In the manufacturing industry, managers and engineers are trying to sustain their competitiveness by achieving high output and productivity. There are some common problems such as waiting times, failures, reworks in production line that impose extra cost to the companies. Therefore, companies are striving to find methods in order to determine and deal with problems using different methods such as mathematical, statistical and computer simulation. The goal of this paper is to increase the total output production and to improve productivity using computer simulation and Taguchi method. This paper introduces a color manufacturing line as a case study which is simulated using arena 13.9 software. Following that the Taguchi method is applied to assess the effect of controllable and uncontrollable factors on the total output production. According to the result of JMP 10 software to conduct Taguchi experiment, the maximum desirability of productivity will be achieved when the value of factors such service rate of delpak machine=UNIF (30, 40), number of labor=14, inspection time=120 and number of Permil=5. Taguchi Method plays an efficient and suitable role in the process improvement, proposing adjustments that will provide an improvement in the productivity.