Visna Virus Genome

1990 ◽  
pp. 75-98 ◽  
Author(s):  
Matthew A. Gonda
Keyword(s):  
Virus Genome ◽  
Visna Virus

In situ PCR-associated immunohistochemistry identifies cell types harbouring the Maedi-Visna virus genome in tissue sections of sheep infected naturally

2003 ◽  
Vol 107 (2) ◽  
pp. 121-127 ◽  
Author(s):  
Maria Luisa Carrozza ◽  
Maurizio Mazzei ◽  
Patrizia Bandecchi ◽  
Mario Arispici ◽  
Francesco Tolari
Keyword(s):  
Cell Types ◽  
Virus Genome ◽  
In Situ Pcr ◽  
Tissue Sections ◽  
Visna Virus ◽  
Maedi Visna Virus

scholarly journals Visna Virus dUTPase Is Dispensable for Neuropathogenicity

1998 ◽  
Vol 72 (2) ◽  
pp. 1657-1661 ◽  
Author(s):  
Gudmundur Pétursson ◽  
Priscilla Turelli ◽  
Sigrídur Matthíasdóttir ◽  
Gudmundur Georgsson ◽  
Ólafur S. Andrésson ◽  
...  
Keyword(s):  
Viral Load ◽  
Major Part ◽  
Virus Genome ◽  
Mutant Virus ◽  
Intracerebral Injection ◽  
Wild Type ◽  
Visna Virus ◽  
The Brain

ABSTRACT The major part of the dUTPase-encoding region of the visna virus genome was deleted. Intracerebral injection of the mutant virus resulted in a somewhat reduced viral load compared to that resulting from injection of the wild type, especially in the lungs, but the neuropathogenic effects were comparable. The dUTPase gene is dispensable for induction of lesions in the brain.

The open reading frame S of visna virus genome is a trans-activating gene

Virology ◽  
1989 ◽  
Vol 171 (1) ◽  
pp. 170-178 ◽  
Author(s):  
I. Gourdou ◽  
V. Mazarin ◽  
G. Quérat ◽  
N. Sauze ◽  
R. Vigne
Keyword(s):  
Virus Genome ◽  
Open Reading Frame ◽  
Reading Frame ◽  
Visna Virus

A Multivariate Data Analytics Approach Revealed No Footprint of APOBEC3 Proteins in Hepatitis B Virus Genome

2020 ◽  
Author(s):  
Hamid Alinejad-Rokny ◽  
Eisa Zarepour ◽  
Hoda Khadijeh Jahanian ◽  
Amin Beheshti ◽  
Abdollah Dehzangi
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Data Analytics ◽  
Multivariate Data ◽  
Virus Genome ◽  
B Virus ◽  
Apobec3 Proteins

Molecular characterization of SARS-CoV-2

2020 ◽  
Vol 20 ◽  
Author(s):  
Miribane Dërmaku-Sopjani ◽  
Mentor Sopjani
Keyword(s):  
Public Health ◽  
Drug Targets ◽  
Virus Genome ◽  
Health Crisis ◽  
Public Health Crisis ◽  
Therapeutic Drugs ◽  
New Public Health ◽  
New Public ◽  
And Function

Abstract:: The coronavirus disease 2019 (COVID-19) is currently a new public health crisis threatening the world. This pandemic disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus has been reported to be originated in bats and by yet unknown intermediary animals were transmitted to humans in China 2019. The SARSCoV- 2 spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome coronavirus (MERSCoV) but has reduced fatality. At present, the SARS-CoV-2 has caused about a 1.16 million of deaths with more than 43.4 million confirmed cases worldwide, resulting in a serious threat to public health globally with yet uncertain impact. The disease is transmitted by inhalation or direct contact with an infected person. The incubation period ranges from 1 to 14 days. COVID-19 is accompanied by various symptoms, including cough, fatigue. In most people the disease is mild, but in some other people, such as in elderly and people with chronic diseases, it may progress from pneumonia to a multi-organ dysfunction. Many people are reported asymptomatic. The virus genome is sequenced, but new variants are reported. Numerous biochemical aspects of its structure and function are revealed. To date, no clinically approved vaccines and/or specific therapeutic drugs are available to prevent or treat the COVID-19. However, there are reported intensive researches on the SARSCoV- 2 to potentially identify vaccines and/or drug targets, which may help to overcome the disease. In this review, we discuss recent advances in understanding the molecular structure of SARS-CoV-2 and its biochemical characteristics.

First Detection of Tobacco Mosaic Virus in Tobacco Fields in Northern Lebanon

2020 ◽  
Vol 20 ◽  
Author(s):  
Rami Obeid ◽  
Elias Wehbe ◽  
Mohamad Rima ◽  
Mohammad Kabara ◽  
Romeo Al Bersaoui ◽  
...  
Keyword(s):  
Tobacco Mosaic Virus ◽  
Mosaic Virus ◽  
Viral Genome ◽  
Virus Genome ◽  
Enzyme Linked Immunosorbent Assay ◽  
Virus Family ◽  
Crop Fields ◽  
Wide Range ◽  
Almost All ◽  
Das Elisa

Background: Tobacco mosaic virus (TMV) is the most known virus in the plant mosaic virus family and is able to infect a wide range of crops, in particularly tobacco, causing a production loss. Objectives: Herein, and for the first time in Lebanon, we investigated the presence of TMV infection in crops by analyzing 88 samples of tobacco, tomato, cucumber and pepper collected from different regions in North Lebanon. Methods: Double-antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA), revealed a potential TMV infection of four tobacco samples out of 88 crops samples collected. However, no tomato, cucumber and pepper samples were infected. The TMV+ tobacco samples were then extensively analyzed by RT-PCR to detect viral RNA using different primers covering all the viral genome. Results and Discussion: PCR results confirmed those of DAS-ELISA showing TMV infection of four tobacco samples collected from three crop fields of North Lebanon. In only one of four TMV+ samples, we were able to amplify almost all the regions of viral genome, suggesting possible mutations in the virus genome or an infection with a new, not yet identified, TMV strain. Conclusion: Our study is the first in Lebanon revealing TMV infection in crop fields, and highlighting the danger that may affect the future of agriculture.

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