Some Aspects of the Developing Brain and Nervous System

Author(s):  
Lawrence D. Longo
Author(s):  
Kohei Shiota

Abstract In this paper, the process of CNS development in human embryos and fetuses is described. The primordium of the nervous system appears as early as during the third week after fertilization, but its differentiation and maturation require a considerably long period of time until after birth. Therefore, the developing brain is vulnerable to various kinds of deleterious environmental effects during the preand perinatal life. This paper aims at giving an overview of the major organogenesis of the brain in human embryos and fetuses.


Vestnik ◽  
2021 ◽  
pp. 112-114
Author(s):  
А.К. Аширбаева ◽  
Л.А. Текебаева ◽  
Е.С. Камидолла ◽  
Д.Ж. Абуов ◽  
М.А. Тян

Статья посвящена оценке безопасности трансмагнитной стимуляции мозга у детей. Хотя количество педиатрических исследований в этой области продолжает расти, действие данного меода на развивающийся мозг остается в значительной степени недостаточно представленным в современной литературе. Из более чем 16000 исследований TMS на людях только 675 (4%) имеют педиатрическую направленность. Изучены наиболее крупные исследования, посвященные безопасности применения ТМС у детей с различными заболеваниями нервной системы. The article is devoted to the assessment of the safety of transmagnetic brain stimulation in children. Although the number of pediatric studies in this area continues to grow, the effect of this method on the developing brain remains largely underrepresented in the current literature. Of the more than 16,000 human TNS studies, only 675 (4%) have a pediatric focus. The largest studies on the safety of the use of TMS in children with various diseases of the nervous system have been studied.


2001 ◽  
Vol 49 (6) ◽  
pp. 735-741 ◽  
Author(s):  
Michael V Johnston ◽  
William H Trescher ◽  
Akira Ishida ◽  
Wako Nakajima ◽  
Alvin Zipursky

1999 ◽  
Vol 11 (4) ◽  
pp. 685-714 ◽  
Author(s):  
LINDA C. MAYES

Within the last decade, many investigators have focused on the physical, neurodevelopmental, and neuropsychological effects of prenatal cocaine exposure on infants and young children. Although inconclusive on many crucial issues, published studies reveal the beginnings of a profile of possible cocaine-related effects on neuropsychological functions subserving arousal and attention regulation. That profile is informed by preclinical studies in which important factors such as duration and type of exposure as well as environmental conditions may be more adequately controlled. In the developing brain, there are a number of candidate mechanisms that account for how prenatal cocaine exposure may interfere with neural ontogeny. This review focuses on the monoamine system, one of the primary sites of action of cocaine in the adult. In the developing organism, monoamines play critical trophic roles through all phases of central nervous system (CNS) ontogeny—cell proliferation, neural migration, growth, maturation, and synaptogenesis. Because of their trophic role in CNS ontogeny, cocaine effects on developing nervous system may be mediated in part through effects on monoamine system ontogeny. In turn, these effects may be expressed behaviorally in disrupted patterns of arousal and attention regulation given that these domains are connected intimately to monoaminergic systems.


Genomics ◽  
2000 ◽  
Vol 66 (1) ◽  
pp. 76-86 ◽  
Author(s):  
Todd A. Gray ◽  
Lidia Hernandez ◽  
Alisoun H. Carey ◽  
Melanie A. Schaldach ◽  
Megan J. Smithwick ◽  
...  

The Lancet ◽  
1977 ◽  
Vol 309 (8008) ◽  
pp. 399-401 ◽  
Author(s):  
P.D. Lewis ◽  
A.J. Patel ◽  
G. Bendek ◽  
R. Balázs

Author(s):  
V. N. Salkov ◽  
R. M. Khudoerkov

Infantile cerebral palsy (cerebral palsy) is one of the most common diseases of the nervoussystem in children. The etiology of cerebral palsy may differ, but structural changes in the brain in children are similar, regardless of clinical form. The paper summarizes the results of the recent studies on structural changes in the brain due to cerebral palsy. The literature sources demonstrate that the term of etiological factors impact on the developing brain of the fetus determines the characteristics of brain damage and localization of the damage, as well as the nature of the response from the nervous system.


1998 ◽  
Vol 106 (1-2) ◽  
pp. 181-204 ◽  
Author(s):  
Burkhard Schütz ◽  
Martin K.-H Schäfer ◽  
Lee E Eiden ◽  
Eberhard Weihe

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