Bacterial Adherence and Host Tropism in Escherichia Coli

1992 ◽  
pp. 133-138
Author(s):  
Staffan Normark ◽  
Britt-Inger Marklund ◽  
Per-Georg Nyholm ◽  
Irmin Pascher ◽  
Nicklas Strömberg
Keyword(s):  
Escherichia Coli ◽  
Bacterial Adherence ◽  
Host Tropism

Absence of Bacterial Adherence in the Establishment of Experimental Mastitis in Mice

1978 ◽  
Vol 15 (6) ◽  
pp. 770-775 ◽  
Author(s):  
J. C. Anderson
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Mammary Gland ◽  
Significant Role ◽  
Streptococcus Agalactiae ◽  
Staphylococcus Epidermidis ◽  
Alveolar Epithelium ◽  
Bacterial Adherence ◽  
E Coli ◽  
Suckling Mice

The possibility of adherence of Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli or Streptococcus agalactiae to the epithelium of the mammary gland was investigated by inoculating them into this gland of mice. S. aureus, S. epidermidis and E. coli did not adhere to alveolar epithelium in suckling or non-suckling mice. S. agalactiae adhered to alveolar epithelium in non-suckling mice but adhesion was not sufficiently strong to withstand suckling. Bacterial adherence probably does not play a significant role in the establishment of mastitis by these organisms.

scholarly journals Role of Lactobacillus in Female Infertility Via Modulating Sperm Agglutination and Immobilization

2021 ◽  
Vol 10 ◽  
Author(s):  
Fenghao Zhang ◽  
Jie Dai ◽  
Tingtao Chen
Keyword(s):  
Escherichia Coli ◽  
Crucial Role ◽  
Vaginal Microbiota ◽  
Female Infertility ◽  
Bacterial Adherence ◽  
Female Fertility ◽  
Physiological Characteristics ◽  
Vaginal Tract

Infertility has become a common problem in recent decades. The pathogenesis of infertility is variable, but microbiological factors account for a large proportion of it. Dysbiosis of vaginal microbiota is reportedly associated with female infertility, but the influence of normal vaginal microbiota on infertility is unclear. In this review, we summarize the physiological characteristics of the vaginal tract and vaginal microbiota communities. We mainly focus on the bacterial adherence of vaginal Lactobacillus species. Given that the adherent effect plays a crucial role in the colonization of bacteria, we hypothesize that the adherent effect of vaginal Lactobacillus may also influence the fertility of the host. We also analyze the agglutination and immobilization effects of other bacteria, especially Escherichia coli, on ejaculated spermatozoa, and speculate on the possible effects of normal vaginal microbiota on female fertility.

Bacterial Adherence in Mastitis Caused by Escherichia coli

1977 ◽  
Vol 14 (6) ◽  
pp. 618-628 ◽  
Author(s):  
J. C. Anderson ◽  
M. R. Burrows ◽  
A. J. Bramley
Keyword(s):  
Escherichia Coli ◽  
Mammary Gland ◽  
Resistant Strain ◽  
Clinical Mastitis ◽  
Bacterial Adherence ◽  
Bovine Mammary Gland ◽  
E Coli ◽  
Mild Disease ◽  
Highly Virulent

The possible role of bacterial adherence in the pathogenesis of experimental mastitis in the mouse was examined with four strains of Escherichia coli. Two of these strains had a known adhesion antigen (K88) and two did not. The K88 antigen did not play a significant role in the virulence or infectivity of E. coli either in the murine or bovine mammary gland. Two E. coli strains, W1 (K88+) and J2 (K88−) were virulent in the mouse but did not adhere to epithelial cells. Both these strains produced clinical mastitis in the cow. A third strain, D282 (K88−), produced mild disease in the mouse but was avirulent in the cow. The fourth strain, 233/1D (K88+), was avirulent in both the mouse and the cow. Strains D282 and 233/1D were killed rapidly by bovine serum whilst J2 and W1 were more resistant. All strains were more sensitive than the control resistant strain E. coli P4, which is known to be highly virulent for the lactating udder.

scholarly journals Bicarbonate Ion Stimulates the Expression of Locus of Enterocyte Effacement-Encoded Genes in Enterohemorrhagic Escherichia coli O157:H7

2002 ◽  
Vol 70 (7) ◽  
pp. 3500-3509 ◽  
Author(s):  
Hiroyuki Abe ◽  
Ichiro Tatsuno ◽  
Toru Tobe ◽  
Akiko Okutani ◽  
Chihiro Sasakawa
Keyword(s):  
Escherichia Coli ◽  
Intestinal Tract ◽  
Optimal Growth ◽  
Growth Conditions ◽  
Luria Bertani ◽  
Enterohemorrhagic Escherichia Coli ◽  
Bacterial Adherence ◽  
Escherichia Coli O157 ◽  
Factors Affecting ◽  
Enterocyte Effacement

ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) strains adhere to the intestinal mucosa and produce an attaching and effacing (A/E) lesion. Most of the genes required to produce A/E lesions are thought to be encoded by the 36-kb pathogenicity island termed the locus for enterocyte effacement (LEE). Although the mechanisms underlying the bacterial adherence, including the genes involved, are still poorly understood, the preferential adherence phenotype of EHEC is thought to depend on the nature of the genes and/or the response of these genes to changes in environmental conditions. To explore the environmental factors affecting EHEC adherence, we used an O157:H7 strain and investigated the optimal growth conditions for its adherence to Caco-2 cells. We observed that EHEC grown in Dulbecco's modified Eagle's medium (DMEM) adhered more efficiently to Caco-2 cells than EHEC grown in Luria-Bertani (LB) broth. Among the components of DMEM, only NaHCO3 was found to remarkably stimulate bacterial adherence. When bacteria were grown in LB broth containing NaHCO3, the production of intimin, Tir, EspA, and EspB was greatly enhanced compared with the production in LB broth. Indeed, the transcription of ler required for LEE-encoded gene expression was promoted in response to the concentration of NaHCO3 in LB broth. Since the concentration of NaHCO3 in the lower intestinal tract has been shown to be relatively high compared with that in the upper small intestine, our results may imply that NaHCO3 is an important signaling factor for promoting colonization of EHEC in the lower intestinal tract in humans.

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