome and hinder the development of diseases such as cancer, where malignant cells, possessing a higher amount of ROS with respect to healthy ones, could be specifically targeted by therapeutic treatments. In this review, we collected the ultimate findings on the blended interplay among mitochondrial shaping, mitochondrial ROS, and several signaling pathways, in order to contribute to the dissection of intracellular molecular mechanisms involved in the pathophysiology of eukaryotic cells, possibly improving future therapeutic approaches.

scholarly journals Author response: Macro-connectomics and microstructure predict dynamic plasticity patterns in the non-human primate brain

2018 ◽  
Author(s):  
Sean Froudist-Walsh ◽  
Philip GF Browning ◽  
James J Young ◽  
Kathy L Murphy ◽  
Rogier B Mars ◽  
...  
Keyword(s):  
Author Response ◽  
Primate Brain ◽  
Dynamic Plasticity ◽  
Human Primate

Dislocation Mechanics of Extremely High Rate Deformations in Iron and Tantalum

2021 ◽  
pp. 1-30
Author(s):  
Mu'Tasem Shehadeh ◽  
Pascale El Ters ◽  
Ronald W. Armstrong ◽  
Werner Arnold
Keyword(s):  
Strain Rate ◽  
Weak Shock ◽  
Rate Sensitivity ◽  
High Rate ◽  
Dislocation Dynamic ◽  
Dislocation Generation ◽  
High Deformation ◽  
Rate Analysis ◽  
Dislocation Mechanics ◽  
Dynamic Plasticity

Abstract High strain rate simulations were performed using the multiscale dislocation dynamic plasticity (MDDP) method to calculate different rise times and load durations in mimicking high deformation rate shock or isentropic (ramp) testing of a-iron and tantalum crystals. Focus for both types of loading on both materials was on the inter-relationship between the (dislocation-velocity-related) strain rate sensitivity and the (time-dependent) evolution of dislocation density. The computations are compared with model thermal activation strain rate analysis (TASRA), phonon drag and dislocation generation predictions. The overall comparison of simulated tests and previous experimental measurements shows that the imposition of a rise time even as small as 0.2 ns preceding plastic relaxation via the MDDP method is indicative of relatively weak shock behavior.

scholarly journals Dynamic plasticity of the lipid antigen-binding site of CD1d is crucially favoured by acidic pH and helper proteins

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Bruno Cuevas-Zuviría ◽  
Marina Mínguez-Toral ◽  
Araceli Díaz-Perales ◽  
María Garrido-Arandia ◽  
Luis F. Pacios
Keyword(s):  
Binding Site ◽  
Antigen Binding ◽  
Acidic Ph ◽  
Antigen Binding Site ◽  
Lipid Antigen ◽  
Dynamic Plasticity

scholarly journals Cytology of DNA Replication Reveals Dynamic Plasticity of Large-Scale Chromatin Fibers

2016 ◽  
Vol 26 (18) ◽  
pp. 2527-2534 ◽  
Author(s):  
Xiang Deng ◽  
Oxana A. Zhironkina ◽  
Varvara D. Cherepanynets ◽  
Olga S. Strelkova ◽  
Igor I. Kireev ◽  
...  
Keyword(s):  
Dna Replication ◽  
Large Scale ◽  
Chromatin Fibers ◽  
Dynamic Plasticity

Experimental, theoretical, and numerical studies on the response of square plates subjected to blast loading

2011 ◽  
Vol 46 (8) ◽  
pp. 805-816 ◽  
Author(s):  
K H Safari ◽  
J Zamani ◽  
S M R Khalili ◽  
S Jalili
Keyword(s):  
Blast Wave ◽  
Failure Modes ◽  
Scaling Law ◽  
Blast Loading ◽  
Material Failure ◽  
Perfectly Plastic ◽  
Numerical Studies ◽  
Fluid Solid Interaction ◽  
Interaction Problem ◽  
Dynamic Plasticity

This article presents the results of experimental and analytical studies on the response of steel and aluminium square plates with different thicknesses subjected to blast loading. Based on the blast wave details and the scaling law for explosions, a method of determining the blast load is proposed in which ballistic pendulums do not need to be utilized for obtaining the blast wave impulses. The loads applied to the plates are assumed to be the quasi-exponential pressure pulses, which are the same as the explosion overpressures. The theoretical solutions are presented using a rigid, perfectly plastic idealization and are exact within the context of dynamic plasticity. The dynamic energy imparted to structures can cause material failure. The presented investigation considers such a failure for fully clamped plates subjected to a blast loading idealized as an initial velocity distributed uniformly throughout the area. The predicted deflections and general failure modes of the plates are presented and compared with experimental results. Moreover, a numerical simulation is carried out by modelling an FSI (fluid–solid interaction) problem. Results are compared with each other and a better agreement between numerical results with experimental ones is observed.

scholarly journals Dynamic Plasticity of Axons within a Cutaneous Milieu

2010 ◽  
Vol 30 (44) ◽  
pp. 14735-14744 ◽  
Author(s):  
C. Cheng ◽  
G. F. Guo ◽  
J. A. Martinez ◽  
V. Singh ◽  
D. W. Zochodne
Keyword(s):  
Dynamic Plasticity
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