Protein Phosphorylation in Endothelial Cell Membranes: Relationship to Growth Control

1989 ◽  
pp. 197-203
Author(s):  
Paul E. DiCorleto ◽  
Andrius Kazlauskas ◽  
Yuko Uratsuji
Keyword(s):  
Endothelial Cell ◽  
Protein Phosphorylation ◽  
Cell Membranes ◽  
Growth Control

scholarly journals Estimates of Michaelis-Menten Constants for the Two Membranes of the Brain Endothelium

1984 ◽  
Vol 4 (2) ◽  
pp. 241-249 ◽  
Author(s):  
Albert Gjedde ◽  
Ove Christensen
Keyword(s):  
Steady State ◽  
Endothelial Cell ◽  
Transport Properties ◽  
Glucose Transport ◽  
Cell Membranes ◽  
Experimental Studies ◽  
Facilitated Diffusion ◽  
Capillary Endothelial Cells ◽  
The Individual ◽  
Tracer Experiments

Tracer studies on facilitated diffusion across the blood–brain barrier lead to the calculation of Michaelis-Menten constants that describe the rate of transport. However, the barrier consists of two endothelial cell membranes, and the relevance of single Michaelis-Menten constants in relation to the two cell membranes is unknown. We have formulated a model of two endothelial cell membranes and show that the measured Michaelis-Menten constants are simple functions of the properties of the individual membranes when transport across the endothelium is rapid ( P1 > 10−6 cm s−1). We also show that the Michaelis-Menten constants determined in tracer experiments describe facilitated diffusion in the steady state only if the two membranes have similar transport properties. As an application of this observation, we have examined three experimental studies that measure glucose transport in the steady state and show that the Michaelis-Menten constants for glucose transport calculated from the tracer experiments are equal to the constants calculated from the steady-state experiments. We conclude that the luminal and abluminal membranes of brain capillary endothelial cells have equal glucose transport properties.

Effects of Zn2+ ions on protein phosphorylation in epithelial cell membranes

1983 ◽  
Vol 115 (3) ◽  
pp. 305-312 ◽  
Author(s):  
Kari Alitalo ◽  
Jorma Keski-Oja ◽  
Paul Bornstein
Keyword(s):  
Epithelial Cell ◽  
Protein Phosphorylation ◽  
Cell Membranes

Activation of the plasma kallikrein/kinin system on endothelial cell membranes

1999 ◽  
Vol 43 (2-3) ◽  
pp. 109-114 ◽  
Author(s):  
Rasmus Røjkjær ◽  
Alvin H Schmaier
Keyword(s):  
Endothelial Cell ◽  
Cell Membranes ◽  
Plasma Kallikrein ◽  
Kinin System ◽  
Kallikrein Kinin System

Specific binding of leukotriene C4 to endothelial cell membranes

1987 ◽  
Vol 26 (3) ◽  
pp. 233-240 ◽  
Author(s):  
Agnès Muller ◽  
Chantal Ghiglieri-Bertez ◽  
Guy Modat ◽  
Claude Bonne
Keyword(s):  
Endothelial Cell ◽  
Cell Membranes ◽  
Specific Binding ◽  
Leukotriene C4
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