Rac GTPase and the Regulation of NADPH Oxidase in Rice Innate Immunity Response

2009 ◽  
pp. 173-178 ◽  
Author(s):  
Hann Ling Wong ◽  
Tsutomu Kawasaki ◽  
Ko Shimamoto
Keyword(s):  
Innate Immunity ◽  
Nadph Oxidase ◽  
Rac Gtpase ◽  
Immunity Response

PmPPAF is a pro-phenoloxidase activating factor involved in innate immunity response of the shrimp Penaeus monodon

2014 ◽  
Vol 44 (1) ◽  
pp. 163-172 ◽  
Author(s):  
Tracy H.T. Ma ◽  
John A.H. Benzie ◽  
Jian-Guo He ◽  
Cheng-Bo Sun ◽  
Siuming F. Chan
Keyword(s):  
Innate Immunity ◽  
Penaeus Monodon ◽  
Immunity Response

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects

Blood ◽  
2014 ◽  
Vol 124 (4) ◽  
pp. 590-597 ◽  
Author(s):  
Roel P. Gazendam ◽  
John L. van Hamme ◽  
Anton T. J. Tool ◽  
Michel van Houdt ◽  
Paul J. J. H. Verkuijlen ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Candida Albicans ◽  
Nadph Oxidase ◽  
Oxidase Activity ◽  
Human Neutrophils ◽  
Nadph Oxidase Activity ◽  
Key Points

Key Points Human neutrophils use 2 independent mechanisms for the killing of unopsonized and serum-opsonized C albicans. Unopsonized Candida killing depends on CR3 and CARD9 but not dectin-1; opsonized Candida killing on FcγR, PKC, and NADPH oxidase activity.

Participation of Rac GTPase Activating Proteins in the Deactivation of the Phagocytic NADPH Oxidase†

Biochemistry ◽  
2002 ◽  
Vol 41 (34) ◽  
pp. 10710-10716 ◽  
Author(s):  
Patryk Moskwa ◽  
Marie-Claire Dagher ◽  
Marie-Hélène Paclet ◽  
Francoise Morel ◽  
Erzsébet Ligeti
Keyword(s):  
Nadph Oxidase ◽  
Rac Gtpase ◽  
Gtpase Activating Proteins

Current molecular models for NADPH oxidase regulation by Rac GTPase

Blood ◽  
2002 ◽  
Vol 100 (8) ◽  
pp. 2692-2695 ◽  
Author(s):  
Gary M. Bokoch ◽  
Becky A. Diebold
Keyword(s):  
Nadph Oxidase ◽  
Host Defense ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
Oxygen Species ◽  
Molecular Models ◽  
Rac Gtpase ◽  
Rho Family Gtpases ◽  
Rho Family ◽  
Guanosine Triphosphatase ◽  
Reduced Nicotinamide Adenine Dinucleotide

Reactive oxygen species (ROS) have been increasingly recognized as important components of cell signaling in addition to their well-established roles in host defense. The formation of ROS in phagocytic and nonphagocytic cells involves membrane-localized and Rac guanosine triphosphatase (GTPase)–regulated reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase(s). We discuss here the current molecular models for Rac GTPase action in the control of the phagocytic leukocyte NADPH oxidase. As a mechanistically detailed example of Rac GTPase signaling, the NADPH oxidase provides a potential paradigm for signaling by Rho family GTPases in general.

Influence of dietary supplementation with flaxseed and lactobacilli on the cells of local innate immunity response in the jejunal mucosa in piglets after weaning

2015 ◽  
Vol 117 (2) ◽  
pp. 188-195 ◽  
Author(s):  
Stefan Toth ◽  
Zuzana Jonecova ◽  
Peter Kruzliak ◽  
Rachele Ciccocioppo ◽  
Radomira Nemcova
Keyword(s):  
Innate Immunity ◽  
Dietary Supplementation ◽  
Jejunal Mucosa ◽  
Immunity Response
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